Analyzing the metabolic stress response of recombinant Escherichia coli cultures expressing human interferon-beta in high cell density fed batch cultures using time course transcriptomic data (Q34088902)

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English	Analyzing the metabolic stress response of recombinant Escherichia coli cultures expressing human interferon-beta in high cell density fed batch cultures using time course transcriptomic data	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

Analyzing the metabolic stress response of recombinant Escherichia coli cultures expressing human interferon-beta in high cell density fed batch cultures using time course transcriptomic data (English)

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Europe PubMed Central

PubMed publication ID

30 July 2017

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Escherichia coli

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author name string

Anuradha B Singh

1

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Europe PubMed Central

PubMed publication ID

30 July 2017

Ashish K Sharma

2

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Europe PubMed Central

PubMed publication ID

30 July 2017

Krishna J Mukherjee

3

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Europe PubMed Central

PubMed publication ID

30 July 2017

publication date

1 December 2011

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Europe PubMed Central

PubMed publication ID

30 July 2017

Molecular BioSystems

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Europe PubMed Central

PubMed publication ID

30 July 2017

8

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Europe PubMed Central

PubMed publication ID

30 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

615-628

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Europe PubMed Central

PubMed publication ID

30 July 2017

Enhanced production of insulin-like growth factor I fusion protein in Escherichia coli by coexpression of the down-regulated genes identified by transcriptome profiling

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Monitoring of transcriptome and proteome profiles to investigate the cellular response of E. coli towards recombinant protein expression under defined chemostat conditions

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21 January 2018

Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli

1 reference

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Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

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Metabolic footprint analysis of recombinant Escherichia coli strains during fed-batch fermentations.

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Systematic phenome analysis of Escherichia coli multiple-knockout mutants reveals hidden reactions in central carbon metabolism.

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A comparative study of global stress gene regulation in response to overexpression of recombinant proteins in Escherichia coli

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Bacterial growth inhibition by overproduction of protein

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Proteomic profiling of recombinant Escherichia coli in high-cell-density fermentations for improved production of an antibody fragment biopharmaceutical

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Integration of gene expression data into genome-scale metabolic models

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Integrating high-throughput and computational data elucidates bacterial networks

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Integrating metabolic, transcriptional regulatory and signal transduction models in Escherichia coli.

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Nutrient-scavenging stress response in an Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system, as explored by gene expression profile analysis

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Near-critical behavior of aminoacyl-tRNA pools in E. coli at rate-limiting supply of amino acids

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Genomic analysis of high-cell-density recombinant Escherichia coli fermentation and "cell conditioning" for improved recombinant protein yield

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Effect of preinduction specific growth rate on secretion of granulocyte macrophage colony stimulating factor by Escherichia coli

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Effect of growth rate on stability and gene expression of recombinant plasmids during continuous and high cell density cultivation of Escherichia coli TG1.

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Optimization of culture on the overproduction of TRAIL in high-cell-density culture by recombinant Escherichia coli

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Optimization of extracellular production of recombinant asparaginase in Escherichia coli in shake-flask and bioreactor

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Amino acid content of recombinant proteins influences the metabolic burden response

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Optimization of Human Granulocyte Macrophage-Colony Stimulating Factor (hGM-CSF) Expression Using Asparaginase and Xylanase Gene’s Signal Sequences in Escherichia coli

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A strategy for high-level expression of soluble and functional human interferon alpha as a GST-fusion protein in E. coli

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The repertoire of DNA-binding transcriptional regulators in Escherichia coli K-12.

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Impact of global transcriptional regulation by ArcA, ArcB, Cra, Crp, Cya, Fnr, and Mlc on glucose catabolism in Escherichia coli

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Therapeutic role of beta-interferons in multiple sclerosis

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Expression and characterization of human interferon-beta1 in the methylotrophic yeast Pichia pastoris

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Overexpression of a synthetic gene encoding human alpha interferon in Escherichia coli.

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Growth rate-dependent global effects on gene expression in bacteria

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Recombinant protein expression in high cell density fed-batch cultures of Escherichia coli

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Growth-rate-dependent partitioning of RNA polymerases in bacteria

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Systems biology approach reveals that overflow metabolism of acetate in Escherichia coli is triggered by carbon catabolite repression of acetyl-CoA synthetase

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Limiting factors in Escherichia coli fed-batch production of recombinant proteins.

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Overexpression and purification of recombinant human interferon alpha2b in Escherichia coli

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RegulonDB (version 3.2): transcriptional regulation and operon organization in Escherichia coli K-12

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Dissecting the logical types of network control in gene expression profiles

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The Pathway Tools software

1 reference

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The comprehensive updated regulatory network of Escherichia coli K-12.

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The small heat-shock proteins IbpA and IbpB reduce the stress load of recombinant Escherichia coli and delay degradation of inclusion bodies

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Recombinant protein folding and misfolding in Escherichia coli

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Leucine-responsive regulatory protein: a global regulator of gene expression in E. coli

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Differential regulation of Escherichia coli topoisomerase I by Fis.

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Effects of Fis on Escherichia coli gene expression during different growth stages.

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The HU regulon is composed of genes responding to anaerobiosis, acid stress, high osmolarity and SOS induction

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Host factor Hfq of Escherichia coli stimulates elongation of poly(A) tails by poly(A) polymerase I.

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High-level translation initiation

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RpoS regulation of gene expression during exponential growth of Escherichia coli K12.

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Identifiers

10.1039/C1MB05414G

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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