The contribution of endogenous sources of DNA damage to the multiple mutations in cancer (Q34263814)

1 August 2017

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title

The contribution of endogenous sources of DNA damage to the multiple mutations in cancer (English)

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ORCID Public Data File 2021

1 August 2017

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author name string

Jackson AL

series ordinal

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1 August 2017

Loeb LA

series ordinal

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1 August 2017

language of work or name

English

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publication date

1 June 2001

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1 August 2017

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1 August 2017

volume

477

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1 August 2017

issue

1-2

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1 August 2017

page(s)

7-21

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Genetic instability of cancer cells is proportional to their degree of aneuploidy

1 August 2017

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Karyotypic evolution in human malignant melanoma

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Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer

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A genetic model for colorectal tumorigenesis

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7 January 2021

When checkpoints fail

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Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbrück fluctuation analysis

7 January 2021

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Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

7 January 2021

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DNA copy number changes in development and progression in leiomyosarcomas of soft tissues

7 January 2021

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Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cells

7 January 2021

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On the origin of multiple mutations in human cancers

7 January 2021

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Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

7 January 2021

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Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

7 January 2021

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The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

7 January 2021

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Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

7 January 2021

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Mutation of a mutL homolog in hereditary colon cancer

7 January 2021

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APC mutations in colorectal tumors with mismatch repair deficiency

7 January 2021

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Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

7 January 2021

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Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours

7 January 2021

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Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

7 January 2021

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Diploid predominance in hereditary nonpolyposis colorectal carcinoma evaluated by flow cytometry

7 January 2021

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Hereditary nonpoiyposis colorectal cancer (lynch syndrome II): Diploid malignancies with prolonged survival

7 January 2021

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Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation

7 January 2021

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Rate of depurination of native deoxyribonucleic acid

7 January 2021

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Metal-induced lethality and mutagenesis: possible role of apurinic intermediates

7 January 2021

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Mutagenesis by apurinic/apyrimidinic sites

7 January 2021

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Heat-induced deamination of cytosine residues in deoxyribonucleic acid

7 January 2021

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Mutagenic deamination of cytosine residues in DNA

7 January 2021

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The spectrum of spontaneous mutations in a Saccharomyces cerevisiae uracil-DNA-glycosylase mutant limits the function of this enzyme to cytosine deamination repair

7 January 2021

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5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes

7 January 2021

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A genetic system to identify DNA polymerase beta mutator mutants

7 January 2021

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DNA-replication fidelity, mismatch repair and genome instability in cancer cells

7 January 2021

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DNA polymerases alpha, delta, and epsilon: three distinct enzymes from HeLa cells

7 January 2021

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Production of active mouse DNA polymerase β in bacteria

7 January 2021

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Mismatch repair in replication fidelity, genetic recombination, and cancer biology

7 January 2021

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Specific binding of human MSH2.MSH6 mismatch-repair protein heterodimers to DNA incorporating thymine- or uracil-containing UV light photoproducts opposite mismatched bases.

7 January 2021

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Purine deoxynucleoside metabolism in human melanoma cells with a high spontaneous mutation rate

7 January 2021

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The fragile X syndrome d(CGG)n nucleotide repeats form a stable tetrahelical structure

7 January 2021

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Proliferating cell nuclear antigen promotes misincorporation catalyzed by calf thymus DNA polymerase delta

7 January 2021

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Requirement of mammalian DNA polymerase-beta in base-excision repair.

7 January 2021

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DNA polymerase beta expression differences in selected human tumors and cell lines

7 January 2021

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Dominant negative rat DNA polymerase beta mutants interfere with base excision repair in Saccharomyces cerevisiae

7 January 2021

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Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs

7 January 2021

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Overexpression of DNA polymerase β: a genomic instability enhancer process

7 January 2021

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7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

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UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V.

7 January 2021

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Thymine-thymine dimer bypass by yeast DNA polymerase zeta

7 January 2021

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hRAD30 mutations in the variant form of xeroderma pigmentosum

7 January 2021

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Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta

7 January 2021

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Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis

7 January 2021

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Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity

7 January 2021

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The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

7 January 2021

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The human DINB1 gene encodes the DNA polymerase Poltheta

7 January 2021

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Novel DNA polymerases offer clues to the molecular basis of mutagenesis

7 January 2021

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7 January 2021

Oxidative Decay of DNA

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Prooxidant states and tumor promotion

7 January 2021

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Skin tumor-promoting activity of benzoyl peroxide, a widely used free radical-generating compound

7 January 2021

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Phagocytes as carcinogens: malignant transformation produced by human neutrophils.

7 January 2021

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Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases

7 January 2021

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Antioxidants and multistage carcinogenesis in mouse skin

7 January 2021

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Tumorigenic conversion of a non-tumorigenic rat urothelial cell line by overexpression of H2O2-generating peroxisomal fatty acyl-CoA oxidase

7 January 2021

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Cell transformation by the superoxide-generating oxidase Mox1

7 January 2021

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Radiation-induced decomposition of the purine bases within DNA and related model compounds

7 January 2021

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Apurinic sites as mutagenic intermediates

7 January 2021

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Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro.

7 January 2021

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Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA.

7 January 2021

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Base substitutions, frameshifts, and small deletions constitute ionizing radiation-induced point mutations in mammalian cells

7 January 2021

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Synthesis of oligonucleotides containing two putatively mutagenic DNA lesions: 5-hydroxy-2'-deoxyuridine and 5-hydroxy-2'-deoxycytidine

7 January 2021

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Oxidized, deaminated cytosines are a source of C --> T transitions in vivo

7 January 2021

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Mutations induced by methylene blue plus light in single-stranded M13mp2

7 January 2021

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Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome.

7 January 2021

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Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

7 January 2021

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Tandem double CC-->TT mutations are produced by reactive oxygen species

7 January 2021

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Detection of tandem CC-->TT mutations induced by oxygen radicals using mutation-specific PCR

7 January 2021

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Oxygen radical induced mutagenesis is DNA polymerase specific.

7 January 2021

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Induction of microsatellite instability by oxidative DNA damage

7 January 2021

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Microsatellite instability induced by hydrogen peroxide in Escherichia coli

7 January 2021

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Oxidants, antioxidants, and the degenerative diseases of aging

7 January 2021

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Gastric antioxidant, nitrites, and mucosal lipoperoxidation in chronic gastritis and Helicobacter pylori infection

7 January 2021

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Oxidative DNA damage accumulation in gastric carcinogenesis

7 January 2021

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Risk and natural history of colonic neoplasia in patients with primary sclerosing cholangitis and ulcerative colitis

7 January 2021

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Genomic instability is an early event during the progression pathway of ulcerative-colitis-related neoplasia

7 January 2021

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Urinary aflatoxin biomarkers and risk of hepatocellular carcinoma

7 January 2021

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Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma

7 January 2021

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Association between reactive oxygen species and disease activity in chronic hepatitis C

7 January 2021

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Iron storage, lipid peroxidation and glutathione turnover in chronic anti-HCV positive hepatitis

7 January 2021

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Vitamin E reduces chromosomal damage and inhibits hepatic tumor formation in a transgenic mouse model

7 January 2021

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10.1016/S0027-5107(01)00091-4

7 January 2021

Identifiers

DOI

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1 August 2017

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