Tumor suppression by a severely truncated species of retinoblastoma protein (Q34278098)

1 August 2017

title

Tumor suppression by a severely truncated species of retinoblastoma protein (English)

1 reference

ORCID Public Data File 2021

1 August 2017

1 reference

Bart O Williams

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author name string

Hong Yang

1 reference

1 August 2017

Phillip W Hinds

1 reference

1 August 2017

T Shane Shih

1 reference

1 August 2017

Tyler Jacks

1 reference

1 August 2017

Roderick T Bronson

1 reference

1 August 2017

David M Livingston

1 reference

1 August 2017

language of work or name

English

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publication date

1 May 2002

1 reference

Molecular and Cellular Biology

1 August 2017

published in

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

3103-3110

1 reference

Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system

1 August 2017

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1 reference

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6 July 2018

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6 July 2018

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Retinoblastoma protein meets chromatin

6 July 2018

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6 July 2018

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Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes

6 July 2018

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Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progression

6 July 2018

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6 July 2018

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p107 is a suppressor of retinoblastoma development in pRb-deficient mice

6 July 2018

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Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7.

6 July 2018

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Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7

6 July 2018

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Rb interacts with histone deacetylase to repress transcription

6 July 2018

1 reference

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Retinoblastoma protein represses transcription by recruiting a histone deacetylase

6 July 2018

1 reference

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Retinoblastoma protein recruits histone deacetylase to repress transcription

6 July 2018

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Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

6 July 2018

1 reference

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Mutations of N-terminal regions render the retinoblastoma protein insufficient for functions in development and tumor suppression.

6 July 2018

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RB and hbrm cooperate to repress the activation functions of E2F1

6 July 2018

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A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins

6 July 2018

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Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins

6 July 2018

1 reference

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The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway

6 July 2018

1 reference

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A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

6 July 2018

1 reference

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Overproduction of Rb protein after the G1/S boundary causes G2 arrest

6 July 2018

1 reference

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Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation

6 July 2018

1 reference

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Expression of a retinoblastoma transgene results in dwarf mice

6 July 2018

1 reference

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Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

A bipartite nuclear localization signal in the retinoblastoma gene product and its importance for biological activity

6 July 2018

1 reference

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A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

6 July 2018

1 reference

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Molecular etiology of low-penetrance retinoblastoma in two pedigrees.

6 July 2018

1 reference

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p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

6 July 2018

1 reference

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Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice

6 July 2018

1 reference

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Enhanced tumor cell growth suppression by an N-terminal truncated retinoblastoma protein

6 July 2018

1 reference

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Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice

6 July 2018

1 reference

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Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences

6 July 2018

1 reference

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The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

6 July 2018

1 reference

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The retinoblastoma tumor suppressor protein.

6 July 2018

1 reference

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Interaction between the retinoblastoma protein and the oncoprotein MDM2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

The retinoblastoma protein and cell cycle control

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

Detection of a novel cell cycle-regulated kinase activity that associates with the amino terminus of the retinoblastoma protein in G2/M phases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

Stimulation of Human Insulin Receptor Gene Expression by Retinoblastoma Gene Product

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

Mechanism of active transcriptional repression by the retinoblastoma protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

Structure and expression of the murine retinoblastoma gene and characterization of its encoded protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

Identification of a growth suppression domain within the retinoblastoma gene product

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

Effects of an Rb mutation in the mouse

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

DNA replication control through interaction of E2F-RB and the origin recognition complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

Enhanced tumor suppressor gene therapy via replication-deficient adenovirus vectors expressing an N-terminal truncated retinoblastoma protein

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

Retinoblastoma gene mutations in primary human prostate cancer.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133747

RB regulates the stability and the apoptotic function of p53 via MDM2

28 October 2018

1 reference

12 December 2020

Structural alterations at the putative retinoblastoma locus in some human leukemias and preleukemia

1 reference

12 December 2020

The large subunit of replication factor C promotes cell survival after DNA damage in an LxCxE motif- and Rb-dependent manner

1 reference

12 December 2020

Heterozygous Rb-1 delta 20/+mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance

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12 December 2020

The retinoblastoma gene is involved in malignant progression of astrocytomas

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12 December 2020

10.1128/MCB.22.9.3103-3110.2002

Identifiers

DOI

1 reference

release_4qzwud3gsrhvdaqx42qh5tyfyi

1 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/4qzwud3gsrhvdaqx42qh5tyfyi

24 November 2022

mapped directly with Wikidata item

PMC publication ID

133747

1 reference

1 August 2017

1 reference