A quantitative high-throughput 96-well plate fluorescence assay for mechanism-based inactivators of cytochromes P450 exemplified using CYP2B6 (Q34256839)

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scientific article published on September 23, 2010

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English	A quantitative high-throughput 96-well plate fluorescence assay for mechanism-based inactivators of cytochromes P450 exemplified using CYP2B6	scientific article published on September 23, 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

A quantitative high-throughput 96-well plate fluorescence assay for mechanism-based inactivators of cytochromes P450 exemplified using CYP2B6 (English)

1 reference

10.1038/NPROT.2010.125

https://api.crossref.org/works/10.1038/NPROT.2010.125

24 July 2024

cytochrome P-450 enzyme inhibitors

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20885377

24 July 2024

author name string

Cesar Kenaan

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Haoming Zhang

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Paul F. Hollenberg

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20885377

24 July 2024

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National Center for Biotechnology Information

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20885377

24 July 2024

publication date

23 September 2010

1 reference

Europe PubMed Central

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31 July 2017

full work available at URL

https://europepmc.org/articles/pmc2967228?pdf=render

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20885377

24 July 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20885377/?tool=EBI

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20885377

24 July 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20885377/pdf/?tool=EBI

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20885377

24 July 2024

https://europepmc.org/articles/PMC2967228

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Europe PubMed Central

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20885377

24 July 2024

https://europepmc.org/articles/PMC2967228?pdf=render

online access status

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Europe PubMed Central

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20885377

24 July 2024

https://doi.org/10.1038/nprot.2010.125

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20885377

24 July 2024

http://www.nature.com/articles/nprot.2010.125.pdf

1 reference

10.1038/NPROT.2010.125

https://api.crossref.org/works/10.1038/NPROT.2010.125

24 July 2024

http://www.nature.com/articles/nprot.2010.125

1 reference

10.1038/NPROT.2010.125

https://api.crossref.org/works/10.1038/NPROT.2010.125

24 July 2024

Nature Protocols

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1652-1658

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Mechanism-based inactivation of human cytochromes p450s: experimental characterization, reactive intermediates, and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967228

6 July 2018

A real-time fluorescence assay for measuring N-dealkylation

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6 July 2018

Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967228

6 July 2018

Summary of information on human CYP enzymes: human P450 metabolism data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967228

6 July 2018

Mechanism-based inactivators as probes of cytochrome P450 structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967228

6 July 2018

Pharmacogenomics: translating functional genomics into rational therapeutics

1 reference

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6 July 2018

Grapefruit juice-drug interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967228

6 July 2018

Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967228

6 July 2018

Cytochrome P-450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967228

6 July 2018

P450 active site architecture and reversibility: inactivation of cytochromes P450 2B4 and 2B4 T302A by tert-butyl acetylenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967228

28 October 2018

The grapefruit juice effect is not limited to cytochrome P450 (P450) 3A4: evidence for bergamottin-dependent inactivation, heme destruction, and covalent binding to protein in P450s 2B6 and 3A5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967228

28 October 2018

A truncation of 2B subfamily cytochromes P450 yields increased expression levels, increased solubility, and decreased aggregation while retaining function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967228

28 October 2018

A highly sensitive tool for the assay of cytochrome P450 enzyme activity in rat, dog and man. Direct fluorescence monitoring of the deethylation of 7-ethoxy-4-trifluoromethylcoumarin

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2010.125

31 March 2020

A direct, highly sensitive assay for cytochrome P-450 catalyzed O-deethylation using a novel coumarin analog

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2010.125

31 March 2020

Baculovirus vectors: novel mammalian cell gene-delivery vehicles and their applications

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2010.125

31 March 2020

Grapefruit-felodipine interaction: effect of unprocessed fruit and probable active ingredients

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2010.125

31 March 2020

Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20885377

12 December 2020

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Drug Metabolism and Disposition

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1228

author name string

P Schmiedlin-Ren

publication date

1997

1 reference

10.1038/NPROT.2010.125

https://api.crossref.org/works/10.1038/NPROT.2010.125

24 July 2024

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10.1038/NPROT.2010.125

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

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