Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta (Q22254263)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856244%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta (English)

1 reference

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7 November 2019

1 reference

R L Williams

R L

Williams

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7 November 2019

T H Rabbitts

T H

Rabbitts

1 reference

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7 November 2019

A J Warren

A J

Warren

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7 November 2019

J Bravo

series ordinal

author given names

author last names

Bravo

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7 November 2019

language of work or name

English

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publication date

1 June 2000

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7 November 2019

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7 November 2019

volume

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7 November 2019

issue

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7 November 2019

page(s)

3004-3015

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Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

7 November 2019

cites work

1 reference

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Sequence specificity of the core-binding factor

19 March 2017

1 reference

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Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

19 March 2017

1 reference

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

19 March 2017

1 reference

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The Ig fold of the core binding factor alpha Runt domain is a member of a family of structurally and functionally related Ig-fold DNA-binding domains

19 March 2017

1 reference

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Solution structure of core binding factor beta and map of the CBF alpha binding site

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Molecular insights into PEBP2/CBF beta-SMMHC associated acute leukemia revealed from the structure of PEBP2/CBF beta

19 March 2017

1 reference

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Immunoglobulin motif DNA recognition and heterodimerization of the PEBP2/CBF Runt domain

19 March 2017

1 reference

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Three-dimensional structure of the Stat3beta homodimer bound to DNA

19 March 2017

1 reference

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Structure of NF-kappa B p50 homodimer bound to a kappa B site

19 March 2017

1 reference

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The CCP4 suite: programs for protein crystallography

19 March 2017

1 reference

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Automated MAD and MIR structure solution

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

19 March 2017

1 reference

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SCOP: a structural classification of proteins database for the investigation of sequences and structures

19 March 2017

1 reference

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Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): a vehicle for direct determination of three-dimensional structure

19 March 2017

1 reference

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Improved methods for building protein models in electron density maps and the location of errors in these models

19 March 2017

1 reference

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

19 March 2017

1 reference

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Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

The immunoglobulin fold. Structural classification, sequence patterns and common core

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Over-production of proteins in Escherichia coli: mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Molecular basis of tissue-specific gene expression mediated by the runt domain transcription factor PEBP2/CBF.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Mutation analysis of core binding factor A1 in patients with cleidocranial dysplasia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Differential interactions between Brother proteins and Runt domain proteins in the Drosophila embryo and eye.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Drosophila homologs of the proto-oncogene product PEBP2/CBF beta regulate the DNA-binding properties of Runt

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Differential protein binding in lymphocytes to a sequence in the enhancer of the mouse retrovirus SL3-3.

27 September 2017

1 reference

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Purification of a mouse nuclear factor that binds to both the A and B cores of the polyomavirus enhancer

27 September 2017

1 reference

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Translocations, master genes, and differences between the origins of acute and chronic leukemias

27 September 2017

1 reference

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Oncogenic conversion of transcription factors by chromosomal translocations

27 September 2017

1 reference

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t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Functional domains of the t(8;21) fusion protein, AML-1/ETO.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

27 September 2017

1 reference

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Oncogenic Transcription Factors in the Human Acute Leukemias

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

A simple screening for mutant DNA binding proteins: application to murine transcription factor PEBP2alpha subunit, a founding member of the Runt domain protein family

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Redox regulation of the DNA binding activity in transcription factor PEBP2. The roles of two conserved cysteine residues

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Biochemical and biophysical properties of the core-binding factor alpha2 (AML1) DNA-binding domain

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Chromosomal translocations in human cancer.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203359

Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2alphaB gene associated with myeloblastic leukemias

29 November 2018

1 reference

12 December 2020

CBFA1 Mutation Analysis and Functional Correlation with Phenotypic Variability in Cleidocranial Dysplasia

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

Functional dissection of the alpha and beta subunits of transcription factor PEBP2 and the redox susceptibility of its DNA binding activity

1 reference

12 December 2020

Treatment of multiwavelength anomalous diffraction data as a special case of multiple isomorphous replacement

1 reference

12 December 2020

The Immunoglobulin Fold

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/19.12.3004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856244%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856244%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

PubMed publication ID

10856244

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856244%20AND%20SRC:MED&resulttype=core&format=json