Zinc finger nucleases for targeted mutagenesis and repair of the sickle-cell disease mutation: An in-silico study (Q34268053)

1 August 2017

title

Zinc finger nucleases for targeted mutagenesis and repair of the sickle-cell disease mutation: An in-silico study (English)

1 reference

1 August 2017

0 references

1 reference

Misaki Wayengera

1 reference

1 August 2017

publication date

14 May 2012

1 reference

1 August 2017

1 reference

1 August 2017

1 reference

1 August 2017

1 reference

Creative Commons Attribution 2.0 Generic

1 August 2017

start time

14 May 2012

1 reference

April 2022 Public Data File from Crossref

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

An unbiased genome-wide analysis of zinc-finger nuclease specificity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

p53 Gene repair with zinc finger nucleases optimised by yeast 1-hybrid and validated by Solexa sequencing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Genome editing with engineered zinc finger nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

An up-date on the prevalence of sickle cell trait in Eastern and Western Uganda

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Directed evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

ZiFiT (Zinc Finger Targeter): an updated zinc finger engineering tool

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Recent advances in lentiviral vector development and applications

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Bone marrow transplantation (BMT) and gene replacement therapy (GRT) in sickle cell anemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Zinc-finger nucleases: the next generation emerges

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

The sickle cell crisis: a dilemma in pain relief

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Pain management for sickle cell disease in children and adults

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Gene targeting using zinc finger nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Mortality from sickle cell disease in Africa

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Selective inhibition of beta-globin RNA transcripts by antisense RNA molecules.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Repairing the Sickle Cell mutation. II. Effect of psoralen linker length on specificity of formation and yield of third strand-directed photoproducts with the mutant target sequence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

In vivo gene repair of point and frameshift mutations directed by chimeric RNA/DNA oligonucleotides and modified single-stranded oligonucleotides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Peculiar elongated and sickle-shaped red blood corpuscles in a case of severe anemia. 1910

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Beta globin gene inhibition by antisense RNA transcripts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Gene therapy: repairing haemoglobin disorders with ribozymes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Recombinant human parvovirus B19 vectors: erythroid cell-specific delivery and expression of transduced genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Perspectives series: cell adhesion in vascular biology. Adhesive interactions of sickle erythrocytes with endothelium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

The crystal structure of human deoxyhaemoglobin at 1.74 A resolution

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Structure of human oxyhaemoglobin at 2.1 A resolution

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

The biochemistry of resistance to malaria

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Correction of a human beta S-globin gene by gene targeting

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

A third quaternary structure of human hemoglobin A at 1.7-A resolution

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407482

Genetic correction of sickle cell disease: insights using transgenic mouse models

6 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2326-12-5

PECULIAR ELONGATED AND SICKLE-SHAPED RED BLOOD CORPUSCLES IN A CASE OF SEVERE ANEMIA

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2326-12-5

Contribution of sickle cell disease to the occurrence of developmental disabilities: a population-based study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2326-12-5

Bone marrow transplantation for sickle cell disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2326-12-5

Ribozyme-mediated repair of sickle beta-globin mRNAs in erythrocyte precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2326-12-5

Anti-beta s-ribozyme reduces beta s mRNA levels in transgenic mice: potential application to the gene therapy of sickle cell anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2326-12-5

A simple disease with no cure

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2326-12-5

Clinical, hematological, and biochemical features of Hb SC disease

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22583379

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Impact of bone marrow transplantation for symptomatic sickle cell disease: an interim report. Multicenter investigation of bone marrow transplantation for sickle cell disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22583379

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Management of sickle cell disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22583379

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2326-12-5

1 reference

Dimensions Publication ID

1 August 2017

0 references

1 reference

1 August 2017

1 reference