Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations (Q34248736)

31 July 2017

title

Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations (English)

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31 July 2017

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31 July 2017

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31 July 2017

Andreas von Deimling

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Uri Tabori

Uri Tabori

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31 July 2017

David Malkin

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Nada Jabado

Nada Jabado

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Jelena Tica

Jelena Tica

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Jonathan D. Wasserman

Jonathan Wasserman

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Thomas Zichner

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Joachim Weischenfeldt

Joachim Weischenfeldt

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Jan O Korbel

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Tobias Rausch

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Marc Zapatka

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Vladimir Benes

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Marc Remke

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Rogier Versteeg

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Jan Koster

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Stefan M Pfister

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Cynthia Hawkins

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31 July 2017

Konstanze Döhner

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31 July 2017

Hartmut Döhner

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31 July 2017

Peter Lichter

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31 July 2017

Marcel Kool

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31 July 2017

Paul A Northcott

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31 July 2017

Andrey Korshunov

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31 July 2017

David T W Jones

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31 July 2017

David Shih

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Andreas E Kulozik

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31 July 2017

Michael D Taylor

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Natalie Jäger

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Adrian M Stütz

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Sabrina Pleier

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31 July 2017

Huriye Cin

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31 July 2017

Elke Pfaff

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Olaf Witt

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31 July 2017

Wolfram Scheurlen

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31 July 2017

Adam Fontebasso

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31 July 2017

Dianna Martin

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31 July 2017

Luca Massimi

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31 July 2017

Diana M Merino

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31 July 2017

Qi Wang

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31 July 2017

Hendrik Witt

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31 July 2017

Sebastian Bender

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31 July 2017

Christian Beck

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31 July 2017

Volkmar Hans

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31 July 2017

Jonathon Blake

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31 July 2017

Cindy Zhang

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31 July 2017

Rinnat Porat

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Lars Bullinger

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Frank G Rücker

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31 July 2017

Jan J Molenaar

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31 July 2017

language of work or name

English

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publication date

1 January 2012

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31 July 2017

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31 July 2017

volume

148

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31 July 2017

issue

1-2

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31 July 2017

page(s)

59-71

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FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma

31 July 2017

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

6 July 2018

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Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features

6 July 2018

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6 July 2018

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6 July 2018

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Paired-end mapping reveals extensive structural variation in the human genome

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

6 July 2018

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6 July 2018

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Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332216

TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332216

Interfering with resistance to smoothened antagonists by inhibition of the PI3K pathway in medulloblastoma.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332216

Genomic and gene expression signatures of radiation in medulloblastomas after low-dose irradiation in Ptch1 heterozygous mice.

28 October 2018

1 reference

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Novel oncogene amplifications in tumors from a family with Li-Fraumeni syndrome

28 October 2018

1 reference

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Younger age of cancer initiation is associated with shorter telomere length in Li-Fraumeni syndrome.

28 October 2018

1 reference

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Telomere length in peripheral blood cells of germline TP53 mutation carriers is shorter than that of normal individuals of corresponding age

28 October 2018

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12 December 2020

Different outcomes of telomere-dependent anaphase bridges

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12 December 2020

Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germline†

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12 December 2020

Mutations of the TP53 gene in acute myeloid leukemia are strongly associated with a complex aberrant karyotype

1 reference

12 December 2020

Nonhomologous end-joining of site-specific but not of radiation-induced DNA double-strand breaks is reduced in the presence of wild-type p53

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12 December 2020

Cancer genomes evolve by pulverizing single chromosomes

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12 December 2020

Expression of the neurotrophin receptor p75NTR in medulloblastomas is correlated with distinct histological and clinical features: evidence for a medulloblastoma subtype derived from the external granule cell layer

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12 December 2020

10.1016/J.CELL.2011.12.013

Identifiers

DOI

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31 July 2017

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31 July 2017

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