Normalization of blood glucose in diabetic rats with phlorizin treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose transporter gene expression. (Q34237007)

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English	Normalization of blood glucose in diabetic rats with phlorizin treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose transporter gene expression.	scientific article

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22 September 2019

Normalization of blood glucose in diabetic rats with phlorizin treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose transporter gene expression (English)

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22 September 2019

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insulin resistance

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Gerald I. Shulman

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22 September 2019

Ralph A. DeFronzo

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22 September 2019

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B B Kahn

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22 September 2019

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S W Cushman

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22 September 2019

L Rossetti

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22 September 2019

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1 February 1991

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22 September 2019

Journal of Clinical Investigation

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22 September 2019

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22 September 2019

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22 September 2019

561-570

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22 September 2019

Decreases in tubulin and actin gene expression prior to morphological differentiation of 3T3 adipocytes

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28 July 2018

A possible mechanism of insulin resistance in the rat adipose cell in streptozotocin-induced diabetes mellitus. Depletion of intracellular glucose transport systems

1 reference

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28 July 2018

Reversal of insulin resistance in type I diabetes after treatment with continuous subcutaneous insulin infusion

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28 July 2018

Relationship between obesity and maximal insulin-stimulated glucose uptake in vivo and in vitro in Pima Indians

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28 July 2018

Continuous Subcutaneous Insulin Infusion Therapy Decreases Insulin Resistance in Type 1 Diabetes*

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28 July 2018

Insulin treatment reverses the postreceptor defect in adipocyte 3-O-methylglucose transport in type II diabetes mellitus

1 reference

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28 July 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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28 July 2018

Glucose as a regulator of insulin-sensitive hexose uptake in 3T3 adipocytes

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28 July 2018

Proposed mechanism for increased insulin-mediated glucose transport in adipose cells from young, obese Zucker rats. Large intracellular pool of glucose transporters

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28 July 2018

Sequence and structure of a human glucose transporter

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28 July 2018

Glucose deprivation and hexose transporter polypeptides of murine fibroblasts.

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28 July 2018

Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats

1 reference

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28 July 2018

Mechanism for markedly hyperresponsive insulin-stimulated glucose transport activity in adipose cells from insulin-treated streptozotocin diabetic rats. Evidence for increased glucose transporter intrinsic activity

1 reference

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28 July 2018

Glucose and insulin co-regulate the glucose transport system in primary cultured adipocytes. A new mechanism of insulin resistance.

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28 July 2018

Chronic hypoglycemia increases brain glucose transport

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28 July 2018

Biochemical and functional heterogeneity of rat adipocyte glucose transporters

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28 July 2018

Glucose-induced insulin resistance of skeletal-muscle glucose transport and uptake

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28 July 2018

Role of glucose transporters in the cellular insulin resistance of type II non-insulin-dependent diabetes mellitus

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28 July 2018

Reversal of insulin resistance in diabetic rat adipocytes by insulin therapy. Restoration of pool of glucose transporters and enhancement of glucose-transport activity

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28 July 2018

Insulin-regulatable tissues express a unique insulin-sensitive glucose transport protein

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28 July 2018

Regulation of glucose-transporter gene expression by insulin in cultured human fibroblasts

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28 July 2018

Mechanism for enhanced glucose transport response to insulin in adipose cells from chronically hyperinsulinemic rats. Increased translocation of glucose transporters from an enlarged intracellular pool

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28 July 2018

Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein

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28 July 2018

Decreased expression of the insulin-responsive glucose transporter in diabetes and fasting.

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28 July 2018

Differential regulation of two distinct glucose transporter species expressed in 3T3-L1 adipocytes: effect of chronic insulin and tolbutamide treatment

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28 July 2018

Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic rats

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28 July 2018

Pretranslational suppression of an insulin-responsive glucose transporter in rats with diabetes mellitus.

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28 July 2018

Cloning and characterization of the major insulin-responsive glucose transporter expressed in human skeletal muscle and other insulin-responsive tissues

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28 July 2018

Sequence, tissue distribution, and differential expression of mRNA for a putative insulin-responsive glucose transporter in mouse 3T3-L1 adipocytes

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28 July 2018

A glucose transport protein expressed predominately in insulin-responsive tissues

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28 July 2018

Insulin and glucose-dependent regulation of the glucose transport system in the rat L6 skeletal muscle cell line

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28 July 2018

Identification of a novel gene encoding an insulin-responsive glucose transporter protein

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28 July 2018

Molecular cloning and characterization of an insulin-regulatable glucose transporter

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28 July 2018

Correction of chronic hyperglycemia with vanadate, but not with phlorizin, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic skeletal muscle

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28 July 2018

Evidence against altered expression of GLUT1 or GLUT4 in skeletal muscle of patients with obesity or NIDDM.

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28 July 2018

Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats

1 reference

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28 July 2018

Regulation of glucose transporter messenger RNA levels in rat adipose tissue by insulin.

1 reference

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28 July 2018

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28 July 2018

Development of hormone receptors and hormone responsiveness in vitro. Effect of prolonged insulin treatment on hexose uptake in 3T3-L1 adipocytes

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28 July 2018

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28 July 2018

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28 July 2018

Uptake patterns and transport enhancements in cultures of hamster cells deprived of carbohydrates

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28 July 2018

Insulin action and resistance in obesity and noninsulin-dependent type II diabetes mellitus.

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28 October 2018

Characterization of antisera to a synthetic carboxyl-terminal peptide of the glucose transporter protein

1 reference

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28 October 2018

Studies with antipeptide antibody suggest the presence of at least two types of glucose transporter in rat brain and adipocyte.

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Regulation of glucose transporter messenger RNA in insulin-deficient states

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28 October 2018

Recovery of maximal insulin responsiveness and insulin sensitivity after induction of insulin resistance in primary cultured adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1991839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-regulated glucose uptake in rat adipocytes is mediated by two transporter isoforms present in at least two vesicle populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/1991839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-stimulated translocation of glucose transport systems in the isolated rat adipose cell. Time course, reversal, insulin concentration dependency, and relationship to glucose transport activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/1991839

12 December 2020

based on heuristic

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The nature of regulation of hexose transport in cultured mammalian fibroblasts: Aerobic “repressive” control by d-glucosamine

1 reference

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12 December 2020

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Blood-brain glucose transfer: repression in chronic hyperglycemia

1 reference

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12 December 2020

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The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization

1 reference

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12 December 2020

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A simple, rapid, and sensitive method for measuring protein concentration in subcellular membrane fractions prepared by sucrose density ultracentrifugation

1 reference

https://pubmed.ncbi.nlm.nih.gov/1991839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance is a prominent feature of insulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1991839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate regulation of the glucose transport system in rat skeletal muscle. Characterization and kinetic analysis in isolated soleus muscle and skeletal muscle cells in culture

1 reference

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12 December 2020

based on heuristic

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Characterization and expression of human HepG2/erythrocyte glucose-transporter gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/1991839

12 December 2020

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1 reference

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12 December 2020

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

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inferred from PubMed ID database lookup

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