Aerobic glycolysis: a novel target in kidney cancer (Q34194088)

31 July 2017

title

Aerobic glycolysis: a novel target in kidney cancer (English)

1 reference

31 July 2017

Brian Shuch

1 reference

31 July 2017

W Marston Linehan

series ordinal

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31 July 2017

Ramaprasad Srinivasan

series ordinal

1 reference

31 July 2017

publication date

1 June 2013

1 reference

Expert Review of Anticancer Therapy

31 July 2017

published in

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

711-719

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Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer

31 July 2017

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species.

5 July 2018

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5 July 2018

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Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

5 July 2018

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Germline SDHB mutations and familial renal cell carcinoma.

5 July 2018

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

5 July 2018

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5 July 2018

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Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

5 July 2018

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5 July 2018

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Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

Akt stimulates aerobic glycolysis in cancer cells

5 July 2018

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5 July 2018

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5 July 2018

1 reference

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5 July 2018

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5 July 2018

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A role for mitochondrial enzymes in inherited neoplasia and beyond

5 July 2018

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Treatment outcome and survival associated with metastatic renal cell carcinoma of non-clear-cell histology

5 July 2018

1 reference

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Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

Localization of a gene (MCUL1) for multiple cutaneous leiomyomata and uterine fibroids to chromosome 1q42.3-q43.

5 July 2018

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Inherited susceptibility to uterine leiomyomas and renal cell cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

Regulation of glut1 mRNA by hypoxia-inducible factor-1. Interaction between H-ras and hypoxia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

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5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

c-Myc transactivation of LDH-A: implications for tumor metabolism and growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

Detection of mitochondrial genome depletion by a novel cDNA in renal cell carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

Identification of the von Hippel-Lindau disease tumor suppressor gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

Mutations of the VHL tumour suppressor gene in renal carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

Cutaneous leiomyomata with uterine leiomyomata

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

The M1- and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma

5 July 2018

1 reference

Hereditary leiomyomatosis and renal cell cancer: a syndrome associated with an aggressive form of inherited renal cancer

21 January 2018

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Mutations in SDHC cause autosomal dominant paraganglioma, type 3.

21 January 2018

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Renal tumors associated with germline SDHB mutation show distinctive morphology.

21 January 2018

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The mammalian target of rapamycin pathway is widely activated without PTEN deletion in renal cell carcinoma metastases.

21 January 2018

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Prognostic relevance of the mTOR pathway in renal cell carcinoma: implications for molecular patient selection for targeted therapy

21 January 2018

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Succinate inhibition of alpha-ketoglutarate-dependent enzymes in a yeast model of paraganglioma

21 January 2018

1 reference

Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.

21 January 2018

1 reference

2-Deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMP-activated protein kinase signaling activation or glycolysis inhibition

21 January 2018

1 reference

Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinib

21 January 2018

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Tumor M2-pyruvate kinase in lung cancer patients: immunohistochemical detection and disease monitoring.

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165485

The morphologic spectrum of kidney tumors in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome

28 October 2018

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12 December 2020

Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc

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12 December 2020

Molecular targeting of VHL gene pathway in clear cell kidney cancer

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12 December 2020

Novel mitochondrial DNA deletion found in a renal cell carcinoma

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12 December 2020

Identifiers

DOI

10.1586/ERA.13.57

1 reference

31 July 2017

1 reference

31 July 2017

1 reference