MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessment. (Q34113855)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851551%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessment (English)

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7 January 2020

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7 January 2020

M C Stubbs

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7 January 2020

Y M Kim

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7 January 2020

A V Krivtsov

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7 January 2020

R D Wright

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7 January 2020

Z Feng

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7 January 2020

J Agarwal

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7 January 2020

S A Armstrong

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7 January 2020

publication date

13 September 2007

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7 January 2020

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7 January 2020

volume

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7 January 2020

issue

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7 January 2020

page(s)

66-77

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Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

7 January 2020

cites work

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Internal tandem duplications of the FLT3 gene are present in leukemia stem cells

5 July 2018

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Dimerization of MLL fusion proteins and FLT3 activation synergize to induce multiple-lineage leukemogenesis

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FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy

5 July 2018

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The role of FLT3 in haematopoietic malignancies

5 July 2018

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5 July 2018

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Two distinct gene expression signatures in pediatric acute lymphoblastic leukemia with MLL rearrangements.

5 July 2018

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5 July 2018

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The roles of FLT3 in hematopoiesis and leukemia

5 July 2018

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Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412.

5 July 2018

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PML/RARalpha and FLT3-ITD induce an APL-like disease in a mouse model

5 July 2018

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FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model

5 July 2018

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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

5 July 2018

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Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

5 July 2018

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Molecular genetics of acute myeloid leukaemia

5 July 2018

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Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

5 July 2018

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A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

5 July 2018

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Mll rearrangements in haematological malignancies: lessons from clinical and biological studies

5 July 2018

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The mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis

5 July 2018

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Oncogenic Transcription Factors in the Human Acute Leukemias

5 July 2018

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Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL

5 July 2018

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

5 July 2018

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An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

5 July 2018

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The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice

5 July 2018

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The transcriptional control of hematopoiesis

5 July 2018

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

5 July 2018

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MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.

5 July 2018

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FLT3 mutations in childhood acute lymphoblastic leukemia

28 October 2018

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FLT3 and MLL intragenic abnormalities in AML reflect a common category of genotoxic stress

28 October 2018

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Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification

28 October 2018

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The critical role of chromosome translocations in human leukemias.

28 October 2018

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Chromosomal translocations in human cancer.

28 October 2018

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Targeted therapies in myeloid leukemias

28 October 2018

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12 December 2020

Molecular rearrangements on chromosome 11q23 predominate in infant acute lymphoblastic leukemia and are associated with specific biologic variables and poor outcome

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12 December 2020

An atlas of chromosomes in hematological malignancies. Example: 11q23 and MLL partners

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12 December 2020

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

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12 December 2020

Identifiers

DOI

10.1038/SJ.LEU.2404951

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851551%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 January 2020

0 references

1 reference

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7 January 2020

PubMed publication ID

17851551

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