Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline (Q34017163)

30 July 2017

title

Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline (English)

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30 July 2017

main subject

metabolomic profiling

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Steven H Zeisel

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30 July 2017

Wei Sha

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30 July 2017

Kerry-Ann da Costa

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30 July 2017

Leslie M Fischer

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30 July 2017

Michael V Milburn

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30 July 2017

Kay A Lawton

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30 July 2017

Alvin Berger

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30 July 2017

Wei Jia

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30 July 2017

language of work or name

English

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publication date

6 April 2010

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30 July 2017

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

2962-2975

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Metabolomics approaches for discovering biomarkers of drug-induced hepatotoxicity and nephrotoxicity

30 July 2017

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Effect of choline deficiency on S-adenosylmethionine and methionine concentrations in rat liver

5 July 2018

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Choline, an essential nutrient for humans

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Plasma palmitoleic acid, a product of stearoyl-coA desaturase activity, is an independent marker of triglyceridemia and abdominal adiposity.

29 October 2018

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Effects of orange juice and proline betaine on glycine betaine and homocysteine in healthy male subjects.

29 October 2018

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Metabolomics (liver and blood profiling) in a mouse model in response to fasting: a study of hepatic steatosis

29 October 2018

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Maternal nutrient intakes and risk of orofacial clefts.

29 October 2018

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Metabolic assessment of human liver transplants from biopsy samples at the donor and recipient stages using high-resolution magic angle spinning 1H NMR spectroscopy

29 October 2018

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Metabonomic evaluation of idiosyncrasy-like liver injury in rats cotreated with ranitidine and lipopolysaccharide

29 October 2018

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Stearoyl-CoA desaturase 1 deficiency increases CTP:choline cytidylyltransferase translocation into the membrane and enhances phosphatidylcholine synthesis in liver

29 October 2018

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Choline- and betaine-defined diets for use in clinical research and for the management of trimethylaminuria

29 October 2018

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An integrated reverse functional genomic and metabolic approach to understanding orotic acid-induced fatty liver

29 October 2018

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Quantitation of choline and its metabolites in tissues and foods by liquid chromatography/electrospray ionization-isotope dilution mass spectrometry

29 October 2018

1 reference

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29 October 2018

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29 October 2018

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Choline deficiency causes reversible hepatic abnormalities in patients receiving parenteral nutrition: proof of a human choline requirement: a placebo-controlled trial

29 October 2018

1 reference

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29 October 2018

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Prolonged fasting in humans results in diminished plasma choline concentrations but does not cause liver dysfunction.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909293

Restricting food intake does not exacerbate the effects of a choline-deficient diet on tissue carnitine concentrations in rats.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909293

Isovalerylcarnitine is a specific activator of the high calcium requiring calpain forms

29 October 2018

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12 December 2020

Effects of choline deficiency and methotrexate treatment upon liver folate content and distribution

1 reference

12 December 2020

Accumulation of 1,2-sn-diradylglycerol with increased membrane-associated protein kinase C may be the mechanism for spontaneous hepatocarcinogenesis in choline-deficient rats

1 reference

12 December 2020

Severe folate deficiency causes secondary depletion of choline and phosphocholine in rat liver

1 reference

12 December 2020

Choline deficiency: a cause of hepatic steatosis during parenteral nutrition that can be reversed with intravenous choline supplementation

1 reference

12 December 2020

Expression of phosphatidylethanolamine N-methyltransferase-2 is markedly enhanced in long term choline-deficient rats

1 reference

12 December 2020

Introduction of fast MR imaging in the assessment of hepatic steatosis

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12 December 2020

Plasma choline concentration in humans fed parenterally

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12 December 2020

Renal Tubular Drug Transporters

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12 December 2020

No association between polymorphism in PEMT (V175M) and hepatic triglyceride content in the Dallas Heart Study

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12 December 2020

Physiology, structure, and regulation of the cloned organic anion transporters

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12 December 2020

Identifiers

DOI

10.1096/FJ.09-154054

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30 July 2017

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30 July 2017

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