Gene silencing, cell fate and nuclear organisation (Q34118361)

31 July 2017

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title

Gene silencing, cell fate and nuclear organisation (English)

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31 July 2017

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Amanda G Fisher

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31 July 2017

author name string

Matthias Merkenschlager

series ordinal

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31 July 2017

publication date

1 April 2002

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Current Opinion in Genetics & Development

31 July 2017

published in

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

193-197

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Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

31 July 2017

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Lineage commitment in lymphopoiesis

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Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis

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Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family

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Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube

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Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification

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7 January 2021

Cracking the transcriptional code for cell specification in the neural tube

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7 January 2021

Drosophila neuroblasts sequentially express transcription factors which specify the temporal identity of their neuronal progeny

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Chromosome territories, nuclear architecture and gene regulation in mammalian cells

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Positions of potential: nuclear organization and gene expression.

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Heterochromatin protein 1 modifies mammalian PEV in a dose- and chromosomal-context-dependent manner

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7 January 2021

A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin.

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7 January 2021

Transcription factor dosage affects changes in higher order chromatin structure associated with activation of a heterochromatic gene

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7 January 2021

Perturbation of nuclear architecture by long-distance chromosome interactions.

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Genetic modification of heterochromatic association and nuclear organization in Drosophila.

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Perinuclear localization of chromatin facilitates transcriptional silencing

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Nuclear pore complexes in the organization of silent telomeric chromatin

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7 January 2021

Common themes in mechanisms of gene silencing

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Specific interactions of chromatin with the nuclear envelope: positional determination within the nucleus in Drosophila melanogaster

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Transcribed genes are localized according to chromosomal position within polarized Drosophila embryonic nuclei

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The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells.

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Re-modelling of nuclear architecture in quiescent and senescent human fibroblasts

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Nuclear relocation of a transactivator subunit precedes target gene activation.

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7 January 2021

Association of Transcriptionally Silent Genes with Ikaros Complexes at Centromeric Heterochromatin

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7 January 2021

Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division

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7 January 2021

Expression of alpha- and beta-globin genes occurs within different nuclear domains in haemopoietic cells.

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7 January 2021

Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes.

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7 January 2021

Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development

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7 January 2021

Dealing from the evolutionary pawnshop: how lymphocytes make decisions

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7 January 2021

Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.

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7 January 2021

The Ikaros gene is required for the development of all lymphoid lineages

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7 January 2021

Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment

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7 January 2021

LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocyte-specific genes

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7 January 2021

Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes

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7 January 2021

Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity

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7 January 2021

Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin

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7 January 2021

Both LyF-1 and an Ets protein interact with a critical promoter element in the murine terminal transferase gene.

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7 January 2021

Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding

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7 January 2021

Down-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activator

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7 January 2021

Binding of Ikaros to the lambda5 promoter silences transcription through a mechanism that does not require heterochromatin formation

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7 January 2021

Chromosome dynamics in the yeast interphase nucleus

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7 January 2021

High mobility of proteins in the mammalian cell nucleus

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7 January 2021

Transcription complex stability and chromatin dynamics in vivo

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7 January 2021

Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator

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7 January 2021

Visualization of gene activity in living cells

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7 January 2021

Translocation of sigma(70) with RNA polymerase during transcription: fluorescence resonance energy transfer assay for movement relative to DNA.

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7 January 2021

10.1016/S0959-437X(02)00286-1

Identifiers

DOI

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31 July 2017

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