Canonical non-homologous end joining in mitosis induces genome instability and is suppressed by M-phase-specific phosphorylation of XRCC4 (Q34104535)

31 July 2017

title

Canonical non-homologous end joining in mitosis induces genome instability and is suppressed by M-phase-specific phosphorylation of XRCC4 (English)

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31 July 2017

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Masahiro Terasawa

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31 July 2017

Akira Shinohara

series ordinal

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31 July 2017

Miki Shinohara

series ordinal

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31 July 2017

publication date

28 August 2014

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31 July 2017

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

e1004563

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Creative Commons Attribution 4.0 International

31 July 2017

start time

28 August 2014

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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Mitosis inhibits DNA double-strand break repair to guard against telomere fusions

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The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy

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Playing the end game: DNA double-strand break repair pathway choice

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Cyclin-dependent kinase-dependent phosphorylation of Lif1 and Sae2 controls imprecise nonhomologous end joining accompanied by double-strand break resection

5 July 2018

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DNA damage response is suppressed by the high cyclin-dependent kinase 1 activity in mitotic mammalian cells

5 July 2018

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XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair

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An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway

5 July 2018

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Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.

5 July 2018

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DNA damage signaling in response to double-strand breaks during mitosis

5 July 2018

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5 July 2018

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53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

5 July 2018

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Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis

5 July 2018

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Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.

5 July 2018

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RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

5 July 2018

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The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

5 July 2018

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5 July 2018

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Forkhead-associated domain of yeast Xrs2, a homolog of human Nbs1, promotes nonhomologous end joining through interaction with a ligase IV partner protein, Lif1

5 July 2018

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Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha

5 July 2018

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5 July 2018

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Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

5 July 2018

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RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

5 July 2018

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RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

5 July 2018

1 reference

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Depletion of topoisomerase IIalpha leads to shortening of the metaphase interkinetochore distance and abnormal persistence of PICH-coated anaphase threads.

5 July 2018

1 reference

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DNA repair pathways involved in anaphase bridge formation

5 July 2018

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XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

5 July 2018

1 reference

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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

5 July 2018

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Early G2/M checkpoint failure as a molecular mechanism underlying etoposide-induced chromosomal aberrations.

5 July 2018

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Nonhomologous end joining in yeast

5 July 2018

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Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

5 July 2018

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DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains

5 July 2018

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Inhibition of DNA decatenation, but not DNA damage, arrests cells at metaphase

5 July 2018

1 reference

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Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

In vitro and in vivo interactions of DNA ligase IV with a subunit of the condensin complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Cancer susceptibility and the functions of BRCA1 and BRCA2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Kinetics of core histones in living human cells: little exchange of H3 and H4 and some rapid exchange of H2B.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Basis for avid homologous DNA strand exchange by human Rad51 and RPA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Tid1/Rdh54 promotes colocalization of rad51 and dmc1 during meiotic recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Reinvestigation of the proteolytic activity of neocarzinostatin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Megabase chromatin domains involved in DNA double-strand breaks in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Double-strand break repair in Ku86- and XRCC4-deficient cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Xrcc3 is required for assembly of Rad51 complexes in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

TRF2 Protects Human Telomeres from End-to-End Fusions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Response to ICRF-159 in cell lines resistant to cleavable complex-forming topoisomerase II inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Chromosomal double-strand break repair in Ku80-deficient cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Cell cycle progression and chromosome segregation in mammalian cells cultured in the presence of the topoisomerase II inhibitors ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane; ADR-529] and ICRF-159 (Razoxane).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Localization of RecA-like recombination proteins on chromosomes of the lily at various meiotic stages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Free radical mechanisms in neocarzinostatin-induced DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Mitotic catastrophe: a mechanism for avoiding genomic instability.

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004563

Analysis of anaphase figures in routine histologic sections distinguishes chromosomally unstable from chromosomally stable malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004563

Resolution of anaphase bridges in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004563

Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004563

Neither p21WAF1 nor 14-3-3sigma prevents G2 progression to mitotic catastrophe in human colon carcinoma cells after DNA damage, but p21WAF1 induces stable G1 arrest in resulting tetraploid cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148217

Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25166505

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25166505

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Site-directed mutagenesis facilitated by DpnI selection on hemimethylated DNA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25166505

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1004563

1 reference

31 July 2017

1 reference

31 July 2017

1 reference