Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes. Role of ATP depletion and cytosolic free calcium (Q34109467)

31 July 2017

title

Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes. Role of ATP depletion and cytosolic free calcium (English)

1 reference

31 July 2017

J R Spivey

1 reference

31 July 2017

S F Bronk

series ordinal

1 reference

31 July 2017

G J Gores

series ordinal

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 July 1993

1 reference

Journal of Clinical Investigation

31 July 2017

published in

1 reference

31 July 2017

1 reference

31 July 2017

1 reference

31 July 2017

page(s)

17-24

1 reference

Effects of bile salts on the plasma membranes of isolated rat hepatocytes

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Quantitative aspects of the interaction of bile acids with human serum albumin.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

A new generation of Ca2+ indicators with greatly improved fluorescence properties

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Fructose prevents hypoxic cell death in liver

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Hepatotoxic bile acids increase cytosolic Ca++ activity of isolated rat hepatocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Fluorescence and bioluminescence measurement of cytoplasmic free calcium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

The transport of bile acids in liver cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Release of calcium from the endoplasmic reticulum by bile acids in rat liver cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

The role of calcium in cell injury and repair: a hypothesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Hypoxic liver cell death: critical Po2 and dependence of viability on glycolysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

The liver and intracellular digestion: how liver cells eat!

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Intracellular pH during "chemical hypoxia" in cultured rat hepatocytes. Protection by intracellular acidosis against the onset of cell death

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Ca2+ oscillations induced by hormonal stimulation of individual fura-2-loaded hepatocytes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

The pH dependence of the hemolytic potency of bile salts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Protection by acidotic pH and fructose against lethal injury to rat hepatocytes from mitochondrial inhibitors, ionophores and oxidant chemicals.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Hepatic injury induced by bile salts: correlation between biochemical and morphological events

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Toxic injury from mercuric chloride in rat hepatocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Acidosis protects against lethal oxidative injury of liver sinusoidal endothelial cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Changes in bile acid composition in patients with primary biliary cirrhosis induced by ursodeoxycholic acid administration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Inhibition of proteolysis protects hippocampal neurons from ischemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Activation of mast cells by bile acids

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis. UDCA-PBC Study Group

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

The role of cytosolic Ca2+ in cell injury, necrosis and apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Bile acids influence the growth, oestrogen receptor and oestrogen-regulated proteins of MCF-7 human breast cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Fructose protects rat hepatocytes from anoxic injury. Effect on intracellular ATP, Ca2+i, Mg2+i, Na+i, and pHi

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Effect of ursodeoxycholic acid on the kinetics of the major hydrophobic bile acids in health and in chronic cholestatic liver disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Ruthenium red delays the onset of cell death during oxidative stress of rat hepatocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

A simple and sensitive assay of total serum bile acids

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Isolation of mitochondria from ascites tumor cells permeabilized with digitonin.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Determination of bile acids in needle biopsies of human liver

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Ursodeoxycholate reduces hepatotoxicity of bile salts in primary human hepatocytes

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293519

Induced biosynthesis of liver glucokinase

28 October 2018

1 reference

12 December 2020

Perfusion of the canine colon with unconjugated bile acids. Effect on water and electrolyte transport, morphology, and bile acid absorption

1 reference

12 December 2020

Anionic detergents as divalent cation ionophores across black lipid membranes

1 reference

12 December 2020

[Cytotoxicity of bile acids on cultured cells (author's transl)]

1 reference

12 December 2020

In vitro effect of bile salts on rat liver plasma membrane, lipid fluidity, and ATPase activity

1 reference

12 December 2020

Bleb formation in hepatocytes during drug metabolism is caused by disturbances in thiol and calcium ion homeostasis

1 reference

12 December 2020

Influence of hydroxylation and conjugation of bile salts on their membrane-damaging properties--studies on isolated hepatocytes and lipid membrane vesicles

1 reference

12 December 2020

Effect of chenodeoxycholic and ursodeoxycholic acids on isolated adult human hepatocytes

1 reference

12 December 2020

Calcium ionophore activity of intestinal secretory compounds. An in vitro porcine model for the effects of bile acids, hydroxy-fatty acids and dioctyl sulfosuccinate

1 reference

12 December 2020

Cystamine induces toxicity in hepatocytes through the elevation of cytosolic Ca2+ and the stimulation of a nonlysosomal proteolytic system

1 reference

12 December 2020

Bile salts induce calcium uptake in vitro by human erythrocytes

1 reference

12 December 2020

Response of autophagic protein degradation to physiologic and pathologic stimuli in rat hepatocyte monolayer cultures

1 reference

12 December 2020

Cytosolic-free Ca2+ and cell killing in hepatoma 1c1c7 cells exposed to chemical anoxia

1 reference

12 December 2020

Protein degradation as an index of oxidative stress

1 reference

12 December 2020

Taurine-conjugated bile acids act as calcium ionophores

1 reference

12 December 2020

Reduced activity of the electron transport chain in liver mitochondria isolated from rats with secondary biliary cirrhosis

1 reference

12 December 2020

Structural changes in vesicle membranes and mixed micelles of various lipid compositions after binding of different bile salts

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI116546

1 reference

31 July 2017

1 reference

31 July 2017

1 reference