Selective Targeting of Human Alloresponsive CD8+ Effector Memory T Cells Based on CD2 Expression (Q34149246)

31 July 2017

title

Selective targeting of human alloresponsive CD8+ effector memory T cells based on CD2 expression (English)

1 reference

31 July 2017

Selective Targeting of Human Alloresponsive CD8+ Effector Memory T Cells Based on CD2 Expression (English)

1 reference

https://api.crossref.org/works/10.1111/J.1600-6143.2010.03317.X

24 August 2024

A. K. Mehta

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21070604

24 August 2024

A. D. Kirk

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21070604

24 August 2024

D. J. Lo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21070604

24 August 2024

T. A. Weaver

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21070604

24 August 2024

L. Stempora

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21070604

24 August 2024

M. L. Ford

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21070604

24 August 2024

C. P. Larsen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21070604

24 August 2024

language of work or name

English

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publication date

10 November 2010

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full work available at URL

31 July 2017

https://europepmc.org/articles/pmc3057516?pdf=render

file format

Portable Document Format

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21070604

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21070604/?tool=EBI

24 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21070604

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21070604/pdf/?tool=EBI

24 August 2024

file format

Portable Document Format

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21070604

https://europepmc.org/articles/PMC3057516

24 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21070604

https://europepmc.org/articles/PMC3057516?pdf=render

24 August 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21070604

https://doi.org/10.1111/j.1600-6143.2010.03317.x

24 August 2024

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21070604

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1600-6143.2010.03317.x

24 August 2024

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https://api.crossref.org/works/10.1111/J.1600-6143.2010.03317.X

https://api.elsevier.com/content/article/PII:S1600613522277740?httpAccept=text/xml

24 August 2024

1 reference

https://api.crossref.org/works/10.1111/J.1600-6143.2010.03317.X

https://api.elsevier.com/content/article/PII:S1600613522277740?httpAccept=text/plain

24 August 2024

1 reference

https://api.crossref.org/works/10.1111/J.1600-6143.2010.03317.X

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1600-6143.2010.03317.x/fullpdf

24 August 2024

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https://api.crossref.org/works/10.1111/J.1600-6143.2010.03317.X

American Journal of Transplantation

24 August 2024

published in

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

22-33

1 reference

Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Therapeutic memory T cells require costimulation for effective clearance of a persistent viral infection.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Alefacept in the treatment of psoriasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Donor-reactive CD8 memory T cells infiltrate cardiac allografts within 24-h posttransplant in naive recipients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Safety and efficacy of alefacept, efalizumab, etanercept and infliximab in treating moderate to severe plaque psoriasis: a meta-analysis of randomized controlled trials

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

A critical precursor frequency of donor-reactive CD4+ T cell help is required for CD8+ T cell-mediated CD28/CD154-independent rejection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Alefacept (anti-CD2) causes a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tcm) in psoriasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Multiple-cytokine-producing antiviral CD4 T cells are functionally superior to single-cytokine-producing cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

The impact of memory T cells on rejection and the induction of tolerance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Functional signatures of protective antiviral T-cell immunity in human virus infections.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Heterologous immunity: an overlooked barrier to tolerance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Heterologous immunity provides a potent barrier to transplantation tolerance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

CD2 engagement induces dendritic cell activation: implications for immune surveillance and T-cell activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Pretransplant frequency of donor-specific, IFN-gamma-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Functional differences between memory and naive CD8 T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Involvement of protein tyrosine kinase p72syk and phosphatidylinositol 3-kinase in CD2-mediated granular exocytosis in the natural killer cell line, NK3.3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Lymphocyte-mediated cytotoxicity: two pathways and multiple effector molecules

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Specific interaction of lymphocyte function-associated antigen 3 with CD2 can inhibit T cell responses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

The lymphocyte function-associated LFA-1, CD2, and LFA-3 molecules: cell adhesion receptors of the immune system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

The structural biology of CD2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Phenotypic changes associated with activation of CD45RA+ and CD45RO+ T cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Functional responses and costimulator dependence of memory CD4+ T cells.

5 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2010.03317.X

Four functionally distinct populations of human effector-memory CD8+ T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2010.03317.X

Activated and memory CD8+ T cells can be distinguished by their cytokine profiles and phenotypic markers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2010.03317.X

Development and homeostasis of T cell memory in rhesus macaque

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2010.03317.X

Control of memory CD4 T cell recall by the CD28/B7 costimulatory pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2010.03317.X

Defective alloreactive CD8 T cell function and memory response in allograft recipients in the absence of CD4 help

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2010.03317.X

A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study).

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Contribution of naïve and memory T-cell populations to the human alloimmune response.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Dominant human CD8 T cell clonotypes persist simultaneously as memory and effector cells in memory phase

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Costimulation blockade with belatacept in renal transplantation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Repeat courses of intravenous alefacept in patients with chronic plaque psoriasis provide consistent safety and efficacy

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Primed allospecific T cells prevent the effects of costimulatory blockade on prolonged cardiac allograft survival in mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Role of CD28-B7 interactions in generation and maintenance of CD8 T cell memory

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Treatment of chronic plaque psoriasis by selective targeting of memory effector T lymphocytes.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

A subtle role for CD2 in T cell antigen recognition

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Qualitative differences between naive and memory T cells make a major contribution to the more rapid and efficient memory CD8+ T cell response.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

CTLA4-Ig plus bone marrow induces long-term allograft survival and donor specific unresponsiveness in the murine model. Evidence for hematopoietic chimerism

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

CD2-mediated adhesion facilitates T lymphocyte antigen recognition function

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057516

Cutting Edge: Persistent Viral Infection Prevents Tolerance Induction and Escapes Immune Control Following CD28/CD40 Blockade-Based Regimen

28 October 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2010.03317.X

T cells primed by Leishmania major infection cross-react with alloantigens and alter the course of allograft rejection

21 January 2018

1 reference

12 December 2020

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

1 reference

12 December 2020

Mechanism of lymphocyte function-associated molecule 3-Ig fusion proteins inhibition of T cell responses. Structure/function analysis in vitro and in human CD2 transgenic mice

1 reference

12 December 2020

Expression of CTL associated transcripts precedes the development of tubulitis in T-cell mediated kidney graft rejection

1 reference

12 December 2020

CD2-CD58 Interaction and the Control of T-Cell Interleukin-12 Responsiveness

1 reference

12 December 2020

Human monocytes as intermediaries between allogeneic endothelial cells and allospecific T cells: a role for direct scavenger receptor-mediated endothelial membrane uptake in the initiation of alloimmunity

1 reference

12 December 2020

Low affinity binding of an LFA-3/IgG1 fusion protein to CD2+ T cells is independent of cell activation

1 reference

12 December 2020

Identifiers

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31 July 2017

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31 July 2017

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