Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish (Q34144327)

31 July 2017

title

Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish (English)

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31 July 2017

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GOA release 2020-03-11

Leonard I Zon

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31 July 2017

Michael Dovey

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31 July 2017

Richard Mark White

series ordinal

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31 July 2017

publication date

1 December 2009

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31 July 2017

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

397-404

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ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence

31 July 2017

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5 July 2018

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5 July 2018

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

5 July 2018

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A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility

5 July 2018

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

5 July 2018

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Use of human tissue to assess the oncogenic activity of melanoma-associated mutations

5 July 2018

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Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

5 July 2018

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Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma

5 July 2018

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NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression.

5 July 2018

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High Intensity ras Signaling Induces Premature Senescence by Activating p38 Pathway in Primary Human Fibroblasts

5 July 2018

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How the zebrafish gets its stripes

5 July 2018

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Mutational analysis of the N-ras, p53, p16INK4a, CDK4, and MC1R genes in human congenital melanocytic naevi

5 July 2018

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nacre encodes a zebrafish microphthalmia-related protein that regulates neural-crest-derived pigment cell fate

5 July 2018

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Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

5 July 2018

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Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

5 July 2018

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Germline p16 mutations in familial melanoma

5 July 2018

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ras oncogenes in human cancer: a review

5 July 2018

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Novel genes associated with malignant melanoma but not benign melanocytic lesions

5 July 2018

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BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma.

28 October 2018

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Real-time quantitative PCR-based system for determining transgene copy number in transgenic animals.

28 October 2018

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Analysis of N- and K-ras mutations in the distinctive tumor progression phases of melanoma.

28 October 2018

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Metastasizing Melanoma Formation Caused by Expression of Activated N-RasQ61Kon an INK4a-Deficient Background

28 October 2018

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Analysis of ras oncogenes in malignant melanoma and precursor lesions: correlation of point mutations with differentiation phenotype

28 October 2018

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12 December 2020

Analysis of ras mutations in human melanocytic lesions: activation of the ras gene seems to be associated with the nodular type of human malignant melanoma

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12 December 2020

N-ras mutations are common in melanomas from sun-exposed skin of humans but rare in mucosal membranes or unexposed skin

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12 December 2020

Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression

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12 December 2020

Identifiers

DOI

10.1089/ZEB.2009.0606

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31 July 2017

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31 July 2017

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