Structure--activity relationships of polymyxin antibiotics (Q34010143)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19874036%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

review article

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title

Structure--activity relationships of polymyxin antibiotics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19874036%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19874036%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19874036%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Roger L Nation

1 reference

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11 February 2020

Jian Li

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11 February 2020

language of work or name

English

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publication date

1 March 2010

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Journal of Medicinal Chemistry

11 February 2020

published in

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11 February 2020

volume

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11 February 2020

issue

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11 February 2020

page(s)

1898-1916

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Interactions of lipopolysaccharide and polymyxin studied by NMR spectroscopy

11 February 2020

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5 July 2018

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5 July 2018

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A formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-Amino-4-deoxy-L-arabinose. Identification and function oF UDP-4-deoxy-4-formamido-L-arabinose

5 July 2018

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Evaluation of colistin as an agent against multi-resistant Gram-negative bacteria

5 July 2018

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Temperature dependence of the binding of endotoxins to the polycationic peptides polymyxin B and its nonapeptide

5 July 2018

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5 July 2018

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The search for molecular determinants of LPS inhibition by proteins and peptides.

5 July 2018

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PhoP-regulated Salmonella resistance to the antimicrobial peptides magainin 2 and polymyxin B.

5 July 2018

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Pharmacokinetics of colistin methanesulphonate and colistin in rats following an intravenous dose of colistin methanesulphonate.

5 July 2018

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The relationship between peptide structure and antibacterial activity

5 July 2018

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PmrAB, a two-component regulatory system of Pseudomonas aeruginosa that modulates resistance to cationic antimicrobial peptides and addition of aminoarabinose to lipid A

5 July 2018

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5 July 2018

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Non-ribosomal peptide synthetases as technological platforms for the synthesis of highly modified peptide bioeffectors--Cyclosporin synthetase as a complex example.

5 July 2018

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Cationic antimicrobial peptides activate a two‐component regulatory system, PmrA‐PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in Pseudomonas aeruginosa

5 July 2018

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SODIUM SULPHOMETHYL DERIVATIVES OF POLYMYXINS

5 July 2018

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Stability of colistin and colistin methanesulfonate in aqueous media and plasma as determined by high-performance liquid chromatography.

5 July 2018

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5 July 2018

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An inner membrane enzyme in Salmonella and Escherichia coli that transfers 4-amino-4-deoxy-L-arabinose to lipid A: induction on polymyxin-resistant mutants and role of a novel lipid-linked donor

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Solution structure of polymyxins B and E and effect of binding to lipopolysaccharide: an NMR and molecular modeling study.

5 July 2018

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Surface plasmon resonance studies resolve the enigmatic endotoxin neutralizing activity of polymyxin B.

5 July 2018

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Polymyxin B sulfate and colistin: old antibiotics for emerging multiresistant gram-negative bacteria

5 July 2018

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5 July 2018

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Kinetics of the interaction of endotoxin with polymyxin B and its analogs: a surface plasmon resonance analysis

5 July 2018

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How do peptide synthetases generate structural diversity?

5 July 2018

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PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistance

5 July 2018

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Cationic peptides: a new source of antibiotics

5 July 2018

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The bacterial outer membrane as a drug barrier

5 July 2018

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Titration calorimetric studies to elucidate the specificity of the interactions of polymyxin B with lipopolysaccharides and lipid A.

5 July 2018

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Intermembrane molecular contacts by polymyxin B mediate exchange of phospholipids.

5 July 2018

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Sensitization of Gram-negative bacteria to antibiotics and complement by a nontoxic oligopeptide

5 July 2018

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Structure-Activity Relationship of Colistins

5 July 2018

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5 July 2018

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Preparation of biologically active mono-N-acetyl (14C)-derivatives of the membrane-specific polypeptide antibiotic polymyxin B.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Interaction of polycationic antibiotics with Pseudomonas aeruginosa lipopolysaccharide and lipid A studied by using dansyl-polymyxin

5 July 2018

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The outer membrane permeability-increasing action of linear analogues of polymyxin B nonapeptide

5 July 2018

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The outer membrane permeability-increasing action of deacylpolymyxins

5 July 2018

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Analysis of the binding of polymyxin B to endotoxic lipid A and core glycolipid using a fluorescent displacement probe

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Isolation of two new polymyxin group antibiotics. Studies on antibiotics from the genus Bacillus. XX

5 July 2018

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Polymyxin and Related Peptide Antibiotics

5 July 2018

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The structures of two new polymyxin group antibiotics

5 July 2018

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5 July 2018

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Disruption of Escherichia coli outer membranes by EM 49. A new membrane active peptide antibiotic

5 July 2018

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EM49, a new peptide antibiotic. IV. The structure of EM49

5 July 2018

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Action of Polymyxin B on Bacterial Membranes: Morphological Changes in the Cytoplasm and in the Outer Membrane of Salmonella typhimurium and Escherichia coli B

5 July 2018

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5 July 2018

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Development of des-fatty acyl-polymyxin B decapeptide analogs with Pseudomonas aeruginosa-specific antimicrobial activity

29 October 2018

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Identification of a polymyxin synthetase gene cluster of Paenibacillus polymyxa and heterologous expression of the gene in Bacillus subtilis

29 October 2018

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Contribution of each amino acid residue in polymyxin B(3) to antimicrobial and lipopolysaccharide binding activity

29 October 2018

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Antimicrobial peptides: linking partition, activity and high membrane-bound concentrations.

29 October 2018

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Nosocomial outbreak of infection with pan-drug-resistant Acinetobacter baumannii in a tertiary care university hospital

29 October 2018

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Comparison of the structure and dynamics of the antibiotic peptide polymyxin B and the inactive nonapeptide in aqueous trifluoroethanol by NMR spectroscopy

29 October 2018

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Capsule polysaccharide is a bacterial decoy for antimicrobial peptides.

