Loqs and R2D2 act sequentially in the siRNA pathway in Drosophila (Q34056595)

30 July 2017

title

Loqs and R2D2 act sequentially in the siRNA pathway in Drosophila (English)

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30 July 2017

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GOA release 2020-03-11

small interfering RNA

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Pei-Hsuan Wu

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João Trindade Marques

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https://orcid.org/0000-0002-3457-3320

author name string

Kevin Kim

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30 July 2017

Trevis M Alleyne

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30 July 2017

Nadereh Jafari

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30 July 2017

Richard W Carthew

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30 July 2017

publication date

27 December 2009

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Nature Structural & Molecular Biology

30 July 2017

published in

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

24-30

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Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform

30 July 2017

cites work

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5 July 2018

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Small RNAs as guardians of the genome

5 July 2018

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Origins and Mechanisms of miRNAs and siRNAs

5 July 2018

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Small silencing RNAs: an expanding universe

5 July 2018

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Comparative analysis of argonaute-dependent small RNA pathways in Drosophila

5 July 2018

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5 July 2018

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Endogenous RNA interference provides a somatic defense against Drosophila transposons

5 July 2018

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Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster

5 July 2018

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Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells

5 July 2018

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An endogenous small interfering RNA pathway in Drosophila

5 July 2018

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The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs

5 July 2018

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Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

5 July 2018

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Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

5 July 2018

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Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells

5 July 2018

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Dicer-1, but not Loquacious, is critical for assembly of miRNA-induced silencing complexes

5 July 2018

1 reference

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Construction of small RNA cDNA libraries for deep sequencing

5 July 2018

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Sorting of Drosophila small silencing RNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

Carbodiimide-mediated cross-linking of RNA to nylon membranes improves the detection of siRNA, miRNA and piRNA by northern blot

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

Distinct populations of primary and secondary effectors during RNAi in C. elegans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

A genomewide screen for components of the RNAi pathway in Drosophila cultured cells

5 July 2018

1 reference

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The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

RNA interference directs innate immunity against viruses in adult Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

Methylation protects miRNAs and siRNAs from a 3'-end uridylation activity in Arabidopsis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

A protein sensor for siRNA asymmetry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

MicroRNAs and other tiny endogenous RNAs in C. elegans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

Ribonuclease activity and RNA binding of recombinant human Dicer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

The Drosophila gene collection: identification of putative full-length cDNAs for 70% of D. melanogaster genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

RNAi is activated during Drosophila oocyte maturation in a manner dependent on aubergine and spindle-E.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

Targeted mRNA degradation by double-stranded RNA in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919300

A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

5 July 2018

1 reference

The regulatory activity of microRNA* species has substantial influence on microRNA and 3' UTR evolution

21 January 2018

1 reference

The miRNA pathway intrinsically controls self-renewal of Drosophila germline stem cells

21 January 2018

1 reference

Molecular requirements for RNA-induced silencing complex assembly in the Drosophila RNA interference pathway.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/NSMB.1735

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30 July 2017

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30 July 2017

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