Transgenic mouse models of human breast cancer (Q34130558)

31 July 2017

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title

Transgenic mouse models of human breast cancer (English)

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31 July 2017

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Hutchinson JN

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31 July 2017

Muller WJ

series ordinal

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31 July 2017

language of work or name

English

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publication date

1 December 2000

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31 July 2017

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

6130-6137

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Overexpression of HER-2/neu and its relationship with other prognostic factors change during the progression of in situ to invasive breast cancer

31 July 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

The neu oncogene encodes an epidermal growth factor receptor-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Prognostic factors in human primary breast cancer: comparison of c-myc and HER2/neu amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Genetic alterations in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Prolactin controls mammary gland development via direct and indirect mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Somatic mutations and human breast cancer. A status report

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Ligands for ErbB-family receptors encoded by a neuregulin-like gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Signal transduction in mammary tumorigenesis: a transgenic perspective

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Tumorigenesis by mouse mammary tumor virus: Proviral activation of a cellular gene in the common integration region int-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

The p53 tumor suppressor gene in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Protein-tyrosine phosphatase epsilon. An isoform specifically expressed in mouse mammary tumors initiated by v-Ha-ras OR neu.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Impaired mammary gland development in Cyl-1(-/-) mice during pregnancy and lactation is epithelial cell autonomous

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Activated neu induces rapid tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Transforming growth factor alpha and mouse models of human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Increased tumor proliferation and genomic instability without decreased apoptosis in MMTV-ras mice deficient in p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

The mutationally activated Met receptor mediates motility and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Preferential activation of Fgf8 by proviral insertion in mammary tumors of Wnt1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

A novel splice variant of HER2 with increased transformation activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Consequences of widespread deregulation of the c-myc gene in transgenic mice: multiple neoplasms and normal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

A transgenic mouse model for mammary carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Transgenic expression of tpr-met oncogene leads to development of mammary hyperplasia and tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Genetic variability of proto-oncogenes for breast cancer risk and prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Synergistic interaction of the Neu proto-oncogene product and transforming growth factor alpha in the mammary epithelium of transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

The ErbB signaling network: receptor heterodimerization in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

BRCA1: a review of structure and putative functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

HER-2/neu as a predictive marker of response to breast cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Tumorigenesis by mouse mammary tumor virus: Evidence for a common region for provirus integration in mammary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Mouse mammary tumor virus/v-Ha- ras transgene-induced mammary tumors exhibit strain-specific allelic loss on mouse chromosome 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

The c-erbB-2 proto-oncogene as a prognostic and predictive marker in breast cancer: A paradigm for the development of other macromolecular markers-A review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Inducible gene targeting in mice using the Cre/lox system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Mutations affecting conserved cysteine residues within the extracellular domain of Neu promote receptor dimerization and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

An activated allele of the c-erbB-2 oncogene impairs kidney and lung function and causes early death of transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

The role of prolactin and growth hormone in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

Epidemiology, prevention, and early detection of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

neu/erbB-2 amplification identifies a poor-prognosis group of women with node-negative breast cancer. Toronto Breast Cancer Study Group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

Gene amplification and tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

MMTV-Fgf8 transgenic mice develop mammary and salivary gland neoplasia and ovarian stromal hyperplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

Risk factors for breast cancer in women with proliferative breast disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

Loss of anti-mitotic effects of Bcl-2 with retention of anti-apoptotic activity during tumor progression in a mouse model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

Allelic loss of the PTEN region (10q23) in breast carcinomas of poor pathophenotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

Cooperative interaction between mutant p53 and des(1-3)IGF-I accelerates mammary tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

The biology of erbB-2/neu/HER-2 and its role in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

Detection of amphiregulin and Cripto-1 in mammary tumors from transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

Prognostic factors in early breast carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

The int-2 gene product acts as an epithelial growth factor in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

Progesterone, in Addition to Estrogen, Induces Cyclin D1 Expression in the Murine Mammary Epithelial Cell, in Vivo*

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

Alterations of the c-erbB2 gene in human breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203970

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203970

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Dimensions Publication ID

31 July 2017

1017660498

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Fatcat ID

release_ei7ozlqgtralfh3fmdxme46p64

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Fatcat

https://api.fatcat.wiki/v0/release/ei7ozlqgtralfh3fmdxme46p64

24 November 2022

mapped directly with Wikidata item

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