Polycomb repressive complex 2 in embryonic stem cells: an overview (Q34025228)

30 July 2017

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title

Polycomb repressive complex 2 in embryonic stem cells: an overview (English)

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30 July 2017

Amanda Jones

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30 July 2017

Hengbin Wang

series ordinal

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30 July 2017

publication date

1 December 2010

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30 July 2017

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

1056-1062

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PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming

30 July 2017

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Polycomb group proteins set the stage for early lineage commitment

5 July 2018

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Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

5 July 2018

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Epigenetic memory in induced pluripotent stem cells

5 July 2018

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ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency

5 July 2018

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Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2.

5 July 2018

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Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.

5 July 2018

1 reference

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Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination

5 July 2018

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Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells

5 July 2018

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Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation

5 July 2018

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Polycomb complexes act redundantly to repress genomic repeats and genes

5 July 2018

1 reference

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Jarid2 and PRC2, partners in regulating gene expression

5 July 2018

1 reference

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A region of the human HOXD cluster that confers polycomb-group responsiveness

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Modifications of RNA polymerase II are pivotal in regulating gene expression states

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Recruitment of polycomb group complexes and their role in the dynamic regulation of cell fate choice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Mechanisms of polycomb gene silencing: knowns and unknowns

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

A vertebrate Polycomb response element governs segmentation of the posterior hindbrain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

The long and the short of it: RNA-directed chromatin asymmetry in mammalian X-chromosome inactivation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Developmental biology. Pluripotent chromatin state

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

PcG proteins, DNA methylation, and gene repression by chromatin looping.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

A novel 6C assay uncovers Polycomb-mediated higher order chromatin conformations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Ubiquitin E3 ligase Ring1b/Rnf2 of polycomb repressive complex 1 contributes to stable maintenance of mouse embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

An extended transcriptional network for pluripotency of embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Polycomb group proteins and long-range gene regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Reprogramming of human somatic cells to pluripotency with defined factors

5 July 2018

1 reference

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A gene regulatory network in mouse embryonic stem cells

5 July 2018

1 reference

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Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs

5 July 2018

1 reference

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

5 July 2018

1 reference

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In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

The polycomb group protein Suz12 is required for embryonic stem cell differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Polycomb/Trithorax response elements and epigenetic memory of cell identity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Polycomb silencing mechanisms and the management of genomic programmes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Polycomb response elements and targeting of Polycomb group proteins in Drosophila.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Genome-wide analysis of Polycomb targets in Drosophila melanogaster

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Control of developmental regulators by Polycomb in human embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Polycomb complexes repress developmental regulators in murine embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Chromatin signatures of pluripotent cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Core transcriptional regulatory circuitry in human embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Analysis of a polycomb group protein defines regions that link repressive activity on nucleosomal templates to in vivo function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Role of histone H2A ubiquitination in Polycomb silencing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Hierarchical recruitment of polycomb group silencing complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

The polycomb-group gene Ezh2 is required for early mouse development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Loss- and gain-of-function mutations show a polycomb group function for Ring1A in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4875077

Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency

5 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-010-0142-7

Induction of pluripotency in human endothelial cells resets epigenetic profile on genome scale.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-010-0142-7

Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-010-0142-7

Prediction and testing of novel transcriptional networks regulating embryonic stem cell self-renewal and commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-010-0142-7

Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-010-0142-7

Chromatin compaction by a polycomb group protein complex

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21213100

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The eed mutation disrupts anterior mesoderm production in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21213100

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S13238-010-0142-7

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

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