Mitochondrial targeting of electron scavenging antioxidants: regulation of selective oxidation vs random chain reactions (Q23923177)

HELD

1 reference

25 September 2023

1 reference

29 March 2020

1 reference

Naveena V. K. Yanamala

0 references

Detcho Stoyanovsky

0 references

Judith Klein-Seetharaman

Judith Klein-Seetharaman

0 references

Hülya Bayır

Hülya Bayir

0 references

Peter Wipf

Peter Wipf

0 references

Anna A. Shvedova

Anna A Shvedova

0 references

Valerian E. Kagan

Valerian E Kagan

0 references

Yulia Y. Tyurina

Yulia Y Tyurina

0 references

Natalia A. Belikova

Natalia A Belikova

0 references

Jianfei Jiang

Jianfei Jiang

0 references

Joel S Greenberger

Joel S Greenberger

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author name string

Grigory Borisenko

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Alejandro K Samhan Arias

0 references

Muhammad A Tungekar

0 references

Jing Ji

0 references

Bruce R Pitt

Advanced Drug Delivery Reviews

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language of work or name

English

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publication date

30 November 2009

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published in

1 reference

8 December 2019

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0 references

1375-85

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on focus list of Wikimedia project

Wikimedia–NIOSH collaboration

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2 references

2 February 2024

inferred from email address

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Mitochondrial targeting of a catalase transgene product by plasmid liposomes increases radioresistance in vitro and in vivo

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Mitochondria-targeted (2-hydroxyamino-vinyl)-triphenyl-phosphonium releases NO(.) and protects mouse embryonic cells against irradiation-induced apoptosis

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27 September 2017

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27 September 2017

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The mitochondrial antioxidants MitoE(2) and MitoQ(10) increase mitochondrial Ca(2+) load upon cell stimulation by inhibiting Ca(2+) efflux from the organelle

27 September 2017

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Mitochondria-targeted antioxidants in the treatment of disease

27 September 2017

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Evidence of oxidative stress in Alzheimer's disease brain and antioxidant therapy: lights and shadows

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Effect of high-dose alpha-tocopherol supplementation on biomarkers of oxidative stress and inflammation and carotid atherosclerosis in patients with coronary artery disease

27 September 2017

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High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates

27 September 2017

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Reactive oxygen species in mitochondria-mediated cell death

27 September 2017

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Mitochondriotropics: a review of their mode of action, and their applications for drug and DNA delivery to mammalian mitochondria

27 September 2017

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MitoQ--a mitochondria-targeted antioxidant.

27 September 2017

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27 September 2017

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Oxidative stress modulation and T cell activation

27 September 2017

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Hemigramicidin-TEMPO conjugates: novel mitochondria-targeted anti-oxidants

27 September 2017

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Mitochondria and reactive oxygen species in renal cancer.

27 September 2017

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The chemistry and biology of nitroxide compounds

27 September 2017

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Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage.

27 September 2017

1 reference

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Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases

27 September 2017

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Structural requirements for optimized delivery, inhibition of oxidative stress, and antiapoptotic activity of targeted nitroxides

27 September 2017

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Cell-permeable, mitochondrial-targeted, peptide antioxidants

27 September 2017

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Free radical production requires both inducible nitric oxide synthase and xanthine oxidase in LPS-treated skin

27 September 2017

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27 September 2017

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pH-Dependent interaction of cytochrome c with mitochondrial mimetic membranes: the role of an array of positively charged amino acids.

27 September 2017

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Reactive oxygen species in the cerebral circulation: physiological roles and therapeutic implications for hypertension and stroke

27 September 2017

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ROS stress in cancer cells and therapeutic implications

27 September 2017

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27 September 2017

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Reactive oxygen species in the initiation of IL-4 driven autoimmunity as a potential therapeutic target

27 September 2017

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Oxidative stress in cardiovascular disease: myth or fact?

27 September 2017

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Mitochondrial localization of superoxide dismutase is required for decreasing radiation-induced cellular damage

27 September 2017

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Mechanism of free radical oxygenation of polyunsaturated fatty acids by cyclooxygenases

27 September 2017

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Antioxidant vitamins and risk of cardiovascular disease. Review of large-scale randomised trials

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Oxygen free radicals and systemic autoimmunity

27 September 2017

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Manganese superoxide dismutase (SOD2) inhibits radiation-induced apoptosis by stabilization of the mitochondrial membrane

27 September 2017

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Mitochondria as subcellular targets for clinically useful anthracyclines

27 September 2017

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Liposomes as immunomodulator--inhibitory effect of liposomes on NO production from macrophages

27 September 2017

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Radiation, radicals, and images

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Selective targeting of an antioxidant to mitochondria

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Cardiolipin: biosynthesis, remodeling and trafficking in the heart and mammalian cells (Review).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Formation and properties of peroxynitrite as studied by laser flash photolysis, high-pressure stopped-flow technique, and pulse radiolysis

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease

27 September 2017

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In vivo spin trapping of xenobiotic free radical metabolites

27 September 2017

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In vivo detection of radical adducts by electron spin resonance

