Vitamin C as an antioxidant: evaluation of its role in disease prevention (Q34175262)

31 July 2017

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title

Vitamin C as an antioxidant: evaluation of its role in disease prevention (English)

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31 July 2017

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Peter Eck

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Christopher Peter Corpe

object named as

Christopher Corpe

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author name string

Sebastian J Padayatty

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31 July 2017

Arie Katz

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31 July 2017

Yaohui Wang

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31 July 2017

Oran Kwon

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31 July 2017

Je-Hyuk Lee

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31 July 2017

Shenglin Chen

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31 July 2017

Anand Dutta

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31 July 2017

Sudhir K Dutta

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31 July 2017

Mark Levine

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31 July 2017

publication date

1 February 2003

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Journal of the American College of Nutrition

31 July 2017

published in

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

18-35

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Some properties of the ascorbate free radical

31 July 2017

cites work

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The biosynthesis of neuropeptides: peptide alpha-amidation

21 January 2018

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The biochemical functions of ascorbic acid

21 January 2018

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The mechanism of enzymic formation of homogentisate from p-hydroxyphenylpyruvate

21 January 2018

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The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate

21 January 2018

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The isoprostanes: their quantification as an index of oxidant stress status in vivo

21 January 2018

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Low Density Lipoprotein Oxidation and Its Pathobiological Significance

21 January 2018

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The oxidative modification hypothesis of atherosclerosis: does it hold for humans?

21 January 2018

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Protein Oxidation in Aging, Disease, and Oxidative Stress

21 January 2018

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Quantification and significance of protein oxidation in biological samples

21 January 2018

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Reactive oxygen-mediated protein oxidation in aging and disease

21 January 2018

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The role of AGEs in aging: causation or correlation

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Vitamin C and genomic stability

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

NO-induced oxidative stress and glutathione metabolism in rodent and human cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Vitamins as antimutagens: advantages and some possible mechanisms of antimutagenic action

21 January 2018

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DNA deaminating ability and genotoxicity of nitric oxide and its progenitors

21 January 2018

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DNA damage and mutation in human cells exposed to nitric oxide in vitro

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

5-A-DAY: dietary behavior and the fruit and vegetable intake of Latino children.

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance

21 January 2018

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21 January 2018

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Cloning and functional characterization of the human sodium-dependent vitamin C transporters hSVCT1 and hSVCT2

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

A family of mammalian Na+-dependent L-ascorbic acid transporters

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Physiologic levels of ascorbate inhibit the oxidative modification of low density lipoprotein

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Preservation of the endogenous antioxidants in low density lipoprotein by ascorbate but not probucol during oxidative modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Influence of antioxidant vitamins on LDL oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Is the emperor wearing clothes? Clinical trials of vitamin E and the LDL oxidation hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Antioxidant defenses and lipid peroxidation in human blood plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Ascorbate is an outstanding antioxidant in human blood plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Formation of non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in plasma and low density lipoprotein exposed to oxidative stress in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Lipid hydroperoxide modification of proteins during myocardial ischaemia

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Circulating oxidized LDL is a useful marker for identifying patients with coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Oxidation of low density lipoproteins in the pathogenesis of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Autoantibodies to oxidized low-density lipoprotein in patients with type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

The effect of vitamin C on in vivo lipid peroxidation in guinea pigs as measured by pentane and ethane production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Lewis A. Conner Memorial Lecture. Oxidative modification of LDL and atherogenesis

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

The oxidative modification hypothesis of atherogenesis: an overview

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Nitric oxide and peroxynitrite. The ugly, the uglier and the not so good: a personal view of recent controversies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Alteration of aminoacyl-tRNA synthetase with age: heat-labilization of the enzyme by oxidative damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Cigarette smoke oxidation of human plasma constituents

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Modification of plasma proteins by cigarette smoke as measured by protein carbonyl formation

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Efficacy of hypochlorous acid scavengers in the prevention of protein carbonyl formation.

