The role of the interleukin-1/Toll-like receptor superfamily in inflammation and host defence (Q34016439)

30 July 2017

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title

The role of the interleukin-1/Toll-like receptor superfamily in inflammation and host defence (English)

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30 July 2017

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L A O'Neill

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30 July 2017

K A Fitzgerald

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30 July 2017

publication date

1 July 2000

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30 July 2017

published in

Microbes and Infection

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

933-943

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Interleukin 1 signaling occurs exclusively via the type I receptor

30 July 2017

cites work

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A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types

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Drosophila Toll and IL-1 receptor

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The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

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MyD88, an adapter protein involved in interleukin-1 signaling

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MyD88: An Adapter That Recruits IRAK to the IL-1 Receptor Complex

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The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.

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7 January 2021

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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7 January 2021

A family of human receptors structurally related to Drosophila Toll

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7 January 2021

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

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7 January 2021

Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants

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7 January 2021

IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP

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7 January 2021

Purification and Characterization of the Human Interleukin-18 Receptor

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7 January 2021

A newly defined interleukin-1?

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Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling

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7 January 2021

Defective NK cell activity and Th1 response in IL-18-deficient mice

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7 January 2021

Cloning of a cDNA encoding a novel interleukin-1 receptor related protein (IL 1R-rp2)

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7 January 2021

Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily

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7 January 2021

Serum- and oncoprotein-mediated induction of a gene with sequence similarity to the gene encoding carcinoembryonic antigen

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7 January 2021

A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor

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7 January 2021

Cloning of a putative ligand for the T1/ST2 receptor

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7 January 2021

T1/ST2 signaling establishes it as a member of an expanding interleukin-1 receptor family

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7 January 2021

Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses.

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7 January 2021

A new member of the IL-1 receptor family highly expressed in hippocampus and involved in X-linked mental retardation

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7 January 2021

A soluble receptor for interleukin-1 beta encoded by vaccinia virus: a novel mechanism of virus modulation of the host response to infection

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7 January 2021

The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense

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7 January 2021

Toll homologue expression in the beetle tribolium suggests a different mode of dorsoventral patterning than in drosophila embryos.

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7 January 2021

TLR6: A novel member of an expanding toll-like receptor family

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7 January 2021

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

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7 January 2021

Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide

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7 January 2021

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

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7 January 2021

Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium

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7 January 2021

The role of B7 costimulation in T-cell immunity.

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7 January 2021

Recognition of gram-negative bacteria and endotoxin by the innate immune system

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7 January 2021

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

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7 January 2021

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

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7 January 2021

Two-way trafficking with Ran.

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7 January 2021

Lps(d)/Ran of endotoxin-resistant C3H/HeJ mice is defective in mediating lipopolysaccharide endotoxin responses

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7 January 2021

Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors

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7 January 2021

Extracellular morphogens in Drosophila embryonic dorsal-ventral patterning

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7 January 2021

Signal transduction by a protease cascade

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7 January 2021

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7 January 2021

Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila

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7 January 2021

New types of clotting factors and defense molecules found in horseshoe crab hemolymph: their structures and functions

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7 January 2021

Toll, a new piece in the puzzle of innate immunity

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7 January 2021

The product of the tobacco mosaic virus resistance gene N: similarity to toll and the interleukin-1 receptor

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7 January 2021

The L6 gene for flax rust resistance is related to the Arabidopsis bacterial resistance gene RPS2 and the tobacco viral resistance gene N.

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7 January 2021

Three genes of the Arabidopsis RPP1 complex resistance locus recognize distinct Peronospora parasitica avirulence determinants.

1 reference

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7 January 2021

The Arabidopsis downy mildew resistance gene RPP5 shares similarity to the toll and interleukin-1 receptors with N and L6.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2800%2900396-8

7 January 2021

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2800%2900396-8

7 January 2021

Unresponsiveness of MyD88-deficient mice to endotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2800%2900396-8

7 January 2021

Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2800%2900396-8

7 January 2021

A Drosophila TNF-receptor-associated factor (TRAF) binds the ste20 kinase Misshapen and activates Jun kinase

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https://api.crossref.org/works/10.1016%2FS1286-4579%2800%2900396-8

7 January 2021

ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway

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https://api.crossref.org/works/10.1016%2FS1286-4579%2800%2900396-8

7 January 2021

The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation

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https://api.crossref.org/works/10.1016%2FS1286-4579%2800%2900396-8

7 January 2021

10.1016/S1286-4579(00)00396-8

Identifiers

DOI

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30 July 2017

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