Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis (Q34098843)

31 July 2017

title

Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis (English)

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31 July 2017

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Eduardo Mitrani

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31 July 2017

Orit Goldshmidt

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31 July 2017

Eyal Zcharia

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31 July 2017

Rinat Abramovitch

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31 July 2017

Shula Metzger

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31 July 2017

Helena Aingorn

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31 July 2017

Yael Friedmann

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31 July 2017

Volker Schirrmacher

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31 July 2017

Israel Vlodavsky

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31 July 2017

language of work or name

English

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publication date

3 July 2002

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Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

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inferred from page(s)

published in

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

10031-10036

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Molecular properties and involvement of heparanase in cancer progression and mammary gland morphogenesis

31 July 2017

cites work

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Heparanases: endoglycosidases that degrade heparan sulfate proteoglycans

28 July 2018

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Heparanase expression in primary and metastatic pancreatic cancer

28 July 2018

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Expression of heparanase, Mdm2, and erbB2 in ovarian cancer

28 July 2018

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Heparanase: a key enzyme involved in cell invasion

28 July 2018

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Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

28 July 2018

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Heparanase, a potential regulator of cell-matrix interactions

28 July 2018

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Functions of cell surface heparan sulfate proteoglycans

28 July 2018

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Human heparanase. Purification, characterization, cloning, and expression

28 July 2018

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Cloning and functional expression of a human heparanase gene

28 July 2018

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Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis

28 July 2018

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Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis

28 July 2018

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Matrix proteoglycans: from molecular design to cellular function

28 July 2018

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Analysis of subcutaneous angiogenesis by gradient echo magnetic resonance imaging.

28 July 2018

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Major co-localization of the extracellular-matrix degradative enzymes heparanase and gelatinase in tertiary granules of human neutrophils

28 July 2018

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28 July 2018

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Involvement of heparan sulfate and related molecules in sequestration and growth promoting activity of fibroblast growth factor

28 July 2018

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Alterations and role of human cathepsin D in cancer metastasis.

28 July 2018

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Integral membrane heparan sulfate proteoglycans

28 July 2018

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Membrane association of cathepsin B can be induced by transfection of human breast epithelial cells with c-Ha-ras oncogene.

28 July 2018

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Molecular behavior adapts to context: heparanase functions as an extracellular matrix-degrading enzyme or as a T cell adhesion molecule, depending on the local pH.

28 July 2018

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Inhibition of tumor metastasis by heparanase inhibiting species of heparin.

28 July 2018

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Heparanases and tumor metastasis

28 July 2018

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28 July 2018

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Expression of heparanase by platelets and circulating cells of the immune system: possible involvement in diapedesis and extravasation

28 July 2018

1 reference

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Localization of heparanase in normal and pathological human placenta

28 July 2018

1 reference

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Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis

28 October 2018

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Expression pattern and secretion of human and chicken heparanase are determined by their signal peptide sequence

28 October 2018

1 reference

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Expression of heparanase in normal, dysplastic, and neoplastic human colonic mucosa and stroma. Evidence for its role in colonic tumorigenesis

28 October 2018

1 reference

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In vivo prediction of vascular susceptibility to vascular susceptibility endothelial growth factor withdrawal: magnetic resonance imaging of C6 rat glioma in nude mice.

28 October 2018

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Expression of three extracellular matrix degradative enzymes in bladder cancer

28 October 2018

1 reference

12 December 2020

Lymphoma cell-mediated degradation of sulfated proteoglycans in the subendothelial extracellular matrix: relationship to tumor cell metastasis

1 reference

12 December 2020

Inhibition of bladder carcinoma angiogenesis, stromal support, and tumor growth by halofuginone

1 reference

12 December 2020

Inhibition of matrix metalloproteinase-2 expression and bladder carcinoma metastasis by halofuginone

1 reference

12 December 2020

Inhibition of heparanase activity and tumor metastasis by laminarin sulfate and synthetic phosphorothioate oligodeoxynucleotides

1 reference

12 December 2020

Processing of the human heparanase precursor and evidence that the active enzyme is a heterodimer

1 reference

12 December 2020

A mouse hepatocyte carbohydrate-specific receptor and its interaction with liver-metastasizing tumor cells

1 reference

12 December 2020

Evidence that sulphated polysaccharides inhibit tumour metastasis by blocking tumour-cell-derived heparanases

1 reference

12 December 2020

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12 December 2020

Differential effects of the anti-inflammatory compounds heparin, mannose-6-phosphate, and castanospermine on degradation of the vascular basement membrane by leukocytes, endothelial cells, and platelets

1 reference

12 December 2020

Identification of sulfated oligosaccharide-based inhibitors of tumor growth and metastasis using novel in vitro assays for angiogenesis and heparanase activity

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12 December 2020

Heparanase as mediator of angiogenesis: mode of action

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12 December 2020

Identifiers

DOI

10.1073/PNAS.152070599

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31 July 2017

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31 July 2017

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