Furan in heat-treated foods: formation, exposure, toxicity, and aspects of risk assessment (Q34277773)

1 August 2017

title

Furan in heat-treated foods: formation, exposure, toxicity, and aspects of risk assessment (English)

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1 August 2017

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ChEBI release 2020-05-28

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Sabrina Moro

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1 August 2017

James Kevin Chipman

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1 August 2017

Jan-Willem Wegener

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1 August 2017

Carolin Hamberger

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1 August 2017

Wolfgang Dekant

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1 August 2017

Angela Mally

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1 August 2017

publication date

29 May 2012

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Molecular Nutrition and Food Research

1 August 2017

published in

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

1197-1211

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Origin and mechanistic pathways of formation of the parent furan--a food toxicant

1 August 2017

cites work

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https://api.crossref.org/works/10.1002%2FMNFR.201200093

Factors affecting thermally induced furan formation.

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201200093

Some factors affecting the formation of furan in heated foods

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201200093

Update of results on the monitoring of furan levels in food

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201200093

Furan levels in fruit and vegetables juices, nutrition drinks and bakery products

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201200093

Identification of cis-2-butene-1,4-dial as a microsomal metabolite of furan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Furan-induced liver cell proliferation and apoptosis in female B6C3F1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Degraded protein adducts of cis-2-butene-1,4-dial are urinary and hepatocyte metabolites of furan

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Identification of a cis-2-butene-1,4-dial-derived glutathione conjugate in the urine of furan-treated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Biomarkers of furan exposure by metabolic profiling of rat urine with liquid chromatography-tandem mass spectrometry and principal component analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Hepatobiliary toxicity of furan: identification of furan metabolites in bile of male f344/n rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Identification of furan metabolites derived from cysteine-cis-2-butene-1,4-dial-lysine cross-links

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Glutathione trapping to measure microsomal oxidation of furan to cis-2-butene-1,4-dial

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Increased furan tolerance in Escherichia coli due to a cryptic ucpA gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Evaluation of genotoxicity, pathological lesions, and cell proliferation in livers of rats and mice treated with furan

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201200093

Integration of clinical and gene expression endpoints to explore furan-mediated hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Subchronic oral toxicity study of furan in Fischer-344 rats

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201200093

Induction and progression of cholangiofibrosis in rat liver injured by oral administration of furan

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Subchronic oral toxicity study of furan in B6C3F1 Mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Furan-induced dose-response relationships for liver cytotoxicity, cell proliferation, and tumorigenicity (furan-induced liver tumorigenicity).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Toxic and genotoxic effects of oral administration of furan in mouse liver.

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201200093

Assessment of in vivo genotoxicity of the rodent carcinogen furan: evaluation of DNA damage and induction of micronuclei in mouse splenocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

A reactive metabolite of furan, cis-2-butene-1,4-dial, is mutagenic in the Ames assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

DNA-damaging activity of biotic and xenobiotic aldehydes in Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Characterization of nucleoside adducts of cis-2-butene-1,4-dial, a reactive metabolite of furan

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Low doses of the carcinogen furan alter cell cycle and apoptosis gene expression in rat liver independent of DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Evidence of oxidative stress and associated DNA damage, increased proliferative drive, and altered gene expression in rat liver produced by the cholangiocarcinogenic agent furan

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Gene expression and epigenetic changes by furan in rat liver

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201200093

Functional and proliferative effects of repeated low-dose oral administration of furan in rat liver

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201200093

Gene expression profiling reveals multiple toxicity endpoints induced by hepatotoxicants

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201200093

Identification and pathway mapping of furan target proteins reveal mitochondrial energy production and redox regulation as critical targets of furan toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

Application of the margin of exposure (MoE) approach to substances in food that are genotoxic and carcinogenic: example: furan (CAS No. 110-00-9).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201200093

21 January 2018

Identifiers

DOI

10.1002/MNFR.201200093

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release_e27qkorzbzcwbjo752chg6ezqe

1 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/e27qkorzbzcwbjo752chg6ezqe

mapped directly with Wikidata item

24 November 2022

based on heuristic

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