Metabolomics implicates altered sphingolipids in chronic pain of neuropathic origin. (Q34248884)

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20 January 2020

title

Metabolomics implicates altered sphingolipids in chronic pain of neuropathic origin (English)

1 reference

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20 January 2020

main subject

chronic pain

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chronic neuropathic pain

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20 January 2020

Jean-Philippe Courade

series ordinal

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20 January 2020

1 reference

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20 January 2020

1 reference

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20 January 2020

Gary J Patti

1 reference

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20 January 2020

Leah P Shriver

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20 January 2020

Ralf Tautenhahn

series ordinal

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20 January 2020

publication date

22 January 2012

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20 January 2020

published in

Nature Chemical Biology

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20 January 2020

volume

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20 January 2020

issue

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20 January 2020

page(s)

232-234

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Impaired glial glutamate uptake induces extrasynaptic glutamate spillover in the spinal sensory synapses of neuropathic rats

20 January 2020

cites work

1 reference

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JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain

6 July 2018

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Proteome of synaptosome-associated proteins in spinal cord dorsal horn after peripheral nerve injury

6 July 2018

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Sphingosine 1-phosphate modulates spinal nociceptive processing

6 July 2018

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Principles of bioactive lipid signalling: lessons from sphingolipids

6 July 2018

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The neuropathic pain triad: neurons, immune cells and glia

6 July 2018

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Safingol toxicology after oral administration to TRAMP mice: demonstration of safingol uptake and metabolism by N-acylation and N-methylation

6 July 2018

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The Epidemiology of Chronic Pain of Predominantly Neuropathic Origin. Results From a General Population Survey

6 July 2018

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Biologically active sphingolipids in cancer pathogenesis and treatment

6 July 2018

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Pathways that elicit long-term changes in gene expression in nociceptive neurons following nerve injury: contributions to neuropathic pain

6 July 2018

1 reference

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Glial activation: a driving force for pathological pain

6 July 2018

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Neuropathic pain: aetiology, symptoms, mechanisms, and management

6 July 2018

1 reference

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N,N-Dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: modulation of cellular levels of sphingosine 1-phosphate and ceramide.

6 July 2018

1 reference

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A specific enhancing effect of N,N-dimethylsphingosine on epidermal growth factor receptor autophosphorylation. Demonstration of its endogenous occurrence (and the virtual absence of unsubstituted sphingosine) in human epidermoid carcinoma A431 cell

6 July 2018

1 reference

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Peripheral nerve injury triggers central sprouting of myelinated afferents

6 July 2018

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Pharmacological sensitivity and gene expression analysis of the tibial nerve injury model of neuropathic pain

6 July 2018

1 reference

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Platelet-activating factor modulates brain sphingomyelin metabolism

21 January 2018

1 reference

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PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide.

21 January 2018

1 reference

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Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling

21 January 2018

1 reference

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Multiple actions of dimethylsphingosine in 1321N1 astrocytes.

21 January 2018

1 reference

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Transganglionic degenerative atrophy in the substantia gelatinosa of the spinal cord after peripheral nerve transection in rhesus monkeys

28 October 2018

1 reference

12 December 2020

Enzymatic synthesis of N,N-dimethyl-sphingosine: demonstration of the sphingosine: N-methyltransferase in mouse brain

1 reference

12 December 2020

Changes in cerebrospinal fluid levels of pro-inflammatory cytokines in CRPS

1 reference

12 December 2020

Genetic impairment of interleukin-1 signaling attenuates neuropathic pain, autotomy, and spontaneous ectopic neuronal activity, following nerve injury in mice

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12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.767

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22267119%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

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20 January 2020

PubMed publication ID

22267119

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22267119%20AND%20SRC:MED&resulttype=core&format=json