Cytokines suppress human islet function irrespective of their effects on nitric oxide generation (Q34143253)

31 July 2017

title

Cytokines suppress human islet function irrespective of their effects on nitric oxide generation (English)

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31 July 2017

Sandler S

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31 July 2017

Hellerström C

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31 July 2017

Eizirik DL

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31 July 2017

Welsh N

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31 July 2017

Cetkovic-Cvrlje M

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31 July 2017

Nieman A

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31 July 2017

Geller DA

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31 July 2017

Pipeleers DG

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31 July 2017

Bendtzen K

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31 July 2017

language of work or name

English

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publication date

1 May 1994

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Journal of Clinical Investigation

31 July 2017

published in

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

1968-1974

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Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans

31 July 2017

cites work

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Repair of pancreatic beta-cells. A relevant phenomenon in early IDDM?

5 July 2018

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Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes

5 July 2018

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Interleukin‐1 ‐induced expression of nitric oxide synthase in insulin‐producing cells is preceded by c‐fos induction and depends on gene transcription and protein synthesis

5 July 2018

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5 July 2018

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Type I diabetes mellitus. A chronic autoimmune disease

5 July 2018

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5 July 2018

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Detection of tumour necrosis factor from lipopolysaccharide-stimulated human mononuclear cells by enzyme-linked immunosorbent assay and cytotoxicity bioassay

5 July 2018

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5 July 2018

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Oxygen free radical scavengers protect rat islet cells from damage by cytokines

5 July 2018

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Interleukin-1 beta depletes insulin messenger ribonucleic acid and increases the heat shock protein hsp70 in mouse pancreatic islets without impairing the glucose metabolism

5 July 2018

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Cytokine and free radicals as effector molecules in the destruction of pancreatic beta cells

5 July 2018

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Biochemical and Molecular Actions of Interleukin-1 on Pancreatic β-Cells

5 July 2018

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Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta-cell function

5 July 2018

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Type 1 (insulin-dependent) diabetes mellitus and nitric oxide

5 July 2018

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Does nitric oxide mediate autoimmune destruction of beta-cells? Possible therapeutic interventions in IDDM

5 July 2018

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Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction

5 July 2018

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5 July 2018

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Construction and selection of recombinant plasmids containing full-length complementary DNAs corresponding to rat insulins I and II

5 July 2018

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Some statistical methods useful in circulation research.

5 July 2018

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Viability tests of cryopreserved endocrine pancreatic cells

28 October 2018

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Inhibitor of interleukin 1 in normal human urine. Different effects on mouse thymocytes and on a murine T-cell line

28 October 2018

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12 December 2020

Defective catabolism of D-glucose and L-glutamine in mouse pancreatic islets maintained in culture after streptozotocin exposure

1 reference

12 December 2020

Association between HLA-DR2 and Production of Tumour Necrosis Factor alpha and Interleukin 1 by Mononuclear Cells Activated by Lipopolysaccharide

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12 December 2020

Interleukin-6 affects insulin secretion and glucose metabolism of rat pancreatic islets in vitro

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12 December 2020

Cytotoxic effects of cytokines on human pancreatic islet cells in monolayer culture

1 reference

12 December 2020

Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism

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12 December 2020

Short-term exposure of rat pancreatic islets to human interleukin-1 beta increases cellular uptake of calcium

1 reference

12 December 2020

Cytotoxic effect of IFN-gamma plus TNF-alpha on human islet cells

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12 December 2020

Species differences in human and rat islet sensitivity to human cytokines. Monoclonal anti-interleukin-1 (IL-1) influences on direct and indirect IL-1-mediated islet effects

1 reference

12 December 2020

Interleukin-1 beta-induced formation of EPR-detectable iron-nitrosyl complexes in islets of Langerhans. Role of nitric oxide in interleukin-1 beta-induced inhibition of insulin secretion

1 reference

12 December 2020

Interleukin-lβ-Induced Nitric Oxide Production in Isolated Rat Pancreatic Islets Requires Gene Transcription and May Lead to Inhibition of the Krebs Cycle Enzyme Aconitase*

1 reference

12 December 2020

Interleukin-1β induces nitric oxide production and inhibits the activity of aconitase without decreasing glucose oxidation rates in isolated mouse pancreatic islets

1 reference

12 December 2020

Interleukin-1β Induces an Early Decrease in Insulin Release, (Pro)Insulin Biosynthesis and Insulin Mrna in Mouse Pancreatic Islets by a Mechanism Dependent on Gene Transcription and Protein Synthesis

1 reference

12 December 2020

Cytotoxic effects of cytokines on rat islets: evidence for involvement of free radicals and lipid peroxidation

1 reference

12 December 2020

Interaction of interleukin-1 with islet beta-cells. Distinction between indirect, aspecific cytotoxicity and direct, specific functional suppression

1 reference

12 December 2020

Predominance of stimulatory effects of interleukin-1 beta on isolated human pancreatic islets

1 reference

12 December 2020

Selective inhibition of the inducible nitric oxide synthase by aminoguanidine

1 reference

12 December 2020

Genotoxic agents increase expression of growth arrest and DNA damage--inducible genes gadd 153 and gadd 45 in rat pancreatic islets

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI117188

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31 July 2017

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31 July 2017

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