Inflammatory dendritic cells--not basophils--are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen (Q34161524)

31 July 2017

title

Inflammatory dendritic cells--not basophils--are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen (English)

1 reference

Dermatophagoides pteronyssinus

31 July 2017

main subject

1 reference

1 reference

Hamida Hammad

0 references

Bart N Lambrecht

1 reference

31 July 2017

Monique A M Willart

1 reference

31 July 2017

Kim Deswarte

1 reference

31 July 2017

Maud Plantinga

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31 July 2017

Mirjam Kool

1 reference

31 July 2017

Femke Muskens

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31 July 2017

Philippe Pouliot

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31 July 2017

language of work or name

English

0 references

publication date

6 September 2010

1 reference

Journal of Experimental Medicine

31 July 2017

published in

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31 July 2017

volume

207

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31 July 2017

1 reference

31 July 2017

page(s)

2097-2111

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The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling.

31 July 2017

cites work

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5 July 2018

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Cutting edge: basophils are transiently recruited into the draining lymph nodes during helminth infection via IL-3, but infection-induced Th2 immunity can develop without basophil lymph node recruitment or IL-3.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

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Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma

5 July 2018

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Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

5 July 2018

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5 July 2018

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A mechanism for the initiation of allergen-induced T helper type 2 responses

5 July 2018

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5 July 2018

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5 July 2018

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Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system

5 July 2018

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Syk activation in dendritic cells is essential for airway hyperresponsiveness and inflammation

5 July 2018

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5 July 2018

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In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma

5 July 2018

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5 July 2018

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Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Intratracheal priming with ovalbumin- and ovalbumin 323-339 peptide-pulsed dendritic cells induces airway hyperresponsiveness, lung eosinophilia, goblet cell hyperplasia, and inflammation

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

5 July 2018

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Peripheral blood dendritic cells express Fc epsilon RI as a complex composed of Fc epsilon RI alpha- and Fc epsilon RI gamma-chains and can use this receptor for IgE-mediated allergen presentation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947072

The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules

5 July 2018

1 reference

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Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

5 July 2018

1 reference

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HLA-DM: an in vivo facilitator of MHC class II peptide loading

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947072

Sequence analysis of cDNA coding for a major house dust mite allergen, Der p 1. Homology with cysteine proteases

5 July 2018

1 reference

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5 July 2018

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Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells

5 July 2018

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Cross-linking Fc receptors stimulate splenic non-B, non-T cells to secrete interleukin 4 and other lymphokines

5 July 2018

1 reference

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5 July 2018

1 reference

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Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells.

5 July 2018

1 reference

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Toll/IL-1 signaling is critical for house dust mite-specific helper T cell type 2 and type 17 [corrected] responses.

28 October 2018

1 reference

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Sensitization by intratracheally injected dendritic cells is independent of antigen presentation by host antigen-presenting cells

28 October 2018

1 reference

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Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury

28 October 2018

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Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo

28 October 2018

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Cutting edge: generation of splenic CD8+ and CD8- dendritic cell equivalents in Fms-like tyrosine kinase 3 ligand bone marrow cultures.

28 October 2018

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A critical role for eosinophils in allergic airways remodeling

28 October 2018

1 reference

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Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947072

Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947072

Interleukin-3Ralpha+ myeloid dendritic cells and mast cells develop simultaneously from different bone marrow precursors in cultures with interleukin-3.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947072

Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947072

Th2 polarization by Der p 1--pulsed monocyte-derived dendritic cells is due to the allergic status of the donors

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947072

Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947072

Dendritic cells are required for the development of chronic eosinophilic airway inflammation in response to inhaled antigen in sensitized mice

28 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947072

Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

28 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947072

Cutting edge: Th2 response induction by dendritic cells: a role for CD40

28 October 2018

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12 December 2020

Basophils are essential initiators of a novel type of chronic allergic inflammation

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12 December 2020

Differential development of murine dendritic cells by GM-CSF versus Flt3 ligand has implications for inflammation and trafficking

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12 December 2020

Basophils enhance immunological memory responses

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12 December 2020

A novel role for IL-3: human monocytes cultured in the presence of IL-3 and IL-4 differentiate into dendritic cells that produce less IL-12 and shift Th cell responses toward a Th2 cytokine pattern

1 reference

12 December 2020

Parasite-induced Th2 polarization is associated with down-regulated dendritic cell responsiveness to Th1 stimuli and a transient delay in T lymphocyte cycling

1 reference

12 December 2020

Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites

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12 December 2020

Identifiers

DOI

10.1084/JEM.20101563

1 reference

31 July 2017

1 reference

31 July 2017

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