Differences in the large extracellular loop between the K(+)-Cl(-) cotransporters KCC2 and KCC4. (Q34025354)

30 July 2017

title

Differences in the large extracellular loop between the K(+)-Cl(-) cotransporters KCC2 and KCC4. (English)

1 reference

30 July 2017

Eckhard Friauf

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Anna-Maria Hartmann

1 reference

30 July 2017

Meike Wenz

1 reference

30 July 2017

Adriana Mercado

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30 July 2017

Christof Störger

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30 July 2017

David B Mount

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30 July 2017

Hans Gerd Nothwang

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30 July 2017

language of work or name

English

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publication date

1 June 2010

1 reference

Journal of Biological Chemistry

30 July 2017

published in

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30 July 2017

volume

285

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30 July 2017

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30 July 2017

page(s)

23994-24002

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Opposite effect of membrane raft perturbation on transport activity of KCC2 and NKCC1.

30 July 2017

cites work

1 reference

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The potassium chloride cotransporter KCC-2 coordinates development of inhibitory neurotransmission and synapse structure in Caenorhabditis elegans

5 July 2018

1 reference

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Sites of regulated phosphorylation that control K-Cl cotransporter activity

5 July 2018

1 reference

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Intracellular zinc inhibits KCC2 transporter activity

5 July 2018

1 reference

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Chemical crosslinking studies with the mouse Kcc1 K-Cl cotransporter

5 July 2018

1 reference

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Coexpression and heteromerization of two neuronal K-Cl cotransporter isoforms in neonatal brain

5 July 2018

1 reference

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Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2

5 July 2018

1 reference

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A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membrane

5 July 2018

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A novel N-terminal isoform of the neuron-specific K-Cl cotransporter KCC2.

5 July 2018

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Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters

5 July 2018

1 reference

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Oligomerization of KCC2 correlates with development of inhibitory neurotransmission.

5 July 2018

1 reference

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Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

A C-terminal domain in KCC2 confers constitutive K+-Cl- cotransport

5 July 2018

1 reference

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Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters.

5 July 2018

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Regulation of K-Cl cotransport: from function to genes

5 July 2018

1 reference

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Localization of the KCC4 potassium-chloride cotransporter in the nervous system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Quality control in the endoplasmic reticulum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

The K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Molecular, functional, and genomic characterization of human KCC2, the neuronal K-Cl cotransporter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Hyperexcitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Deafness and renal tubular acidosis in mice lacking the K-Cl co-transporter Kcc4.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

A dominant negative mutant of the KCC1 K-Cl cotransporter: both N- and C-terminal cytoplasmic domains are required for K-Cl cotransport activity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Dependence of KCC2 K-Cl cotransporter activity on a conserved carboxy terminus tyrosine residue

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Inhibition of Na(+)-K(+)-2Cl(-) cotransport by mercury

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Mutagenic mapping of the Na-K-Cl cotransporter for domains involved in ion transport and bumetanide binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

An improved PCR-mutagenesis strategy for two-site mutagenesis or sequence swapping between related genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Functional characterization of the neuronal-specific K-Cl cotransporter: implications for [K+]o regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Molecular characterization of a putative K-Cl cotransporter in rat brain. A neuronal-specific isoform

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

Neurogenic role of the depolarizing chloride gradient revealed by global overexpression of KCC2 from the onset of development.

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.144063

Altered chloride homeostasis removes synaptic inhibitory constraint of the stress axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.144063

Identification of key functional domains in the C terminus of the K+-Cl- cotransporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.144063

Transmembrane topology of the secretory Na+-K+-2Cl- cotransporter NKCC1 studied by in vitro translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.144063

Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.144063

Effects of Cys mutation on taurocholic acid transport by mouse ileal and hepatic sodium-dependent bile acid transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.144063

Expression and function of chloride transporters during development of inhibitory neurotransmission in the auditory brainstem.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911324

29 October 2018

Identifiers

DOI

10.1074/JBC.M110.144063

1 reference

30 July 2017

1 reference

30 July 2017

1 reference