Rapid expansion of CD8+ T cells in wild-type and type I interferon receptor-deficient mice correlates with protection after low-dose emergency immunization with modified vaccinia virus Ankara (Q34262138)

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English	Rapid expansion of CD8+ T cells in wild-type and type I interferon receptor-deficient mice correlates with protection after low-dose emergency immunization with modified vaccinia virus Ankara	scientific article

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1 August 2017

Rapid expansion of CD8+ T cells in wild-type and type I interferon receptor-deficient mice correlates with protection after low-dose emergency immunization with modified vaccinia virus Ankara (English)

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1 August 2017

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vaccinia virus

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Martin C Langenmayer

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11 June 2020

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11 June 2020

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11 June 2020

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Asisa Volz

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Sylvia Jany

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9 July 2014

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1 August 2017

Journal of Virology

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11 June 2020

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11 June 2020

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11 June 2020

10946-10957

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11 June 2020

The effects of post-exposure smallpox vaccination on clinical disease presentation: addressing the data gaps between historical epidemiology and modern surrogate model data

1 reference

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Clinical findings in 111 cases of influenza A (H7N9) virus infection

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6 July 2018

Memory CD8⁺ T cells can outsource IFN-γ production but not cytolytic killing for antiviral protection.

1 reference

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6 July 2018

Immunodomination during peripheral vaccinia virus infection.

1 reference

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6 July 2018

Clinical development of Modified Vaccinia virus Ankara vaccines

1 reference

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Protective efficacy of Modified Vaccinia virus Ankara in preclinical studies

1 reference

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Kinetics of antigen expression and epitope presentation during virus infection.

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Signal 3 cytokines as modulators of primary immune responses during infections: the interplay of type I IFN and IL-12 in CD8 T cell responses.

1 reference

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Mousepox, a small animal model of smallpox

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Critical role of perforin-dependent CD8+ T cell immunity for rapid protective vaccination in a murine model for human smallpox

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Modified vaccinia virus Ankara can activate NF-kappaB transcription factors through a double-stranded RNA-activated protein kinase (PKR)-dependent pathway during the early phase of virus replication

1 reference

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Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memory

1 reference

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Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome

1 reference

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6 July 2018

Modified vaccinia virus ankara triggers chemotaxis of monocytes and early respiratory immigration of leukocytes by induction of CCL2 expression

1 reference

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Mousepox in the C57BL/6 strain provides an improved model for evaluating anti-poxvirus therapies

1 reference

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6 July 2018

Postexposure immunization with modified vaccinia virus Ankara or conventional Lister vaccine provides solid protection in a murine model of human smallpox

1 reference

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6 July 2018

Rapid protection in a monkeypox model by a single injection of a replication-deficient vaccinia virus

1 reference

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6 July 2018

Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection

1 reference

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6 July 2018

Requirements for CD8 T-cell priming, memory generation and maintenance

1 reference

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6 July 2018

Recombinant viral vectors: cancer vaccines

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6 July 2018

Signals required for programming effector and memory development by CD8+ T cells

1 reference

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Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

1 reference

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Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines

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Highly attenuated smallpox vaccine protects mice with and without immune deficiencies against pathogenic vaccinia virus challenge

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Replication of modified vaccinia virus Ankara in primary chicken embryo fibroblasts requires expression of the interferon resistance gene E3L.

1 reference

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Signal 3 determines tolerance versus full activation of naive CD8 T cells: dissociating proliferation and development of effector function

1 reference

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Identification of vaccinia virus epitope-specific HLA-A*0201-restricted T cells and comparative analysis of smallpox vaccines.

1 reference

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The roles of IL-12 in providing a third signal for clonal expansion of naive CD8 T cells

1 reference

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Biology of attenuated modified vaccinia virus Ankara recombinant vector in mice: virus fate and activation of B- and T-cell immune responses in comparison with the Western Reserve strain and advantages as a vaccine

1 reference

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Type 1 and type 2 cytokines in antiviral defense.

1 reference

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Modified vaccinia virus Ankara undergoes limited replication in human cells and lacks several immunomodulatory proteins: implications for use as a human vaccine

1 reference

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The complete genomic sequence of the modified vaccinia Ankara strain: comparison with other orthopoxviruses

1 reference

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Different roles for CD4+ and CD8+ T lymphocytes and macrophage subsets in the control of a generalized virus infection

1 reference

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Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara.

1 reference

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Highly attenuated poxviruses induce functional priming of neutrophils in vitro

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6 July 2018

Importance of interferons in recovery from mousepox

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Interferon induction in peripheral blood mononuclear leukocytes of man and farm animals by poxvirus vector candidates and some poxvirus constructs

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Crosstalk between the type 1 interferon and nuclear factor kappa B pathways confers resistance to a lethal virus infection.

1 reference

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Concomitant type I IFN receptor-triggering of T cells and of DC is required to promote maximal modified vaccinia virus Ankara-induced T-cell expansion

1 reference

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Recruitment of antigen-specific CD8+ T cells in response to infection is markedly efficient

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Modified vaccinia virus Ankara induces Toll-like receptor-independent type I interferon responses

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Short-term, but not post-exposure, protection against lethal orthopoxvirus challenge after immunization with modified vaccinia virus Ankara

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Programmed contraction of CD8(+) T cells after infection

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The CD8 response on autopilot

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Dynamic programming of CD8+ T lymphocyte responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/25008931

12 December 2020

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10.1128/JVI.00945-14

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25008931%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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Europe PubMed Central

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11 June 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25008931%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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