Serotonergic 5-HT(2B) receptor controls tissue-nonspecific alkaline phosphatase activity in osteoblasts via eicosanoids and phosphatidylinositol-specific phospholipase C (Q34074295)

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English	Serotonergic 5-HT(2B) receptor controls tissue-nonspecific alkaline phosphatase activity in osteoblasts via eicosanoids and phosphatidylinositol-specific phospholipase C	scientific article

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6 February 2020

Serotonergic 5-HT(2B) receptor controls tissue-nonspecific alkaline phosphatase activity in osteoblasts via eicosanoids and phosphatidylinositol-specific phospholipase C (English)

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6 February 2020

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Sophie Mouillet-Richard

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6 February 2020

Jean-Marie Launay

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Jean-Marie Launay

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6 February 2020

Odile Kellermann

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Odile Kellermann

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6 February 2020

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Anne Baudry

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6 February 2020

Juliette Bitard

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6 February 2020

Morgane Locker

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6 February 2020

Anne Poliard

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23 June 2010

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6 February 2020

Journal of Biological Chemistry

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6 February 2020

285

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6 February 2020

34

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6 February 2020

26066-26073

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6 February 2020

The emerging role of serotonin (5-hydroxytryptamine) in the skeleton and its mediation of the skeletal effects of low-density lipoprotein receptor-related protein 5 (LRP5).

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EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures

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The effect of collagen I mimetic peptides on mesenchymal stem cell adhesion and differentiation, and on bone formation at hydroxyapatite surfaces

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5 July 2018

Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum

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Signaling at G-protein-coupled serotonin receptors: recent advances and future research directions

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5 July 2018

What do we know about serotonin?

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Skeletal effects of serotonin (5-hydroxytryptamine) transporter inhibition: evidence from clinical studies.

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The roles of prostanoids, leukotrienes, and platelet-activating factor in bone metabolism and disease

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The serotonin 5-HT2B receptor controls bone mass via osteoblast recruitment and proliferation

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Stepwise control of osteogenic differentiation by 5-HT(2B) receptor signaling: nitric oxide production and phospholipase A2 activation.

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Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone

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Modulation of serotonergic receptor signaling and cross-talk by prion protein.

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Non-prostaglandin eicosanoids in fever and anapyrexia

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5 July 2018

5-HT2 receptors.

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5 July 2018

Specification of catecholaminergic and serotonergic neurons.

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5 July 2018

Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization

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5 July 2018

Expression of serotonin receptors in bone

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5 July 2018

PDZ-dependent activation of nitric-oxide synthases by the serotonin 2B receptor

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COX-2 inhibitors. A new class of antiangiogenic agents

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5 July 2018

Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia

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5 July 2018

Lineage-dependent collagen expression and assembly during osteogenic or chondrogenic differentiation of a mesoblastic cell line

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5 July 2018

Novel discriminatory ligands for 5-HT2B receptors.

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5 July 2018

Hypophosphatasia and the role of alkaline phosphatase in skeletal mineralization

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5-HT2 receptor subtypes: a family re-united?

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Tissue non-specific alkaline phosphatase is expressed in both embryonic and extraembryonic lineages during mouse embryogenesis but is not required for migration of primordial germ cells.

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Controlled conversion of an immortalized mesodermal progenitor cell towards osteogenic, chondrogenic, or adipogenic pathways

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Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils

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Missense mutations of the tissue-nonspecific alkaline phosphatase gene in hypophosphatasia

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5 July 2018

Alkaline phosphatase. I. Kinetics and inhibition by levamisole of purified isoenzymes from humans

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Neurotransmitter action in osteoblasts: expression of a functional system for serotonin receptor activation and reuptake

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Inhibition of the serotonin (5-hydroxytryptamine) transporter reduces bone accrual during growth

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Serotonin (5-hydroxytryptamine) transporter inhibition causes bone loss in adult mice independently of estrogen deficiency

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21 January 2018

Site-specific localization of two distinct phosphatases along the osteoblast plasma membrane: tissue non-specific alkaline phosphatase and plasma membrane calcium ATPase.

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21 January 2018

Orientation of mineral crystallites and mineral density during skeletal development in mice deficient in tissue nonspecific alkaline phosphatase

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Inactivation of two mouse alkaline phosphatase genes and establishment of a model of infantile hypophosphatasia.

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12 December 2020

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Pharmacological characterization of in vivo properties of putative mixed 5-HT1A agonist/5-HT(2A/2C) antagonist anxiolytics. II. Drug discrimination and behavioral observation studies in rats

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Contribution of matrix vesicles and alkaline phosphatase to ectopic bone formation

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https://pubmed.ncbi.nlm.nih.gov/20573958

12 December 2020

based on heuristic

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10.1074/JBC.M109.073791

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6 February 2020

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6 February 2020

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