Immune suppression in cynomolgus monkeys by XPro9523: an improved CTLA4-Ig fusion with enhanced binding to CD80, CD86 and neonatal Fc receptor FcRn (Q34212755)

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English	Immune suppression in cynomolgus monkeys by XPro9523: an improved CTLA4-Ig fusion with enhanced binding to CD80, CD86 and neonatal Fc receptor FcRn	scientific article

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27 February 2020

Immune suppression in cynomolgus monkeys by XPro9523: an improved CTLA4-Ig fusion with enhanced binding to CD80, CD86 and neonatal Fc receptor FcRn (English)

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27 February 2020

David E. Szymkowski

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27 February 2020

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Matthew J Bernett

1

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27 February 2020

Seung Y Chu

2

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27 February 2020

Irene Leung

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27 February 2020

Gregory L Moore

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27 February 2020

Sung-Hyung Lee

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27 February 2020

Erik Pong

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27 February 2020

Hsing Chen

7

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27 February 2020

Sheryl Phung

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27 February 2020

Umesh S Muchhal

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27 February 2020

Holly M Horton

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27 February 2020

Greg A Lazar

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27 February 2020

John R Desjarlais

12

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27 February 2020

publication date

2 April 2013

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27 February 2020

Monoclonal Antibodies

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27 February 2020

5

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27 February 2020

3

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27 February 2020

384-396

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27 February 2020

Affinity and cross-reactivity engineering of CTLA4-Ig to modulate T cell costimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169032

28 July 2018

Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169032

28 July 2018

Subcutaneous abatacept versus intravenous abatacept: a phase IIIb noninferiority study in patients with an inadequate response to methotrexate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169032

28 July 2018

Enhanced antibody half-life improves in vivo activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169032

28 July 2018

Abatacept binds to the Fc receptor CD64 but does not mediate complement-dependent cytotoxicity or antibody-dependent cellular cytotoxicity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169032

28 July 2018

FcRn: the neonatal Fc receptor comes of age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169032

28 July 2018

Increasing the affinity of a human IgG1 for the neonatal Fc receptor: biological consequences.

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28 July 2018

Structural basis for co-stimulation by the human CTLA-4/B7-2 complex

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28 July 2018

CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169032

28 July 2018

Immunosuppressive effects of human CTLA4Ig in a non-human primate model of allogeneic pancreatic islet transplantation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169032

28 July 2018

CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169032

28 July 2018

Collagen-induced arthritis in the BB rat. Prevention of disease by treatment with CTLA-4-Ig

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169032

28 July 2018

Immunobiology of tissue transplantation: a return to the passenger leukocyte concept

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169032

28 July 2018

CTLA-4 is a second receptor for the B cell activation antigen B7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169032

28 July 2018

The origin and mechanism of the allograft reaction

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28 July 2018

The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses

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21 January 2018

Costimulation blockade in autoimmunity and transplantation

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https://api.crossref.org/works/10.4161%2FMABS.23976

21 January 2018

Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties.

1 reference

https://api.crossref.org/works/10.4161%2FMABS.23976

21 January 2018

Neonatal Fc receptor and IgG-based therapeutics

1 reference

https://api.crossref.org/works/10.4161%2FMABS.23976

21 January 2018

Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses

1 reference

https://api.crossref.org/works/10.4161%2FMABS.23976

21 January 2018

Treatment of murine lupus with CTLA4Ig

1 reference

https://api.crossref.org/works/10.4161%2FMABS.23976

21 January 2018

Costimulatory blockade in patients with rheumatoid arthritis: a pilot, dose-finding, double-blind, placebo-controlled clinical trial evaluating CTLA-4Ig and LEA29Y eighty-five days after the first infusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169032

28 October 2018

Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4169032

28 October 2018

Prophylactic administration of abatacept prevents disease and bone destruction in a rat model of collagen-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23549103

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collagen-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23549103

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/MABS.23976

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Europe PubMed Central

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27 February 2020

PMC publication ID

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Europe PubMed Central

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27 February 2020

PubMed publication ID

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Europe PubMed Central

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27 February 2020

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