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Carbonic anhydrase III. Oxidative modification in vivo and loss of phosphatase activity during aging

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Mitochondrial adenine nucleotide translocase is modified oxidatively during aging

21 January 2018

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https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

A hydroxyl radical-like species oxidizes cynomolgus monkey artery wall proteins in early diabetic vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Oxidative stress increases production of beta-amyloid precursor protein and beta-amyloid (Abeta) in mammalian lenses, and Abeta has toxic effects on lens epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Nutritional influences on risk for cataract

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Cupric ion/ascorbate/hydrogen peroxide-induced DNA damage: DNA-bound copper ion primarily induces base modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Sodium ascorbate induces DNA single-strand breaks in human cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

DNA damage from micronutrient deficiencies is likely to be a major cause of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Oxidative DNA damage estimated by oxo8dG in the liver of guinea-pigs supplemented with graded dietary doses of ascorbic acid and alpha-tocopherol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Quantification of 8-oxo-guanine and guanine as the nucleobase, nucleoside and deoxynucleoside forms in human urine by high-performance liquid chromatography-electrospray tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Inhibition of N-nitrosation of secondary amines in vitro by tea extracts and catechins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Loss of heterozygosity in (LewisxF344)F1 rat urinary bladder tumors induced with N-butyl-N-(4-hydroxybutyl)nitrosamine followed by dimethylarsinic acid or sodium L-ascorbate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Glycoxidation and lipoxidation in atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Coronary artery disease--free radical damage, antioxidant protection and the role of homocysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Pathophysiology of oxidative stress in diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Antioxidants, NFkappaB activation, and diabetogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Oxidative stress and haemodialysis: role of inflammation and duration of dialysis treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

The contribution of hypoxia-reperfusion injury to inflammatory synovitis: the influence of reactive oxygen intermediates on the transcriptional control of inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Endothelial dysfunction in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Ascorbate restores endothelium-dependent vasodilation impaired by acute hyperglycemia in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

L-2-Oxothiazolidine-4-carboxylic acid reverses endothelial dysfunction in patients with coronary artery disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Vitamin C and blood pressure–an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Does vitamin C reduce blood pressure? Results of a large study of people aged 65 or older

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Effect of vitamin C on ambulatory blood pressure and plasma lipids in older persons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Dietary supplement with vitamin C prevents nitrate tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Is there a physiological role of vitamin C in iron absorption?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Ascorbic acid: a factor concentrated in human gastric juice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Effect of eradication of Helicobacter pylori on gastric juice ascorbic acid concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

High gastric juice ascorbic acid concentrations in members of a gastric cancer family

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Influence of fruit and vegetable juices on the endogenous formation of N-nitrosoproline and N-nitrosothiazolidine-4-carboxylic acid in humans on controlled diets

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Plasma levels and redox status of ascorbic acid and levels of lipid peroxidation products in active and passive smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Leucocyte ascorbic acid levels after acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Vitamin C status in patients with acute pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Dietary antioxidants and carotid artery wall thickness. The ARIC Study. Atherosclerosis Risk in Communities Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Fruit and vegetable intake in relation to risk of ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Fruit and vegetables, and cardiovascular disease: a review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Dietary vitamin C, beta-carotene and 30-year risk of stroke: results from the Western Electric Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

The effect of fruit and vegetable intake on risk for coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Relation of consumption of vitamin E, vitamin C, and carotenoids to risk for stroke among men in the United States.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Serial coronary angiographic evidence that antioxidant vitamin intake reduces progression of coronary artery atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Lowered risks of hypertension and cerebrovascular disease after vitamin/mineral supplementation: the Linxian Nutrition Intervention Trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) study: a randomized trial of the effect of vitamins E and C on 3-year progression of carotid atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Vitamin C and cardiovascular disease: a systematic review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

The antioxidant vitamins and cardiovascular disease. A critical review of epidemiologic and clinical trial data

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

The Roche European American Cataract Trial (REACT): a randomized clinical trial to investigate the efficacy of an oral antioxidant micronutrient mixture to slow progression of age-related cataract

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Plasma antioxidant vitamins and carotenoids and age-related cataract

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Dietary carotenoids and vitamins A, C, and E and risk of breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Which plasma antioxidants are most related to fruit and vegetable consumption?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

F(2)-isoprostanes: sensitive and specific non-invasive indices of lipid peroxidation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Long-term effects of vitamin E, vitamin C, and combined supplementation on urinary 7-hydro-8-oxo-2'-deoxyguanosine, serum cholesterol oxidation products, and oxidation resistance of lipids in nondepleted men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Vitamin C exhibits pro-oxidant properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

Diet and risk of basal cell carcinoma of the skin in a prospective cohort of women

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2003.10719272

10.1080/07315724.2003.10719272

21 January 2018

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DOI

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31 July 2017

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