Regulation and function of the cyclic nucleotide phosphodiesterase (PDE3) gene family (Q34070572)

30 July 2017

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title

Regulation and function of the cyclic nucleotide phosphodiesterase (PDE3) gene family (English)

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30 July 2017

Shakur Y

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30 July 2017

Holst LS

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30 July 2017

Landstrom TR

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30 July 2017

Movsesian M

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30 July 2017

Degerman E

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30 July 2017

Manganiello V

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30 July 2017

publication date

1 January 2001

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Progress in Molecular Biology and Translational Science

30 July 2017

published in

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30 July 2017

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30 July 2017

page(s)

241-277

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Structure, localization, and regulation of cGMP-inhibited phosphodiesterase (PDE3)

30 July 2017

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An effect of insulin on adipose-tissue adenosine 3':5'-cyclic monophosphate phosphodiesterase

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Purification and characterization of a human platelet cyclic nucleotide phosphodiesterase

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Precision substrate targeting of protein kinases. The cGMP- and cAMP-dependent protein kinases

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Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A)

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Identification of the site in the cGMP-inhibited phosphodiesterase phosphorylated in adipocytes in response to insulin and isoproterenol

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7 January 2021

Cyclic nucleotide phosphodiesterase 3B is a downstream target of protein kinase B and may be involved in regulation of effects of protein kinase B on thymidine incorporation in FDCP2 cells

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7 January 2021

Selective inhibition of two soluble adenosine cyclic 3',5'-phosphate phosphodiesterases partially purified from calf liver

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7 January 2021

Nitric oxide regulates the calcium current in isolated human atrial myocytes.

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7 January 2021

Cardiac type cGMP-inhibited phosphodiesterase (PDE3A) gene structure: similarity and difference to adipocyte type PDE3B gene.

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7 January 2021

Characterization of the cDNA and gene encoding human PDE3B, the cGIP1 isoform of the human cyclic GMP-inhibited cyclic nucleotide phosphodiesterase family

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7 January 2021

Molecular cloning and chromosomal assignment of the human homologue of the rat cGMP-inhibited phosphodiesterase 1 (PDE3A)--a gene involved in fat metabolism located at 11p 15.1

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7 January 2021

Distinctive anatomical patterns of gene expression for cGMP-inhibited cyclic nucleotide phosphodiesterases

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7 January 2021

Cyclic nucleotide PDE-3. Quantitation of PDE-3A and -3B mRNAs in rat tissues by RNase protection assay

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7 January 2021

Expression of cyclic GMP-inhibited phosphodiesterases 3A and 3B (PDE3A and PDE3B) in rat tissues: differential subcellular localization and regulated expression by cyclic AMP

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7 January 2021

Differential cellular pattern of gene expression for two distinct cGMP-inhibited cyclic nucleotide phosphodiesterases in developing and mature rat brain

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7 January 2021

Single-step affinity purification, partial structure and properties of human platelet cGMP inhibited cAMP phosphodiesterase

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7 January 2021

Therapeutic potential of selective PDE inhibitors in asthma

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7 January 2021

Down-regulation of cyclic-nucleotide phosphodiesterase 3B in 3T3-L1 adipocytes induced by tumour necrosis factor alpha and cAMP

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7 January 2021

Characterization of two recombinant PDE3 (cGMP-inhibited cyclic nucleotide phosphodiesterase) isoforms, RcGIP1 and HcGIP2, expressed in NIH 3006 murine fibroblasts and Sf9 insect cells

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7 January 2021

Expression and characterization of deletion recombinants of two cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE-3).

