Pharmacogenetics and pharmacogenomics. (Q34285350)

1 August 2017

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title

Pharmacogenetics and pharmacogenomics. (English)

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1 August 2017

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J S Leeder

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1 August 2017

publication date

1 June 2001

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Pediatric Clinics of North America

1 August 2017

published in

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

765-781

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Maturation of caffeine elimination in infancy

1 August 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Population distribution and effects on drug metabolism of a genetic variant in the 5' promoter region of CYP3A4

7 January 2021

1 reference

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Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Allelic and functional variability of cytochrome P4502C9.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Phenytoin elimination in newborns

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Genetic and environmental factors associated with variation of human xenobiotic glucuronidation and sulfation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Population pharmacokinetics of midazolam in neonates.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Biotransformation of caffeine in human liver microsomes from foetuses, neonates, infants and adults

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Michaelis-Menten pharmacokinetics of diphenylhydantoin and application in the pediatric age patient

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Nomenclature for human CYP2D6 alleles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Glucuronidation in humans. Pharmacogenetic and developmental aspects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Pharmacogenomics: translating functional genomics into rational therapeutics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Association of CYP3A4 genotype with treatment-related leukemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

CYP2C19 genotype status and effect of omeprazole on intragastric pH in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Biochemistry and molecular biology of the human CYP2C subfamily

7 January 2021

1 reference

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Allelic variants of human cytochrome P450 2C9: baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Expression of xenobiotic-metabolizing cytochrome P450 forms in human adult and fetal liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

The use of caffeine for enzyme assays: a critical appraisal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Pharmacokinetic studies in paediatric patients. Clinical and ethical considerations

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation

7 January 2021

1 reference

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Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

CYP3A gene expression in human gut epithelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

The metabolization of carbamazepine to CBZ-10,11-epoxide in children from the newborn age to adolescence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Alterations in theophylline metabolism during the first year of life

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

INSUFFICIENT PARAPHYDROXYLATION AS A CAUSE OF DIPHENYLHYDANTOIN TOXICITY

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Expression of CYP3A in the Human Liver — Evidence that the Shift between CYP3A7 and CYP3A4 Occurs Immediately After Birth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Congenital thiopurine methyltransferase deficiency and 6-mercaptopurine toxicity during treatment for acute lymphoblastic leukaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Thiopurine methyltransferase deficiency in childhood lymphoblastic leukaemia: 6-mercaptopurine dosage strategies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Pharmacokinetic observations of phenytoin disposition in the newborn and young infant

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

The effects of genetic polymorphisms of CYP2C9 and CYP2C19 on phenytoin metabolism in Japanese adult patients with epilepsy: studies in stereoselective hydroxylation and population pharmacokinetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Phenotype and genotype analysis of debrisoquine hydroxylase (CYP2D6) in a black Zimbabwean population. Reduced enzyme activity and evaluation of metabolic correlation of CYP2D6 probe drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

A novel mutant variant of the CYP2D6 gene (CYP2D6*17) common in a black African population: association with diminished debrisoquine hydroxylase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Evaluation of a scheme for establishing and maintaining dosage of theophylline in ambulatory patients with chronic asthma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Acetaminophen elimination kinetics in neonates, children, and adults

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Genetic polymorphism in the 5'-flanking region of human CYP1A2 gene: effect on the CYP1A2 inducibility in humans

7 January 2021

1 reference

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Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms*

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Morphine glucuronidation in human fetal and adult liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

First-pass metabolism of midazolam by the human intestine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

The pharmacokinetics of midazolam in paediatric patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

The hypoalgesic effect of tramadol in relation to CYP2D6*

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Carbamazepine and its 10,11-epoxide in children and adults with epilepsy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Free concentration of carbamazepine and carbamazepine-10,11-epoxide in children and adults. Influence of age and phenobarbitone co-medication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: evidence for an allelic variant with altered catalytic activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Morphine pharmacokinetics and pain assessment in premature newborns

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

The pharmacogenetics of codeine hypoalgesia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Genetic association between sensitivity to warfarin and expression of CYP2C9*3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Expression of CYP2D6 in developing human liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Noninvasive tests of CYP3A enzymes

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Chloramphenicol in the newborn infant. A physiologic explanation of its toxicity when given in excessive doses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

The human hepatic cytochromes P450 involved in drug metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Isolation and characterization of human fetal liver cytochrome P450HLp2: a third member of the P450III gene family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Thiopurine methyltransferase polymorphic tandem repeat: genotype-phenotype correlation analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Expression of functional cytochrome P4501A1 in human embryonic hepatic tissues during organogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Characterization of human cytochromes P450 involved in theophylline 8-hydroxylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

inferred from DOI database lookup

7 January 2021

based on heuristic

Role of cytochrome P4501A2 in chemical carcinogenesis: implications for human variability in expression and enzyme activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

inferred from DOI database lookup

7 January 2021

based on heuristic

The effect of age, gender, and sexual maturation on the caffeine breath test

1 reference

https://api.crossref.org/works/10.1016%2FS0031-3955%2805%2970338-2

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0031-3955(05)70338-2

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1 August 2017

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