APOBEC3G-induced hypermutation of human immunodeficiency virus type-1 is typically a discrete "all or nothing" phenomenon (Q34211562)

31 July 2017

title

APOBEC3G-induced hypermutation of human immunodeficiency virus type-1 is typically a discrete "all or nothing" phenomenon (English)

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31 July 2017

Andrew Rambaut

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Andrew Armitage

object named as

Andrew E Armitage

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31 July 2017

Astrid K N Iversen

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31 July 2017

Andrew James McMichael

object named as

Andrew McMichael

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31 July 2017

Lars Fugger

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31 July 2017

Jan Gerstoft

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31 July 2017

Koen Deforche

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31 July 2017

Chih-Hao Chang

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31 July 2017

Edmund Wee

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31 July 2017

Beatrice Kramer

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31 July 2017

John J Welch

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31 July 2017

publication date

22 March 2012

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31 July 2017

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

e1002550

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Creative Commons Attribution 4.0 International

31 July 2017

start time

22 March 2012

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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Human APOBEC3G-mediated editing can promote HIV-1 sequence diversification and accelerate adaptation to selective pressure

5 July 2018

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Moderate influence of human APOBEC3F on HIV-1 replication in primary lymphocytes

5 July 2018

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5 July 2018

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Analysis of the percentage of human immunodeficiency virus type 1 sequences that are hypermutated and markers of disease progression in a longitudinal cohort, including one individual with a partially defective Vif

5 July 2018

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HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC

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RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1

5 July 2018

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APOBEC3G mRNA expression in exposed seronegative and early stage HIV infected individuals decreases with removal of exposure and with disease progression

5 July 2018

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Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G

5 July 2018

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APOBEC3G inhibits elongation of HIV-1 reverse transcripts

5 July 2018

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5 July 2018

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Evidence of a novel RNA secondary structure in the coding region of HIV-1 pol gene

5 July 2018

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The level of APOBEC3G (hA3G)-related G-to-A mutations does not correlate with viral load in HIV type 1-infected individuals

5 July 2018

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Conserved footprints of APOBEC3G on Hypermutated human immunodeficiency virus type 1 and human endogenous retrovirus HERV-K(HML2) sequences

5 July 2018

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Human immunodeficiency virus (HIV) type 1 proviral hypermutation correlates with CD4 count in HIV-infected women from Kenya

5 July 2018

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Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

5 July 2018

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HLA class I-driven evolution of human immunodeficiency virus type 1 subtype c proteome: immune escape and viral load

5 July 2018

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Cytidine deamination induced HIV-1 drug resistance

5 July 2018

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Human APOBEC3G can restrict retroviral infection in avian cells and acts independently of both UNG and SMUG1

5 July 2018

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Role of APOBEC3G/F-mediated hypermutation in the control of human immunodeficiency virus type 1 in elite suppressors.

5 July 2018

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Target cell APOBEC3C can induce limited G-to-A mutation in HIV-1

5 July 2018

1 reference

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Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B'/C Recombinant (CRF07_BC)

5 July 2018

1 reference

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Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310730

Newly synthesized APOBEC3G is incorporated into HIV virions, inhibited by HIV RNA, and subsequently activated by RNase H

5 July 2018

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Virion-associated uracil DNA glycosylase-2 and apurinic/apyrimidinic endonuclease are involved in the degradation of APOBEC3G-edited nascent HIV-1 DNA

5 July 2018

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Stoichiometry of the antiviral protein APOBEC3G in HIV-1 virions

5 July 2018

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APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G

5 July 2018

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Human APOBEC3 proteins, retrovirus restriction, and HIV drug resistance.

5 July 2018

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MultiCode-RTx real-time PCR system for detection of subpopulations of K65R human immunodeficiency virus type 1 reverse transcriptase mutant viruses in clinical samples

5 July 2018

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Twin gradients in APOBEC3 edited HIV-1 DNA reflect the dynamics of lentiviral replication

5 July 2018

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Transfection of mammalian cells using linear polyethylenimine is a simple and effective means of producing recombinant adeno-associated virus vectors

5 July 2018

1 reference

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Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation

5 July 2018

1 reference

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Functional central polypurine tract provides downstream protection of the human immunodeficiency virus type 1 genome from editing by APOBEC3G and APOBEC3B.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310730

Uracil DNA glycosylase is dispensable for human immunodeficiency virus type 1 replication and does not contribute to the antiviral effects of the cytidine deaminase Apobec3G.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310730

Natural variation in Vif: differential impact on APOBEC3G/3F and a potential role in HIV-1 diversification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310730

Regulatory and accessory HIV-1 proteins: potential targets for HIV-1 vaccines?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310730

G-->A hypermutation in protease and reverse transcriptase regions of human immunodeficiency virus type 1 residing in resting CD4+ T cells in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310730

Cytidine deamination of retroviral DNA by diverse APOBEC proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310730

APOBEC-mediated editing of viral RNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310730

Sequencing-based detection of low-frequency human immunodeficiency virus type 1 drug-resistant mutants by an RNA/DNA heteroduplex generator-tracking assay

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310730

The distribution of fitness effects caused by single-nucleotide substitutions in an RNA virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310730

APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310730

Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310730

Unselected mutations in the human immunodeficiency virus type 1 genome are mostly nonsynonymous and often deleterious

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310730

The causes and consequences of HIV evolution

5 July 2018

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The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310730

DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses

5 July 2018

1 reference

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DNA deamination mediates innate immunity to retroviral infection

5 July 2018

1 reference

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Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts

5 July 2018

1 reference

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The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA

5 July 2018

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5 July 2018

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Relative anti-HIV-1 efficacy of lamivudine and emtricitabine in vitro is dependent on cell type

5 July 2018

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Magnitude and frequency of cytotoxic T-lymphocyte responses: identification of immunodominant regions of human immunodeficiency virus type 1 subtype C.

5 July 2018

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Impaired 2',3'-dideoxy-3'-thiacytidine accumulation in T-lymphoblastoid cells as a mechanism of acquired resistance independent of multidrug resistant protein 4 with a possible role for ATP-binding cassette C11

5 July 2018

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Human immunodeficiency virus type 1 DNA sequences genetically damaged by hypermutation are often abundant in patient peripheral blood mononuclear cells and may be generated during near-simultaneous infection and activation of CD4(+) T cells

5 July 2018

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5 July 2018

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MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs

5 July 2018

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The unusual nucleotide content of the HIV RNA genome results in a biased amino acid composition of HIV proteins

5 July 2018

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Complementation of vif-defective human immunodeficiency virus type 1 by primate, but not nonprimate, lentivirus vif genes

5 July 2018

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Identifiers

DOI

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31 July 2017

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31 July 2017

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