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7 January 2021

Expression and mutagenesis of the catalytic domain of cGMP-inhibited phosphodiesterase (PDE3) cloned from human platelets

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7 January 2021

Divalent metal cation requirement and possible classification of cGMP-inhibited phosphodiesterase as a metallohydrolase

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7 January 2021

Evidence for the presence of essential histidine and cysteine residues in platelet cGMP-inhibited phosphodiesterase

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7 January 2021

Partial characterization of the active site human platelet cAMP phosphodiesterase, PDE3A, by site-directed mutagenesis

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7 January 2021

Selective inhibitors of specific phosphodiesterases in intact adipocytes

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7 January 2021

Purification and properties of the cGMP-inhibited cAMP phosphodiesterase from bovine aortic smooth muscle

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7 January 2021

Characterization of membrane-bound cyclic nucleotide phosphodiesterases from bovine aortic smooth muscle

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7 January 2021

Cytosolic and sarcoplasmic reticulum-associated low Km, cGMP-inhibited cAMP phosphodiesterase in mammalian myocardium

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7 January 2021

Multiple transcripts for the human cardiac form of the cGMP-inhibited cAMP phosphodiesterase

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7 January 2021

Functions of the N-terminal region of cyclic nucleotide phosphodiesterase 3 (PDE 3) isoforms

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7 January 2021

Insulin and lipolytic hormones stimulate the same phosphodiesterase isoform in rat adipose tissue

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7 January 2021

Various phosphodiesterase subtypes mediate the in vivo antilipolytic effect of insulin on adipose tissue and skeletal muscle in man.

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7 January 2021

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

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7 January 2021

Mitogen-activated protein kinase and p70 ribosomal protein S6 kinase are not involved in the insulin-dependent stimulation of cAMP phosphodiesterase kinase in rat adipocytes

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7 January 2021

Phosphorylation and activation of phosphodiesterase type 3B (PDE3B) in adipocytes in response to serine/threonine phosphatase inhibitors: deactivation of PDE3B in vitro by protein phosphatase type 2A.

1 reference

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7 January 2021

Essential role of phosphatidylinositol 3-kinase in insulin-induced activation and phosphorylation of the cGMP-inhibited cAMP phosphodiesterase in rat adipocytes. Studies using the selective inhibitor wortmannin

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7 January 2021

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

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7 January 2021

Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families

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7 January 2021

Molecular cloning of a second form of rac protein kinase

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7 January 2021

A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans

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7 January 2021

Genetic analysis of protein kinase B (AKT) in Drosophila

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7 January 2021

A role for protein kinase Bbeta/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes

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7 January 2021

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

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7 January 2021

Akt signaling: linking membrane events to life and death decisions

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7 January 2021

Mechanism of activation and function of protein kinase B.

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7 January 2021

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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7 January 2021

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

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7 January 2021

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

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7 January 2021

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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7 January 2021

Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades

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7 January 2021

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7 January 2021

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

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7 January 2021

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

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7 January 2021

Regulation of protein kinase B in rat adipocytes by insulin, vanadate, and peroxovanadate. Membrane translocation in response to peroxovanadate

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7 January 2021

Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms

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7 January 2021

Insulin-induced translocation of protein kinase B to the plasma membrane in rat adipocytes

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7 January 2021

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7 January 2021

Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt

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7 January 2021

Protein kinase B/Akt induces resumption of meiosis in Xenopus oocytes.

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7 January 2021

Serine/threonine protein phosphatases

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7 January 2021

Regulation of protein kinase cascades by protein phosphatase 2A.

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7 January 2021

Molecular mechanisms of the protein serine/threonine phosphatases

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7 January 2021

Novel protein serine/threonine phosphatases: Variety is the spice of life

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7 January 2021

Molecular cloning, expression, and characterization of a novel human serine/threonine protein phosphatase, PP7, that is homologous to Drosophila retinal degeneration C gene product (rdgC)

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7 January 2021

Direct effect of insulin and insulin-like growth factor-I on the secretory activity of rat pancreatic beta cells

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7 January 2021

The Adenylate cyclase-cyclic AMP system in islets of langerhans and its role in the control of insulin release

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7 January 2021

Mechanism of glucose-induced insulin secretion

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7 January 2021

The calcium/calmodulin-dependent phosphodiesterase PDE1C down-regulates glucose-induced insulin secretion

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7 January 2021

Purification of an insulin-sensitive cyclic AMP phosphodiesterase from rat liver

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7 January 2021

The insulin- and glucagon-stimulated 'dense-vesicle' high-affinity cyclic AMP phosphodiesterase from rat liver. Purification, characterization and inhibitor sensitivity

