A novel interaction of CLN3 with nonmuscle myosin-IIB and defects in cell motility of Cln3(-/-) cells (Q34014206)

30 July 2017

title

A novel interaction of CLN3 with nonmuscle myosin-IIB and defects in cell motility of Cln3(-/-) cells (English)

1 reference

CLN3 lysosomal/endosomal transmembrane protein, battenin

30 July 2017

main subject

1 reference

regulation of cytoskeleton organization

GOA release 2020-03-11

1 reference

Myosin, heavy polypeptide 10, non-muscle

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Amanda L Getty

series ordinal

1 reference

30 July 2017

Jared W Benedict

series ordinal

1 reference

30 July 2017

David A Pearce

series ordinal

1 reference

30 July 2017

language of work or name

English

0 references

publication date

17 September 2010

1 reference

Experimental Cell Research

30 July 2017

published in

1 reference

30 July 2017

volume

317

1 reference

30 July 2017

1 reference

30 July 2017

page(s)

51-69

1 reference

describes a project that uses

30 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4124749/fullTextXML

inferred from PubMed Central ID database lookup

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

1 reference

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Nonmuscle myosin IIA and IIB have distinct functions in the exocytosis-dependent process of cell membrane repair

28 July 2018

1 reference

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

1 reference

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28 July 2018

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28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124749

CLN3 protein regulates lysosomal pH and alters intracellular processing of Alzheimer's amyloid-beta protein precursor and cathepsin D in human cells

28 July 2018

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28 July 2018

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28 July 2018

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Studies of pH regulation by Btn1p, the yeast homolog of human Cln3p

28 July 2018

1 reference

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CLN3 defines a novel antiapoptotic pathway operative in neurodegeneration and mediated by ceramide

28 July 2018

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Specific alterations in levels of mannose 6-phosphorylated glycoproteins in different neuronal ceroid lipofuscinoses

28 July 2018

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Nonmuscle myosin II-B is required for normal development of the mouse heart

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124749

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28 July 2018

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28 July 2018

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Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity

28 July 2018

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Isolation of a novel gene underlying Batten disease, CLN3. The International Batten Disease Consortium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124749

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124749

Chloroquine and monensin inhibit induction of DNA synthesis in rat arterial smooth muscle cells stimulated with platelet-derived growth factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124749

Altered arginine metabolism in the central nervous system (CNS) of the Cln3-/- mouse model of juvenile Batten disease

28 July 2018

1 reference

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Loss of the Batten disease gene CLN3 prevents exit from the TGN of the mannose 6-phosphate receptor.

29 October 2018

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Btn1 affects cytokinesis and cell-wall deposition by independent mechanisms, one of which is linked to dysregulation of vacuole pH.

29 October 2018

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Toxicity and endocytosis of spinocerebellar ataxia type 6 polyglutamine domains: role of myosin IIb.

29 October 2018

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A novel role of the Batten disease gene CLN3: association with BMP synthesis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124749

Nonmuscle myosins II-B and Va are components of detergent-resistant membrane skeletons derived from mouse forebrain

29 October 2018

1 reference

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A critical role for myosin IIb in dendritic spine morphology and synaptic function

29 October 2018

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Blebbistatin, a novel inhibitor of myosin II ATPase activity, increases aqueous humor outflow facility in perfused enucleated porcine eyes.

29 October 2018

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Thalamocortical neuron loss and localized astrocytosis in the Cln3Deltaex7/8 knock-in mouse model of Batten disease

29 October 2018

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Autoimmunity to glutamic acid decarboxylase in the neurodegenerative disorder Batten disease

29 October 2018

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Late onset neurodegeneration in the Cln3-/- mouse model of juvenile neuronal ceroid lipofuscinosis is preceded by low level glial activation.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124749

A galactosylceramide binding domain is involved in trafficking of CLN3 from Golgi to rafts via recycling endosomes

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124749

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29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124749

A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124749

Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability.

29 October 2018

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Early changes in gene expression in two models of Batten disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124749

Nonmuscle myosin heavy chain IIA mutations define a spectrum of autosomal dominant macrothrombocytopenias: May-Hegglin anomaly and Fechtner, Sebastian, Epstein, and Alport-like syndromes.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124749

Mammalian neural stem cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124749

Action of BTN1, the yeast orthologue of the gene mutated in Batten disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4124749

The neuronal ceroid-lipofuscinoses

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20850431

12 December 2020

inferred from PubMed ID database lookup

Myosin IIB is required for growth cone motility

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20850431

12 December 2020

inferred from PubMed ID database lookup

The structural basis of blebbistatin inhibition and specificity for myosin II

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20850431

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.YEXCR.2010.09.007

1 reference

30 July 2017

1 reference

30 July 2017

1 reference