Elucidation of a novel extracellular calcium-binding site on metabotropic glutamate receptor 1{alpha} (mGluR1{alpha}) that controls receptor activation. (Q34236478)

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English	Elucidation of a novel extracellular calcium-binding site on metabotropic glutamate receptor 1{alpha} (mGluR1{alpha}) that controls receptor activation.	scientific article

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9 February 2020

Elucidation of a novel extracellular calcium-binding site on metabotropic glutamate receptor 1{alpha} (mGluR1{alpha}) that controls receptor activation (English)

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9 February 2020

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9 February 2020

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9 February 2020

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Yusheng Jiang

1

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9 February 2020

Hing-Cheung Wong

3

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9 February 2020

Yubin Zhou

4

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9 February 2020

Xue Wang

5

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9 February 2020

Jun Yang

6

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9 February 2020

Edward M Brown

8

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9 February 2020

Jenny J Yang

9

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9 February 2020

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12 August 2010

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9 February 2020

Journal of Biological Chemistry

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9 February 2020

285

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9 February 2020

43

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9 February 2020

33463-33474

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9 February 2020

Multiple Ca(2+)-binding sites in the extracellular domain of the Ca(2+)-sensing receptor corresponding to cooperative Ca(2+) response

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6 July 2018

Towards predicting Ca2+-binding sites with different coordination numbers in proteins with atomic resolution

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6 July 2018

Identification and dissection of Ca(2+)-binding sites in the extracellular domain of Ca(2+)-sensing receptor

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6 July 2018

Structures of the extracellular regions of the group II/III metabotropic glutamate receptors

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6 July 2018

Predicting calcium-binding sites in proteins - a graph theory and geometry approach.

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6 July 2018

A double mutation in the extracellular Ca2+-sensing receptor's venus flytrap domain that selectively disables L-amino acid sensing

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6 July 2018

Closed state of both binding domains of homodimeric mGlu receptors is required for full activity.

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6 July 2018

The role of the calcium-sensing receptor in epidermal differentiation

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6 July 2018

Calcium sensing receptors as integrators of multiple metabolic signals

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6 July 2018

Extracellular Ca2+-sensing receptors--an overview

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6 July 2018

Calcium dependence of native metabotropic glutamate receptor signaling in central neurons

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6 July 2018

Divalent cations modulate the activity of metabotropic glutamate receptors

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A grafting approach to obtain site-specific metal-binding properties of EF-hand proteins

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6 July 2018

Functional identification of Gd3+ binding site of metabotropic glutamate receptor 1alpha

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6 July 2018

Amino acid mutagenesis of the ligand binding site and the dimer interface of the metabotropic glutamate receptor 1. Identification of crucial residues for setting the activated state

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6 July 2018

Three adjacent serines in the extracellular domains of the CaR are required for L-amino acid-mediated potentiation of receptor function

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Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells

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6 July 2018

Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.

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6 July 2018

Reassessment of the Ca2+ sensing property of a type I metabotropic glutamate receptor by simultaneous measurement of inositol 1,4,5-trisphosphate and Ca2+ in single cells.

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Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

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Automated analysis of interatomic contacts in proteins

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6 July 2018

Diversity of calcium signaling by metabotropic glutamate receptors

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6 July 2018

Pharmacology and functions of metabotropic glutamate receptors

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6 July 2018

Assessment of frequency-dependent alterations in the level of extracellular Ca2+ in the synaptic cleft

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Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors

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Molecular tuning of ion binding to calcium signaling proteins

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Metabotropic glutamate receptors: synaptic transmission, modulation, and plasticity.

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Structural Basis for a Ca 2+ -Sensing Function of the Metabotropic Glutamate Receptors

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Cloning and characterization of a bifunctional metabotropic receptor activated by both extracellular calcium and glutamate

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Extracellular calcium controls the dynamic range of neuronal metabotropic glutamate receptor responses.

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Ligand-induced rearrangement of the dimeric metabotropic glutamate receptor 1alpha.

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Statistical analysis of structural characteristics of protein Ca2+-binding sites

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Effects of coexpression with Homer isoforms on the function of metabotropic glutamate receptor 1alpha

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Rational design of a novel calcium-binding site adjacent to the ligand-binding site on CD2 increases its CD48 affinity

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Extracellular Ca2+ sensitivity of mGluR1alpha associated with persistent glutamate response in transfected CHO cells

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12 December 2020

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Metal binding affinity and structural properties of an isolated EF-loop in a scaffold protein

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Probing site-specific calmodulin calcium and lanthanide affinity by grafting

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Identifiers

10.1074/JBC.M110.147033

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20705606%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PMC publication ID

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Europe PubMed Central

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9 February 2020

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Europe PubMed Central

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9 February 2020

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