Sept4/ARTS is required for stem cell apoptosis and tumor suppression (Q34206039)

31 July 2017

title

Sept4/ARTS is required for stem cell apoptosis and tumor suppression (English)

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31 July 2017

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Shahin Rafii

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31 July 2017

author name string

María García-Fernández

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31 July 2017

Holger Kissel

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31 July 2017

Samara Brown

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31 July 2017

Travis Gorenc

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31 July 2017

Andrew J Schile

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31 July 2017

Sarit Larisch

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31 July 2017

publication date

1 October 2010

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31 July 2017

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

2282-2293

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p53 regulates hematopoietic stem cell quiescence.

31 July 2017

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5 July 2018

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Regulation of apoptosis by XIAP ubiquitin-ligase activity

5 July 2018

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5 July 2018

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Regulation of apoptosis in Drosophila

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5 July 2018

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Structural insights shed light onto septin assemblies and function.

5 July 2018

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Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.

5 July 2018

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Life and death in hematopoietic stem cells.

5 July 2018

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The cancer stem cell hypothesis: a work in progress

5 July 2018

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A mouse model system to genetically dissect the molecular mechanisms regulating tumorigenesis

5 July 2018

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Metastasis: a question of life or death

5 July 2018

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

5 July 2018

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Diversity of septin scaffolds

5 July 2018

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Promoting apoptosis as a strategy for cancer drug discovery

5 July 2018

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Expression profiling the human septin gene family

5 July 2018

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Apoptosis in Drosophila: neither fish nor fowl (nor man, nor worm).

5 July 2018

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IAPs, RINGs and ubiquitylation

5 July 2018

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Apoptosis-based therapies for hematologic malignancies

5 July 2018

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A mitotic septin scaffold required for Mammalian chromosome congression and segregation

5 July 2018

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The Sept4 septin locus is required for sperm terminal differentiation in mice

5 July 2018

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Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice

5 July 2018

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The pathobiology of the septin gene family

5 July 2018

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Caspase activation, inhibition, and reactivation: a mechanistic view

5 July 2018

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Analysis of mammalian septin expression in human malignant brain tumors

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Mitochondrial pro-apoptotic ARTS protein is lost in the majority of acute lymphoblastic leukemia patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

The mitochondrial ARTS protein promotes apoptosis through targeting XIAP

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Cell death: critical control points

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation.

5 July 2018

1 reference

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Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

5 July 2018

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Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?

5 July 2018

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BIOLOGY OF HEMATOPOIETIC STEM CELLS AND PROGENITORS: Implications for Clinical Application

5 July 2018

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Apoptosis-targeted therapies for cancer

5 July 2018

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5 July 2018

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c-MYC: more than just a matter of life and death

5 July 2018

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IAP proteins: blocking the road to death's door

5 July 2018

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Generation and characterization of Smac/DIABLO-deficient mice.

5 July 2018

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Stem cells, cancer, and cancer stem cells

5 July 2018

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Characterization of XIAP-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Evidence for functional differentiation among Drosophila septins in cytokinesis and cellularization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

5 July 2018

The Hallmarks of Cancer

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The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Programmed cell death in animal development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Increased sensitivity to apoptotic stimuli in c-abl-deficient progenitor B-cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

The septins: roles in cytokinesis and other processes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

The aging of hematopoietic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Genetic control of programmed cell death in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Apoptosis in the pathogenesis and treatment of disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Purification and characterization of mouse hematopoietic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Bcl-2 prevents death of factor-deprived cells but fails to prevent apoptosis in targets of cell mediated killing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Apoptotic cell death induced by c-myc is inhibited by bcl-2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Expression pattern of the septin gene family in acute myeloid leukemias with and without MLL-SEPT fusion genes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Loss of Sept4 exacerbates liver fibrosis through the dysregulation of hepatic stellate cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Characterization of mouse hematopoietic stem and progenitor cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Cell populations during tumorigenesis in Eu-myc transgenic mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Phenotypic and functional characterization of competitive long-term repopulating hematopoietic stem cells enriched from 5-fluorouracil-treated murine marrow

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2956207

Stem Cells and Cancer: Two Faces of Eve

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20952537

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Apoptosis in development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20952537

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20952537

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.1970110

1 reference

31 July 2017

1 reference

31 July 2017

1 reference