Evolutionary pathways in BRCA1-associated breast tumors (Q34277174)

1 August 2017

title

Evolutionary pathways in BRCA1-associated breast tumors (English)

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1 August 2017

Mithat Gönen

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1 August 2017

Joanne L Blum

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1 August 2017

Judy E Garber

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1 August 2017

Kornelia Polyak

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1 August 2017

Franziska Michor

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1 August 2017

Filipe C Martins

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1 August 2017

Subhajyoti De

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1 August 2017

Vanessa Almendro

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1 August 2017

So Yeon Park

1 reference

1 August 2017

William Herlihy

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1 August 2017

Gabrielle Ethington

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1 August 2017

Stuart J Schnitt

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1 August 2017

Nadine Tung

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1 August 2017

Katharina Fetten

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1 August 2017

publication date

10 April 2012

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1 August 2017

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

503-511

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Computational modeling of pancreatic cancer reveals kinetics of metastasis suggesting optimum treatment strategies

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Temporal dissection of tumorigenesis in primary cancers

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Evolutionary dynamics of BRCA1 alterations in breast tumorigenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Prevalence and predictors of loss of wild type BRCA1 in estrogen receptor positive and negative BRCA1-associated breast cancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

A mathematical framework to determine the temporal sequence of somatic genetic events in cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Breast Cancer Predisposition Syndromes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

The molecular pathogenesis of hereditary ovarian carcinoma: alterations in the tubal epithelium of women with BRCA1 and BRCA2 mutations.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

PIK3CA mutations in in situ and invasive breast carcinomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Breast cancer risk associated with BRCA1 and BRCA2 in diverse populations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Heterogenic loss of the wild-type BRCA allele in human breast tumorigenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Identification of domains of BRCA1 critical for the ubiquitin-dependent inhibition of centrosome function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Centrosomal microtubule nucleation activity is inhibited by BRCA1-dependent ubiquitination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Cancer genes and the pathways they control

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

BRCA2 is inactivated late in the development of pancreatic intraepithelial neoplasia: evidence and implications

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

BRCA1 is associated with the centrosome during mitosis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Association of BRCA1 with Rad51 in mitotic and meiotic cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Mutation and cancer: statistical study of retinoblastoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

High incidence of protein-truncating TP53 mutations in BRCA1-related breast cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Evidence of haplotype insufficiency in human cells containing a germline mutation in BRCA1 or BRCA2.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738298

Gamma-rays-induced death of human cells carrying mutations of BRCA1 or BRCA2

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22628410

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tumorigenesis as a consequence of genetic instability in Brca1 mutant mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22628410

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The polyglutamylated lateral chain of alpha-tubulin plays a key role in flagellar motility

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22628410

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/2159-8290.CD-11-0325

1 reference

1 August 2017

1 reference

1 August 2017

1 reference