27 September 2017

1 reference

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Detection of oxygen-derived radicals in biological systems using electron spin resonance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Oxidants in mitochondria: from physiology to diseases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Intramitochondrial dyes allow selective in vitro photolysis of carcinoma cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

A comparative model membrane study on structural effects of membrane-active positively charged anti-tumor drugs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Biochemical mechanisms for oxygen free radical formation during exercise

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Free radicals and the action of inhibitors of radical processes under pathological states and ageing in living organisms and in man

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Role of ubiquinone in the mitochondrial generation of hydrogen peroxide

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

AA1, a newly synthesized monovalent lipophilic cation, expresses potent in vivo antitumor activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

A mitochondria-targeted nitroxide is reduced to its hydroxylamine by ubiquinol in mitochondria

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

A permeability barrier in mitochondria in ;high-energy states' against positively charged disulphides

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

ATP specifically drives refolding of non-native conformations of cytochrome c.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Alpha-tocopherol (vitamin E) and beta-carotene supplementation does not affect the risk for large abdominal aortic aneurysm in a controlled trial

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Kinetics and mechanisms of catalase in peroxisomes of the mitochondrial fraction

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

The effect of phenyl tert-butyl nitrone (PBN) on CCl4-induced rat liver injury detected by proton magnetic resonance imaging (MRI) in vivo and electron microscopy (EM).

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Nitric oxide, an inhibitor of lipid oxidation by lipoxygenase, cyclooxygenase and hemoglobin

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Kinetics of superoxide scavenging by dismutase enzymes and manganese mimics determined by electron spin resonance

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Divergence to apoptosis from ROS induced cell cycle arrest: effect of cadmium.

30 May 2018

1 reference

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ATP acts as a regulatory effector in modulating structural transitions of cytochrome c: implications for apoptotic activity

29 November 2018

1 reference

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Development of mitochondria-targeted derivatives of resveratrol

29 November 2018

1 reference

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Activation of NO donors in mitochondria: peroxidase metabolism of (2-hydroxyamino-vinyl)-triphenyl-phosphonium by cytochrome c releases NO and protects cells against apoptosis

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Mitochondrial redox cycling of mitoquinone leads to superoxide production and cellular apoptosis.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Cardiolipin-specific peroxidase reactions of cytochrome C in mitochondria during irradiation-induced apoptosis

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Mitochondrial targeting of selective electron scavengers: synthesis and biological analysis of hemigramicidin-TEMPO conjugates

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Mitochondria superoxide dismutase mimetic inhibits peroxide-induced oxidative damage and apoptosis: role of mitochondrial superoxide

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Remodeling of cardiolipin by phospholipid transacylation.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Essential role of complex II of the respiratory chain in hypoxia-induced ROS generation in the pulmonary vasculature.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

A pharmacological analysis elucidating why, in contrast to (-)-deprenyl (selegiline), alpha-tocopherol was ineffective in the DATATOP study

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Synthesis of isotopically labeled arachidonic acids to probe the reaction mechanism of prostaglandin H synthase

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Selective targeting of synthetic antioxidants to mitochondria: towards a mitochondrial medicine for neurodegenerative diseases?

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Glutathione depletion enforces the mitochondrial permeability transition and causes cell death in Bcl-2 overexpressing HL60 cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Oxidation of the ketoxime acetoxime to nitric oxide by oxygen radical-generating systems

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Evidence of a specific complex between adriamycin and negatively-charged phospholipids.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2784017

Treatment with a novel hemigramicidin-TEMPO conjugate prolongs survival in a rat model of lethal hemorrhagic shock

29 November 2018

1 reference

12 December 2020

Synthesis and characterization of thiobutyltriphenylphosphonium bromide, a novel thiol reagent targeted to the mitochondrial matrix

1 reference

12 December 2020

Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria

1 reference

12 December 2020

Identification of free radical formation and F2-isoprostanes in vivo by acute Cr(VI) poisoning

1 reference

12 December 2020

Acute methanol intoxication generates free radicals in rats: an ESR spin trapping investigation

1 reference

12 December 2020

para-Substituted N-nitroso-N-oxybenzenamine ammonium salts: a new class of redox-sensitive nitric oxide releasing compounds

1 reference

12 December 2020

Chemiluminescence associated with doxorubicin-induced lipid peroxidation in rat heart mitochondria

1 reference

12 December 2020

Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury

1 reference

12 December 2020

Inhibition of rat colon tumor isograft growth with dequalinium chloride

1 reference

12 December 2020

Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)

1 reference

12 December 2020

Controlled trial of alpha-tocopherol and beta-carotene supplements on stroke incidence and mortality in male smokers

1 reference

12 December 2020

Vitamin E supplementation and cardiovascular events in high-risk patients

1 reference

12 December 2020

Primary physico-chemical mechanisms of radiation injury

1 reference

12 December 2020

Mechanism of Coupling of Oxidative Phosphorylation and the Membrane Potential of Mitochondria

1 reference

12 December 2020

Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide

1 reference

12 December 2020

10.1016/J.ADDR.2009.06.008

Identifiers

DOI

1 reference

NIOSHTIC-2 ID

20036250

0 references

1 reference

1 reference

PubMed publication ID

19716396

1 reference