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7 January 2021

Acute in vivo stimulation of low-Km cyclic AMP phosphodiesterase activity by insulin in rat-liver Golgi fractions

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7 January 2021

Cell-free stimulation of the insulin-sensitive cAMP phosphodiesterase by the joint actions of ATP and the soluble fraction from insulin-treated rat liver

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7 January 2021

Specific inhibition of the cGMP-inhibited cAMP phosphodiesterase blocks the insulin-like antilipolytic effect of growth hormone in rat adipocytes

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7 January 2021

Insulin induced phosphorylation and activation of the cGMP-inhibited cAMP phosphodiesterase in human platelets

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7 January 2021

Stimulation by Insulin of a Serine Kinase in Human Platelets That Phosphorylates and Activates the cGMP-Inhibited cAMP Phosphodiesterase

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7 January 2021

Phosphodiesterase activity in human subcutaneous adipose tissue in insulin- and noninsulin-dependent diabetes mellitus

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7 January 2021

Spontaneous diabetic BB rat: studies of cyclic adenosine 3',5'-monophosphate phosphodiesterase and calmodulin

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7 January 2021

Cyclic nucleotide phosphodiesterase 3 expression in vivo: evidence for tissue-specific expression of phosphodiesterase 3A or 3B mRNA and activity in the aorta and adipose tissue of atherosclerosis-prone insulin-resistant rats

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7 January 2021

Improvement in insulin resistance and the restoration of reduced phosphodiesterase 3B gene expression by pioglitazone in adipose tissue of obese diabetic KKAy mice.

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7 January 2021

Thyroid Hormone Modulation of Epinephrine-Induced Lipolysis in Rat Adipocytes: A Possible Role of Calcium*

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7 January 2021

Effects of thyroid hormone on regulation of lipolysis and adenosine 3',5'-monophosphate metabolism in 3T3-L1 adipocytes

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7 January 2021

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

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7 January 2021

Induction of phosphodiesterases 3B, 4A4, 4D1, 4D2, and 4D3 in Jurkat T-cells and in human peripheral blood T-lymphocytes by 8-bromo-cAMP and Gs-coupled receptor agonists. Potential role in beta2-adrenoreceptor desensitization

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7 January 2021

Subclasses of cyclic AMP-specific phosphodiesterase in left ventricular muscle and their involvement in regulating myocardial contractility

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7 January 2021

Comparison of cyclic nucleotide phosphodiesterase isoenzymes in rat and rabbit ventricular myocardium: positive inotropic and phosphodiesterase inhibitory effects of Org 30029, milrinone and rolipram

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7 January 2021

Post-receptor modulation of the effects of cyclic AMP in isolated cardiac myocytes

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7 January 2021

Species-dependent differences in the properties of particulate cyclic nucleotide phosphodiesterase from rat and rabbit ventricular myocardium

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7 January 2021

Cyclic nucleotide phosphodiesterases and vascular smooth muscle

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7 January 2021

Role of phosphodiesterase isoenzymes in regulating intracellular cyclic AMP in adenosine-stimulated smooth muscle cells

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7 January 2021

Comparison of the effects of cilostazol and milrinone on intracellular cAMP levels and cellular function in platelets and cardiac cells

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7 January 2021

Altered expression of cyclic nucleotide phosphodiesterase isozymes during culture of aortic endothelial cells

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7 January 2021

Expression of phenotype- and proliferation-related genes in rat aortic smooth muscle cells in primary culture

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7 January 2021

An investigation into the alpha-adrenoceptor mediating renal nerve-induced calcium reabsorption by the rat kidney

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7 January 2021

Endothelium-dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors

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https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Effects of Nitrovasodilators on Platelet Cyclic Nucleotide Levels in Rabbit Blood; Role for Cyclic AMP in Synergistic Inhibition of Platelet Function by SIN-1 and Prostaglandin E1

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7 January 2021

Effects of SK&F 94120, an inhibitor of cyclic nucleotide phosphodiesterase type III, on human platelets