29 October 2018

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In vitro pharmacodynamics of colistin against multidrug-resistant Klebsiella pneumoniae

29 October 2018

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Pandrug-resistant Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii infections: characteristics and outcome in a series of 28 patients

29 October 2018

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Semi-synthesis of polymyxin B (2-10) and colistin (2-10) analogs employing the Trichloroethoxycarbonyl (Troc) group for side chain protection of alpha,gamma-diaminobutyric acid residues

29 October 2018

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Colistin-resistant isolates of Klebsiella pneumoniae emerging in intensive care unit patients: first report of a multiclonal cluster

29 October 2018

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Thermodynamic analysis of the lipopolysaccharide-dependent resistance of gram-negative bacteria against polymyxin B.

29 October 2018

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Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides.

29 October 2018

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Discovery of new potent human protein tyrosine phosphatase inhibitors via pharmacophore and QSAR analysis followed by in silico screening.

29 October 2018

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Membrane association and contact formation by a synthetic analogue of polymyxin B and its fluorescent derivatives.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907661

Synthesis and membrane action of polymyxin B analogues

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907661

Steady-state pharmacokinetics of intravenous colistin methanesulphonate in patients with cystic fibrosis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907661

Solid-phase synthesis of polymyxin B1 and analogues via a safety-catch approach

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907661

Modulation of the hydrophobic domain of polymyxin B nonapeptide: effect on outer-membrane permeabilization and lipopolysaccharide neutralization.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907661

Cyclization of backbone-substituted peptides catalyzed by the thioesterase domain from the tyrocidine nonribosomal peptide synthetase

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907661

Thermodynamics and Structural Studies of the Interaction of Polymyxin B with Deep Rough Mutant Lipopolysaccharides

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907661

Antibacterial peptides and the outer membranes of gram-negative bacilli

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907661

Polymyxin B octapeptide and polymyxin B heptapeptide are potent outer membrane permeability-increasing agents

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907661

Studies on the selectivity of action of colistin, colistin nonapeptide and colistin heptapeptide on the cell envelope of Escherichia coli

29 October 2018

1 reference

12 December 2020

EM49, a new peptide antibiotic. I. Fermentation, isolation, and preliminary characterization

1 reference

12 December 2020

Specificity for the exchange of phospholipids through polymyxin B mediated intermembrane molecular contacts

1 reference

12 December 2020

[Syntheses in the polymyxin series. 11. Synthesis of circulin A]

1 reference

12 December 2020

Antibiograms of multidrug-resistant clinical Acinetobacter baumannii: promising therapeutic options for treatment of infection with colistin-resistant strains

1 reference

12 December 2020

Returning to the pre-antibiotic era in the critically ill: The XDR problem*

1 reference

12 December 2020

Gram-negative outer and inner membrane models: insertion of cyclic cationic lipopeptides

1 reference

12 December 2020

Old polymyxins are back: is resistance close?

1 reference

12 December 2020

Essential amino groups of polymyxin B

1 reference

12 December 2020

Direct vesicle-vesicle exchange of phospholipids mediated by polymyxin B

1 reference

12 December 2020

Total synthesis of two cyclodecapeptides exerting polymyxin-like activity

1 reference

12 December 2020

EM49: a new polypeptide antibiotic active against cell membranes

1 reference

12 December 2020

Selective cleavage of a peptide antibiotic, colistin by colistinase

1 reference

12 December 2020

Characterization of lipopolysaccharides of polymyxin-resistant and polymyxin-sensitive Klebsiella pneumoniae O3

1 reference

12 December 2020

Isolation of octapeptin D (studies on antibiotics from the genus Bacillus. XXVII)

1 reference

12 December 2020

Molecular mapping and detoxification of the lipid A binding site by synthetic peptides

1 reference

12 December 2020

Conformation of polymyxin B analogs in DMSO from NMR spectra and molecular modeling

1 reference

12 December 2020

Synthesis and characterization of the colistin peptide polymyxin E1 and related antimicrobial peptides

1 reference

12 December 2020

Facile synthesis of Nalpha-protected-L-alpha,gamma-diaminobutyric acids mediated by polymer-supported hypervalent iodine reagent in water

1 reference

12 December 2020

Selective chemical modifications of polymyxin B

1 reference

12 December 2020

Bu-2470, a new peptide antibiotic complex. II. Structure determination of Bu-2470 A, B1, B2a and B2b

1 reference

12 December 2020

Pharmacokinetics of novel antimicrobial cationic peptides NAB 7061 and NAB 739 in rats following intravenous administration

1 reference

12 December 2020

Structure-function studies of polymyxin B nonapeptide: implications to sensitization of gram-negative bacteria

1 reference

12 December 2020

The functional association of polymyxin B with bacterial lipopolysaccharide is stereospecific: studies on polymyxin B nonapeptide

1 reference

12 December 2020

Colistin-associated acute renal failure: revisited

1 reference

12 December 2020

N-terminal modifications of Polymyxin B nonapeptide and their effect on antibacterial activity

1 reference

12 December 2020

Carbon-13 NMR studies of EM 49 and related octapeptins

1 reference

12 December 2020

Isolation and characterization of three new polymyxins in polymyxins B and E by high-performance liquid chromatography

1 reference

12 December 2020

1 reference

12 December 2020

EM49, a new peptide antibiotic. II. Chemical characterization

1 reference

12 December 2020

Solid-phase total synthesis of polymyxin B1

1 reference

12 December 2020

Identifiers

DOI

10.1021/JM900999H

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19874036%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19874036%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

19874036

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19874036%20AND%20SRC:MED&resulttype=core&format=json