Regulation of angiogenesis and tumor growth by p110 alpha and AKT1 via VEGF expression (Q23910931)

Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology

21 January 2018

1 reference

PTEN protein expression correlates with PTEN gene molecular changes but not with VEGF expression in astrocytomas.

21 January 2018

1 reference

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

21 January 2018

1 reference

Expression, purification, characterization and homology modeling of active Akt/PKB, a key enzyme involved in cell survival signaling

21 January 2018

1 reference

Signal pathway profiling of ovarian cancer from human tissue specimens using reverse‐phase protein microarrays

21 January 2018

1 reference

7 January 2021

Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins

1 reference

7 January 2021

Epidemiology of ovarian cancer: a status report

1 reference

7 January 2021

Phosphoinositide kinases

1 reference

7 January 2021

A target for phosphoinositide 3-kinase: Akt/PKB.

1 reference

7 January 2021

Phosphoinositide kinases

1 reference

7 January 2021

Phosphoinositide 3 kinase is critical for survival, mitogenesis and migration but not for differentiation of endothelial cells

1 reference

7 January 2021

PIK3CA: determining its role in cellular proliferation and ovarian cancer

1 reference

7 January 2021

Expression of a mutated form of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase in a Hodgkin's lymphoma-derived cell line (CO).

1 reference

7 January 2021

PIK3CA as an oncogene in cervical cancer

1 reference

7 January 2021

PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas.

1 reference

7 January 2021

Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3

1 reference

7 January 2021

Tumor angiogenesis: therapeutic implications

1 reference

7 January 2021

Transplacental carcinogenesis by stilbestrol

1 reference

7 January 2021

Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells

1 reference

7 January 2021

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

1 reference

7 January 2021

Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways

1 reference

7 January 2021

Both v-Ha-Ras and v-Raf Stimulate Expression of the Vascular Endothelial Growth Factor in NIH 3T3 Cells

1 reference

7 January 2021

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

1 reference

7 January 2021

Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells

1 reference

7 January 2021

The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling

1 reference

7 January 2021

Vascular endothelial growth factor induces expression of connective tissue growth factor via KDR, Flt1, and phosphatidylinositol 3-kinase-akt-dependent pathways in retinal vascular cells

1 reference

7 January 2021

Identification of tyrosine residues in vascular endothelial growth factor receptor-2/FLK-1 involved in activation of phosphatidylinositol 3-kinase and cell proliferation

1 reference

7 January 2021

Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription

1 reference

7 January 2021

Altered signaling and cell cycle regulation in embryonal stem cells with a disruption of the gene for phosphoinositide 3-kinase regulatory subunit p85alpha

1 reference

7 January 2021

Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling

1 reference

7 January 2021

Involvement of PI3K and MAPK signaling in bcl-2-induced vascular endothelial growth factor expression in melanoma cells

1 reference

7 January 2021

Vascular endothelial growth factor (VEGF) and its receptors

1 reference

7 January 2021

Apigenin inhibits VEGF and HIF-1 expression via PI3K/AKT/p70S6K1 and HDM2/p53 pathways.

1 reference

7 January 2021

Treatment of patients with early epithelial ovarian cancer

1 reference

7 January 2021

Chemotherapy for early ovarian cancer

1 reference

7 January 2021

Phosphatidylinositol-3 kinase inhibitors reproduce the selective antiproliferative effects of imatinib on chronic myeloid leukaemia progenitor cells

1 reference

7 January 2021

9-beta-D-arabinofuranosyl-2-fluoroadenine inhibits expression of vascular endothelial growth factor through hypoxia-inducible factor-1 in human ovarian cancer cells

1 reference

7 January 2021

High frequency of mutations of the PIK3CA gene in human cancers

1 reference

7 January 2021

Akt signaling: linking membrane events to life and death decisions

1 reference

7 January 2021

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

1 reference

7 January 2021

HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

1 reference

7 January 2021

G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells

1 reference

7 January 2021

Topical treatment with inhibitors of the phosphatidylinositol 3'-kinase/Akt and Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways reduces melanoma development in severe combined immunodeficient mice

1 reference

7 January 2021

Mutations of PIK3CA in Anaplastic Oligodendrogliomas, High-Grade Astrocytomas, and Medulloblastomas

1 reference

7 January 2021

Mutation of the PIK3CA gene in ovarian and breast cancer

1 reference

7 January 2021

Inhibition of inhibitor of nuclear factor-kappaB phosphorylation increases the efficacy of paclitaxel in in vitro and in vivo ovarian cancer models

1 reference

7 January 2021

The biology and clinical relevance of the PTEN tumor suppressor pathway

1 reference

7 January 2021

The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas

1 reference

7 January 2021

VEGF receptor signaling in tumor angiogenesis

1 reference

7 January 2021

Prospects for phosphoinositide 3-kinase inhibition as a cancer treatment

1 reference

7 January 2021

Oncogenic mutations of PIK3CA in human cancers

1 reference

7 January 2021