Predicting the three-dimensional structure of the human facilitative glucose transporter glut1 by a novel evolutionary homology strategy: insights on the molecular mechanism of substrate migration, and binding sites for glucose and inhibitory molecu (Q34187609)

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English	Predicting the three-dimensional structure of the human facilitative glucose transporter glut1 by a novel evolutionary homology strategy: insights on the molecular mechanism of substrate migration, and binding sites for glucose and inhibitory molecu	scientific article

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31 December 2019

Predicting the three-dimensional structure of the human facilitative glucose transporter glut1 by a novel evolutionary homology strategy: insights on the molecular mechanism of substrate migration, and binding sites for glucose and inhibitory molecules (English)

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31 December 2019

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Alexis Salas-Burgos

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31 December 2019

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Pavel Iserovich

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31 December 2019

Felipe Zuniga

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31 December 2019

Juan Carlos Vera

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31 December 2019

Jorge Fischbarg

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23 August 2004

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31 December 2019

Biophysical Journal

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31 December 2019

87

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31 December 2019

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31 December 2019

2990-2999

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31 December 2019

xdlMAPMAN and xdlDATAMAN - programs for reformatting, analysis and manipulation of biomacromolecular electron-density maps and reflection data sets

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Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine

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Interactions of androgens, green tea catechins and the antiandrogen flutamide with the external glucose-binding site of the human erythrocyte glucose transporter GLUT1.

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Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

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Structure and mechanism of the lactose permease of Escherichia coli

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Imaging the metabolic footprint of Glut1 deficiency on the brain

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Sugar transport through maltoporin of Escherichia coli: role of the greasy slide

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Extending the accuracy limits of prediction for side-chain conformations

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The predicted ATP-binding domains in the hexose transporter GLUT1 critically affect transporter activity

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Functional consequences of the autosomal dominant G272A mutation in the human GLUT1 gene

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Sugar transporter regulation by ATP and quaternary structure

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Mutational analysis of GLUT1 (SLC2A1) in Glut-1 deficiency syndrome

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5 July 2018

ATP-dependent substrate occlusion by the human erythrocyte sugar transporter

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5 July 2018

Cysteine-scanning mutagenesis of transmembrane segment 7 of the GLUT1 glucose transporter

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5 July 2018

A conserved amino acid motif (R-X-G-R-R) in the Glut1 glucose transporter is an important determinant of membrane topology

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Defective glucose transport across brain tissue barriers: a newly recognized neurological syndrome

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Major facilitator superfamily

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QLS motif in transmembrane helix VII of the glucose transporter family interacts with the C-1 position of D-glucose and is involved in substrate selection at the exofacial binding site

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5 July 2018

Identification of an Amino Acid Residue That Lies between the Exofacial Vestibule and Exofacial Substrate-binding Site of the Glut1 Sugar Permeation Pathway

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5 July 2018

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5 July 2018

Proposed structure of putative glucose channel in GLUT1 facilitative glucose transporter

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5 July 2018

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Mammalian passive glucose transporters: members of an ubiquitous family of active and passive transport proteins

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5 July 2018

A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport

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Comparative protein modelling by satisfaction of spatial restraints

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

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Barbiturates inhibit hexose transport in cultured mammalian cells and human erythrocytes and interact directly with purified GLUT-1.

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Sequence and structure of a human glucose transporter

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Equilibrium ligand binding to the human erythrocyte sugar transporter. Evidence for two sugar-binding sites per carrier

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Facilitated diffusion of glucose

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Defective Glucose Transport across the Blood-Brain Barrier as a Cause of Persistent Hypoglycorrhachia, Seizures, and Developmental Delay

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Amino acid substitutions at tryptophan 388 and tryptophan 412 of the HepG2 (Glut1) glucose transporter inhibit transport activity and targeting to the plasma membrane in Xenopus oocytes

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28 October 2018

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Autosomal dominant glut-1 deficiency syndrome and familial epilepsy

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A three-dimensional model of the human facilitative glucose transporter Glut1.

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28 October 2018

Cysteine scanning mutagenesis of helices 2 and 7 in GLUT1 identifies an exofacial cleft in both transmembrane segments

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Glutamine 161 of Glut1 glucose transporter is critical for transport activity and exofacial ligand binding.

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28 October 2018

The role of N-glycosylation of GLUT1 for glucose transport activity

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modeling facilitative sugar transporters: transitions between single and double ligand occupancy of multiconformational channel models explain anomalous kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/15326030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tryptophan 388 in putative transmembrane segment 10 of the rat glucose transporter Glut1 is essential for glucose transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/15326030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of adenylate cyclase and inhibition of glucose transport in rat adipocytes by forskolin analogues: structural determinants for distinct sites of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/15326030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GLUT 1: identification of exofacial lysine-residues

1 reference

https://pubmed.ncbi.nlm.nih.gov/15326030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human erythrocyte sugar transporter is also a nucleotide binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15326030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that protein kinase C is involved in regulating glucose transport in the adipocyte

1 reference

https://pubmed.ncbi.nlm.nih.gov/15326030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1529/BIOPHYSJ.104.047886

1 reference

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31 December 2019

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Europe PubMed Central

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31 December 2019

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Europe PubMed Central

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31 December 2019

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