RRM1-induced metastasis suppression through PTEN-regulated pathways (Q34189695)

31 July 2017

title

RRM1-induced metastasis suppression through PTEN-regulated pathways (English)

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31 July 2017

Ashish Gautam

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31 July 2017

Zhan-Rong Li

series ordinal

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31 July 2017

Gerold Bepler

series ordinal

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31 July 2017

language of work or name

English

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publication date

1 April 2003

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31 July 2017

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

2135-2142

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Defining a novel cis-element in the 3'-untranslated region of mammalian ribonucleotide reductase component R2 mRNA. cis-trans-interactions and message stability

31 July 2017

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The R1 component of mammalian ribonucleotide reductase has malignancy-suppressing activity as demonstrated by gene transfer experiments

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Shc and FAK differentially regulate cell motility and directionality modulated by PTEN.

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

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Suppression of tumorigenicity of A549 lung adenocarcinoma cells by human chromosomes 3 and 11 introduced via microcell-mediated chromosome transfer

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Rho GTPases: signaling, migration, and invasion

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PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

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Overexpression of transfected human ribonucleotide reductase M2 subunit in human cancer cells enhances their invasive potential

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The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast

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DNA-binding activity of wild-type p53 protein is mediated by the central part of the molecule and controlled by its C terminus

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Mammalian ribonucleotide reductase R1 mRNA stability under normal and phorbol ester stimulating conditions: involvement of a cis-trans interaction at the 3' untranslated region

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Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway

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Ribonucleotide reductase: regulation, regulation, regulation

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7 January 2021

Mutation analysis of the PTEN/MMAC1 gene in lung cancer

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7 January 2021

Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

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G proteins and small GTPases: distant relatives keep in touch

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

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Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases

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Reduction and loss of the iron center in the reaction of the small subunit of mouse ribonucleotide reductase with hydroxyurea

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7 January 2021

Lung cancer and the human gene for ribonucleotide reductase subunit M1 (RRM1).

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7 January 2021

From RNA to DNA, why so many ribonucleotide reductases?

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7 January 2021

Tyrosine kinase activity, cytoskeletal organization, and motility in human vascular endothelial cells

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7 January 2021

Multicolor Spectral Karyotyping of Human Chromosomes

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7 January 2021

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

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7 January 2021

Ribonucleotide reductases in the twenty-first century

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7 January 2021

PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

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7 January 2021

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

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7 January 2021

A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

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7 January 2021

Allelotyping demonstrates common and distinct patterns of chromosomal loss in human lung cancer types

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7 January 2021

PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways

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7 January 2021

Nonrandom structural and numerical chromosome changes in non-small-cell lung cancer

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7 January 2021

Transcript map and complete genomic sequence for the 310 kb region of minimal allele loss on chromosome segment 11p15.5 in non-small-cell lung cancer

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206232

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Dimensions Publication ID

31 July 2017

1000115834

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