Oral delivery of taxanes (Q34273659)

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Language	Label	Description	Also known as
English	Oral delivery of taxanes	scientific article

Statements

instance of

scholarly article

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Europe PubMed Central

PubMed publication ID

11392449

retrieved

1 August 2017

review article

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Europe PubMed Central

title

Oral delivery of taxanes (English)

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Europe PubMed Central

PubMed publication ID

11392449

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1 August 2017

author

Jos Beijnen

series ordinal

2

object named as

J H Beijnen

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Europe PubMed Central

PubMed publication ID

11392449

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1 August 2017

author name string

M M Malingré

series ordinal

1

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Europe PubMed Central

PubMed publication ID

11392449

retrieved

1 August 2017

J H Schellens

series ordinal

3

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Europe PubMed Central

PubMed publication ID

11392449

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1 August 2017

publication date

1 May 2001

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stated in

Europe PubMed Central

PubMed publication ID

11392449

retrieved

1 August 2017

published in

Investigational New Drugs

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stated in

Europe PubMed Central

PubMed publication ID

11392449

retrieved

1 August 2017

volume

19

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stated in

Europe PubMed Central

PubMed publication ID

11392449

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1 August 2017

issue

2

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Europe PubMed Central

PubMed publication ID

11392449

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1 August 2017

page(s)

155-162

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Europe PubMed Central

PubMed publication ID

11392449

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1 August 2017

cites work

Coadministration of oral cyclosporin A enables oral therapy with paclitaxel

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

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Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

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Hypersensitivity reactions from taxol

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I and pharmacokinetic study of oral paclitaxel

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

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Patient preferences for oral versus intravenous palliative chemotherapy

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of non-small-cell lung cancer with prolonged oral etoposide

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

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Phase I trial of docetaxel administered by weekly infusion in patients with advanced refractory cancer

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

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Oral chemotherapy: rationale and future directions

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and excretion of paclitaxel after oral administration in combination with cyclosporin A and after i.v. administration

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

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Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemistry of multidrug resistance mediated by the multidrug transporter

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Functional Role of P-Glycoprotein in the Blood–Brain Barrier

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma pharmacokinetics and tissue distribution of paclitaxel in CD2F1 mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase I and pharmacokinetic study of bi-daily dosing of oral paclitaxel in combination with cyclosporin A.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human (MDR1) and mouse (mdr1, mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced oral absorption and decreased elimination of paclitaxel in mice cotreated with cyclosporin A

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taxanes: a new class of antitumor agents.

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

What have we learnt thus far from mice with disrupted P-glycoprotein genes?

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-administration of cyclosporin enables oral therapy with paclitaxel

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human cytochrome P450 3A4: enzymatic properties of a purified recombinant fusion protein containing NADPH-P450 reductase

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cremophor EL causes (pseudo-) non-linear pharmacokinetics of paclitaxel in patients

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue distribution, metabolism and excretion of paclitaxel in mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokinetic/pharmacodynamic relationships in humans

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacological role of P-glycoprotein in the intestinal epithelium

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paclitaxel (taxol)

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

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A phase I and pharmacology study of an oral platinum complex, JM216: dose-dependent pharmacokinetics with single-dose administration

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

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Pharmacokinetics of paclitaxel and carboplatin in a dose-escalating and dose-sequencing study in patients with non-small-cell lung cancer. The European Cancer Centre

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of a multidrug-resistance gene in human tumors and tissues

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

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[Pharmacokinetics of paclitaxel in experimental animals. Part 1. Blood level]

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biochemistry of P-glycoprotein-mediated multidrug resistance

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacology of anticancer agents in relation to formulations and administration routes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The oral route for the administration of cytotoxic drugs: strategies to increase the efficiency and consistency of drug delivery

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of taxol by human hepatic microsomes and liver slices: participation of cytochrome P450 3A4 and an unknown P450 enzyme

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonlinear pharmacokinetics of paclitaxel in mice results from the pharmaceutical vehicle Cremophor EL

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cremophor EL-mediated alteration of paclitaxel distribution in human blood: clinical pharmacokinetic implications.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology and toxicology of Cremophor EL diluent

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioavailability of low-dose oral etoposide

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11392449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1023/A:1010635000879

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11392449

retrieved

1 August 2017

Dimensions Publication ID

1037266095

0 references

PubMed publication ID

11392449

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11392449

retrieved

1 August 2017

 

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