The neurovirulence and neuroinvasiveness of chimeric tick-borne encephalitis/dengue virus can be attenuated by introducing defined mutations into the envelope and NS5 protein genes and the 3' non-coding region of the genome (Q34036778)

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English	The neurovirulence and neuroinvasiveness of chimeric tick-borne encephalitis/dengue virus can be attenuated by introducing defined mutations into the envelope and NS5 protein genes and the 3' non-coding region of the genome	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

The neurovirulence and neuroinvasiveness of chimeric tick-borne encephalitis/dengue virus can be attenuated by introducing defined mutations into the envelope and NS5 protein genes and the 3' non-coding region of the genome (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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Brian R. Murphy

6

object named as

Brian R Murphy

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Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

Amber R Engel

1

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Europe PubMed Central

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30 July 2017

Alexander A Rumyantsev

2

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Europe PubMed Central

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30 July 2017

Olga A Maximova

3

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Europe PubMed Central

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30 July 2017

James M Speicher

4

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Europe PubMed Central

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30 July 2017

Brian Heiss

5

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Europe PubMed Central

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30 July 2017

Alexander G Pletnev

7

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30 July 2017

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publication date

1 July 2010

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Europe PubMed Central

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30 July 2017

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Europe PubMed Central

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30 July 2017

405

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Europe PubMed Central

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30 July 2017

1

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Europe PubMed Central

PubMed publication ID

30 July 2017

243-252

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Europe PubMed Central

PubMed publication ID

30 July 2017

Dengue virus NS5 inhibits interferon-alpha signaling by blocking signal transducer and activator of transcription 2 phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914112

5 July 2018

Mechanisms of evasion of the type I interferon antiviral response by flaviviruses

1 reference

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5 July 2018

NS5 of dengue virus mediates STAT2 binding and degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914112

5 July 2018

Tick-borne flaviviruses: dissecting host immune responses and virus countermeasures

1 reference

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Evaluation of St. Louis encephalitis virus/dengue virus type 4 antigenic chimeric viruses in mice and rhesus monkeys

1 reference

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Comparative Neuropathogenesis and Neurovirulence of Attenuated Flaviviruses in Nonhuman Primates

1 reference

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Tick-borne encephalitis incidence in Central and Eastern Europe: consequences of political transition

1 reference

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Evaluation of the Langat/dengue 4 chimeric virus as a live attenuated tick-borne encephalitis vaccine for safety and immunogenicity in healthy adult volunteers

1 reference

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Identification of Residues Critical for the Interferon Antagonist Function of Langat Virus NS5 Reveals a Role for the RNA-Dependent RNA Polymerase Domain

1 reference

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rDEN2/4Delta30(ME), a live attenuated chimeric dengue serotype 2 vaccine is safe and highly immunogenic in healthy dengue-naïve adults.

1 reference

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The live attenuated dengue serotype 1 vaccine rDEN1Delta30 is safe and highly immunogenic in healthy adult volunteers.

1 reference

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Chimeric West Nile/dengue virus vaccine candidate: preclinical evaluation in mice, geese and monkeys for safety and immunogenicity.

1 reference

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A tick-borne Langat virus mutant that is temperature sensitive and host range restricted in neuroblastoma cells and lacks neuroinvasiveness for immunodeficient mice

1 reference

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1 reference

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Comparison of live and inactivated tick-borne encephalitis virus vaccines for safety, immunogenicity and efficacy in rhesus monkeys

1 reference

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5 July 2018

Steps of the tick-borne encephalitis virus replication cycle that affect neuropathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914112

5 July 2018

Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914112

5 July 2018

Molecular determinants of virulence: the structural and functional basis for flavivirus attenuation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914112

5 July 2018

Mutations which enhance the replication of dengue virus type 4 and an antigenic chimeric dengue virus type 2/4 vaccine candidate in Vero cells

1 reference

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Epidemiology and ecology of TBE relevant to the production of effective vaccines

1 reference

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5 July 2018

A Live, Attenuated Dengue Virus Type 1 Vaccine Candidate with a 30-Nucleotide Deletion in the 3' Untranslated Region Is Highly Attenuated and Immunogenic in Monkeys

1 reference

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Genetic basis of attenuation of dengue virus type 4 small plaque mutants with restricted replication in suckling mice and in SCID mice transplanted with human liver cells

1 reference

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Paired charge-to-alanine mutagenesis of dengue virus type 4 NS5 generates mutants with temperature-sensitive, host range, and mouse attenuation phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914112

5 July 2018

Attenuation and immunogenicity in humans of a live dengue virus type-4 vaccine candidate with a 30 nucleotide deletion in its 3'-untranslated region.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914112

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Chemical mutagenesis of dengue virus type 4 yields mutant viruses which are temperature sensitive in vero cells or human liver cells and attenuated in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914112

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Attenuation of the Langat tick-borne flavivirus by chimerization with mosquito-borne flavivirus dengue type 4

1 reference

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1 reference

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1 reference

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1 reference

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TBE infection in an incomplete immunized person at-risk who lives in a high-endemic area--impact on current recommendations for immunization of high-risk groups

1 reference

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Tick-borne encephalitis--a European health challenge. Conference report of the 8th meeting of the International Scientific Working Group on Tick-borne Encephalitis (ISW TBE).

1 reference

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Autonomic involvement in tick-borne encephalitis (TBE): report of five cases.

1 reference

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Two severe cases of tick-borne encephalitis despite complete active vaccination--the significance of neutralizing antibodies

1 reference

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Vaccine failures after active immunisation against tick-borne encephalitis

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A fatal tick bite occurring during the course of tick-borne encephalitis vaccination

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2010.06.014

7 January 2021

Tick-borne encephalitis

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2010.06.014

7 January 2021

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10.1016/J.VIROL.2010.06.014

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Europe PubMed Central

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30 July 2017

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Europe PubMed Central

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30 July 2017

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