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7 January 2021

Two isoforms of cGMP-inhibited cyclic nucleotide phosphodiesterases in human tissues distinguished by their responses to vesnarinone, a new cardiotonic agent

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7 January 2021

Effect of Cilostazol, a Cyclic AMP Phosphodiesterase Inhibitor, on the Proliferation of Rat Aortic Smooth Muscle Cells in Culture

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7 January 2021

Milrinone, a phosphodiesterase inhibitor, suppresses intimal thickening after photochemically induced endothelial injury in the mouse femoral artery

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7 January 2021

Effect of cilostazol in preventing restenosis after percutaneous transluminal coronary angioplasty

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7 January 2021

Effects of probucol and cilostazol alone and in combination on frequency of poststenting restenosis

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7 January 2021

Impact of cilostazol on intimal proliferation after directional coronary atherectomy

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7 January 2021

The Effect of Cilostazol, a Cyclic Nucleotide Phosphodiesterase III Inhibitor, on Heparin-Binding EGF-like Growth Factor Expression in Macrophages and Vascular Smooth Muscle Cells

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https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Cyclic nucleotides and phosphodiesterases and airway function

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Identification and function of cyclic nucleotide phosphodiesterase isoenzymes in airway epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Trials of the bronchodilator activity of the isoenzyme-selective phosphodiesterase inhibitor AH 21-132 in healthy volunteers during a methacholine challenge test

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Bronchoprotective effect of an intrabronchial administration of cilostazol powder and a nebulized PDE1 and PDE4 inhibitor KF19514 in guinea pigs.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Intratracheal administration of phosphodiesterase III inhibitor attenuates bronchoconstriction in cats: a preliminary report.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Bronchodilator effect of inhaled olprinone, a phosphodiesterase 3 inhibitor, in asthmatic patients

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Effects of isoenzyme selective phosphodiesterase inhibitors on bacterial lipopolysaccharide-induced bronchial hyperreactivity in guinea pigs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

The effect of vesnarinone on TNF alpha production in human peripheral blood mononuclear cells and microglia: a preclinical study for the treatment of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

cAMP concentrations, cAMP dependent protein kinase activity, and phospholamban in non-failing and failing myocardium

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Increase of the 40,000-mol wt pertussis toxin substrate (G protein) in the failing human heart

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Increase of Gi alpha in human hearts with dilated but not ischemic cardiomyopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Evaluation of a new bipyridine inotropic agent--milrinone--in patients with severe congestive heart failure

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Long-term therapy with a new cardiotonic agent, WIN 47203: drug-dependent improvement in cardiac performance and progression of the underlying disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

The acute hemodynamic effects of a new agent, MDL 17,043, in the treatment of congestive heart failure

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Oral amrinone for the treatment of chronic congestive heart failure: results of a multicenter randomized double-blind and placebo-controlled withdrawal study

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Positive inotropic and vasodilator actions of milrinone in patients with severe congestive heart failure. Dose-response relationships and comparison to nitroprusside

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Long-term oral administration of amrinone for congestive heart failure: lack of efficacy in a multicenter controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

A comparison of oral milrinone, digoxin, and their combination in the treatment of patients with chronic heart failure

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Multicenter trial of oral enoximone in patients with moderate to moderately severe congestive heart failure. Lack of benefit compared with placebo. Enoximone Multicenter Trial Group

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Evaluation of the effect of phosphodiesterase inhibitors on mortality in chronic heart failure patients. A meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

The development of positive inotropic agents for chronic heart failure: how have we gone astray?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Beta-adrenergic receptor agonists and cyclic nucleotide phosphodiesterase inhibitors: shifting the focus from inotropy to cyclic adenosine monophosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Effect of the novel antiplatelet agent cilostazol on plasma lipoproteins in patients with intermittent claudication

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Reduction in pulmonary hypertension and in airway resistances by enoximone (MDL 17,043) in decompensated COPD.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

Bronchodilator and bronchoprotective effects of cilostazol in humans in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2800%2966031-2

7 January 2021

10.1016/S0079-6603(00)66031-2

Identifiers

DOI

1 reference

30 July 2017

1 reference