Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling (Q34258498)

31 July 2017

title

Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling (English)

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31 July 2017

main subject

stem cell homeostasis

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1 reference

31 July 2017

Marc van de Wetering

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31 July 2017

Simon Buczacki

0 references

Daniel E Stange

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Kim B Jensen

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Nicholas A Wright

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Hans Clevers

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31 July 2017

Vivian W Y Wong

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31 July 2017

Mahalia E Page

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31 July 2017

Agnieszka Wabik

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31 July 2017

Satoshi Itami

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31 July 2017

Richard Poulsom

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31 July 2017

Matthew W B Trotter

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31 July 2017

Doug J Winton

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31 July 2017

publication date

4 March 2012

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31 July 2017

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

401-408

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describes a project that uses

31 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3378643/fullTextXML

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3378643

inferred from PubMed Central ID database lookup

cites work

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A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable

6 July 2018

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EGF signaling regulates the proliferation of intestinal stem cells in Drosophila

6 July 2018

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Sorting mouse jejunal epithelial cells with CD24 yields a population with characteristics of intestinal stem cells

6 July 2018

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EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila

6 July 2018

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Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

6 July 2018

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A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs

6 July 2018

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Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium

6 July 2018

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Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis

6 July 2018

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Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

6 July 2018

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Transcription factor achaete scute-like 2 controls intestinal stem cell fate

6 July 2018

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Bmi1 is expressed in vivo in intestinal stem cells

6 July 2018

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6 July 2018

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Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF.

6 July 2018

1 reference

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Identification of stem cells in small intestine and colon by marker gene Lgr5

6 July 2018

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6 July 2018

1 reference

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LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy

6 July 2018

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Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence

6 July 2018

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6 July 2018

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6 July 2018

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Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

6 July 2018

1 reference

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Wnt signalling induces maturation of Paneth cells in intestinal crypts

6 July 2018

1 reference

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The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378643

LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation

6 July 2018

1 reference

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6 July 2018

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6 July 2018

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Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia

6 July 2018

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6 July 2018

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6 July 2018

1 reference

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6 July 2018

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Intestinal stem cell replacement follows a pattern of neutral drift

21 January 2018

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21 January 2018

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Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

21 January 2018

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21 January 2018

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Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine

28 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22388892

12 December 2020

inferred from PubMed ID database lookup

Effect of reduced EGFR function on the radiosensitivity and proliferative capacity of mouse jejunal crypt clonogens

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22388892

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCB2464

1 reference

Dimensions Publication ID

31 July 2017

1005449983

0 references

Fatcat ID

release_tp3e4su3qfg3doigiqsyirnq6q

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tp3e4su3qfg3doigiqsyirnq6q

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3378643

1 reference

31 July 2017

1 reference