Nicotinic partial agonists varenicline and sazetidine-A have differential effects on affective behavior. (Q34035211)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20435920%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Nicotinic partial agonists varenicline and sazetidine-A have differential effects on affective behavior (English)

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1 February 2020

1 reference

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1 February 2020

Laura M Castellano

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20435920%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Julie A Blendy

series ordinal

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1 February 2020

language of work or name

English

0 references

publication date

30 April 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20435920%20AND%20SRC:MED&resulttype=core&format=json

Journal of Pharmacology and Experimental Therapeutics

1 February 2020

published in

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1 February 2020

volume

334

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1 February 2020

issue

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1 February 2020

page(s)

665-672

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Varenicline: a first-line treatment option for smoking cessation

1 February 2020

cites work

1 reference

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Varenicline augmentation in depressed smokers: an 8-week, open-label study

5 July 2018

1 reference

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Anxiolytic effects of nicotine in a rodent test of approach-avoidance conflict

5 July 2018

1 reference

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Rodent models of nicotine withdrawal syndrome

5 July 2018

1 reference

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Cytisine-based nicotinic partial agonists as novel antidepressant compounds

5 July 2018

1 reference

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Varenicline improves mood and cognition during smoking abstinence

5 July 2018

1 reference

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Analgesic effects of Sazetidine-A, a new nicotinic cholinergic drug

5 July 2018

1 reference

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Affective and somatic aspects of spontaneous and precipitated nicotine withdrawal in C57BL/6J and BALB/cByJ mice

5 July 2018

1 reference

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Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptors

5 July 2018

1 reference

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Voluntary oral nicotine intake in mice down-regulates GluR2 but does not modulate depression-like behaviors

5 July 2018

1 reference

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It is not "either/or": activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood

5 July 2018

1 reference

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Cytisine, a partial agonist of high-affinity nicotinic acetylcholine receptors, has antidepressant-like properties in male C57BL/6J mice

5 July 2018

1 reference

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Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

The nicotinic antagonist mecamylamine has antidepressant-like effects in wild-type but not beta2- or alpha7-nicotinic acetylcholine receptor subunit knockout mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Guidelines on nicotine dose selection for in vivo research.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Sazetidine-A, a novel ligand that desensitizes alpha4beta2 nicotinic acetylcholine receptors without activating them

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Reflections on smoking relapse research

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Anxiolytic-like activity of oxytocin in male mice: behavioral and autonomic evidence, therapeutic implications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Recent advances in animal models of chronic antidepressant effects: the novelty-induced hypophagia test

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

5 July 2018

Smoking and depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Effect of nicotine and nicotinic receptors on anxiety and depression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Antagonism of nicotinic acetylcholine receptors by inhibitors of monoamine uptake.

5 July 2018

1 reference

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Antidepressants noncompetitively inhibit nicotinic acetylcholine receptor function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Neurobiological similarities in depression and drug dependence: a self-medication hypothesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Nicotinic acetylcholine receptor antagonist effect of fluoxetine in rat hippocampal slices

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Acute effects of nicotine on prolactin release in the rat: agonist and antagonist effects of a single injection of nicotine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Sazetidine-A, a selective alpha4beta2 nicotinic receptor desensitizing agent and partial agonist, reduces nicotine self-administration in rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition

29 October 2018

1 reference

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Varenicline has antidepressant-like activity in the forced swim test and augments sertraline's effect

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Varenicline versus bupropion SR or placebo for smoking cessation: a pooled analysis

29 October 2018

1 reference

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Elevated zero maze: a paradigm to evaluate antianxiety effects of drugs

29 October 2018

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cAMP response element-binding protein deficiency allows for increased neurogenesis and a rapid onset of antidepressant response.

29 October 2018

1 reference

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Anxiolytic effect of serotonin depletion in the novelty-induced hypophagia test

29 October 2018

1 reference

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A combined marble burying-locomotor activity test in mice: a practical screening test with sensitivity to different classes of anxiolytics and antidepressants

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Pharmacogenomic evaluation of the antidepressant citalopram in the mouse tail suspension test.

29 October 2018

1 reference

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Differential behavioral effects of the antidepressants reboxetine, fluoxetine, and moclobemide in a modified forced swim test following chronic treatment

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

High-affinity nicotinic acetylcholine receptors are required for antidepressant effects of amitriptyline on behavior and hippocampal cell proliferation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Validation of a simple, ethologically relevant paradigm for assessing anxiety in mice

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913767

Antidepressant-like effects of the subtype-selective nicotinic acetylcholine receptor agonist, SIB-1508Y, in the learned helplessness rat model of depression

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20435920

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1124/JPET.110.166280

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20435920%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20435920%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

20435920

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20435920%20AND%20SRC:MED&resulttype=core&format=json