The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61beta and a cytosolic, deglycosylated intermediary (Q22004173)

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English	The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61beta and a cytosolic, deglycosylated intermediary	scientific article

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scholarly article

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The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61beta and a cytosolic, deglycosylated intermediary (English)

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endoplasmic reticulum

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transmembrane transport

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cystic fibrosis

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transmembrane protein

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Sec61 translocon complex binding

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Gene Ontology release 2020-05-02

Gene Ontology ID

GOA release 2020-03-11

cystic fibrosis transmembrane conductance regulator

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GOA release 2020-03-11

5

object named as

E J Sorscher

author given names

E J

author last names

Sorscher

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PubMed publication ID

6 February 2023

author name string

Z Bebök

1

author given names

Z

author last names

Bebök

1 reference

PubMed publication ID

6 February 2023

C Mazzochi

2

author given names

C

author last names

Mazzochi

1 reference

PubMed publication ID

6 February 2023

S A King

3

author given names

S A

author last names

King

1 reference

PubMed publication ID

6 February 2023

J S Hong

4

author given names

J S

author last names

Hong

1 reference

PubMed publication ID

6 February 2023

language of work or name

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publication date

6 November 1998

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Journal of Biological Chemistry

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273

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45

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29873-8

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Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

7 January 2021

based on heuristic

inferred from DOI database lookup

The Sec61 complex is essential for the insertion of proteins into the membrane of the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

7 January 2021

based on heuristic

inferred from DOI database lookup

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

7 January 2021

based on heuristic

inferred from DOI database lookup

Degradation of CFTR by the ubiquitin-proteasome pathway

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple proteolytic systems, including the proteasome, contribute to CFTR processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mechanism of membrane protein integration into the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

7 January 2021

based on heuristic

inferred from DOI database lookup

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

7 January 2021

based on heuristic

inferred from DOI database lookup

Approaching the mechanism of protein transport across the ER membrane.

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

7 January 2021

based on heuristic

inferred from DOI database lookup

A proteolytic system that compensates for loss of proteasome function

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https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

7 January 2021

based on heuristic

inferred from DOI database lookup

Product review. New mammalian expression vectors

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

7 January 2021

based on heuristic

inferred from DOI database lookup

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

7 January 2021

based on heuristic

inferred from DOI database lookup

Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations

1 reference

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7 January 2021

based on heuristic

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Demonstration of a peptide:N-glycosidase in the endoplasmic reticulum of rat liver

1 reference

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Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase

1 reference

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Aberrant retention of tyrosinase in the endoplasmic reticulum mediates accelerated degradation of the enzyme and contributes to the dedifferentiated phenotype of amelanotic melanoma cells

1 reference

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7 January 2021

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Site-specific de-N-glycosylation of diglycosylated ovalbumin in hen oviduct by endogenous peptide: N-glycanase as a quality control system for newly synthesized proteins

1 reference

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Similar processes mediate glycopeptide export from the endoplasmic reticulum in mammalian cells and Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

7 January 2021

based on heuristic

inferred from DOI database lookup

Discrete cross-linking products identified during membrane protein biosynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

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based on heuristic

inferred from DOI database lookup

Cytosolic Degradation of T-cell Receptor α Chains by the Proteasome

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Cotranslational ubiquitination of cystic fibrosis transmembrane conductance regulator in vitro

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Ubiquitination is required for the retro-translocation of a short-lived luminal endoplasmic reticulum glycoprotein to the cytosol for degradation by the proteasome

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Complex, two-way traffic of molecules across the membrane of the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

7 January 2021

based on heuristic

inferred from DOI database lookup

Calnexin and other factors that alter translocation affect the rapid binding of ubiquitin to apoB in the Sec61 complex

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Multiubiquitin chain binding and protein degradation are mediated by distinct domains within the 26 S proteasome subunit Mcb1.

1 reference

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7 January 2021

based on heuristic

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Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components

1 reference

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based on heuristic

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Novel aspects of degradation of T cell receptor subunits from the endoplasmic reticulum (ER) in T cells: importance of oligosaccharide processing, ubiquitination, and proteasome-dependent removal from ER membranes

1 reference

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based on heuristic

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Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular architecture of the ER translocase probed by chemical crosslinking of Sss1p to complementary fragments of Sec61p

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.45.29873

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based on heuristic

inferred from DOI database lookup

Biochemistry, molecular biology, and genetics of the oligosaccharyltransferase.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Use of a hybrid vaccinia virus-T7 RNA polymerase system for expression of target genes

1 reference

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inferred from DOI database lookup

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10.1074/JBC.273.45.29873

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