Peptidoglycan recognition protein 2 (Q21980088)

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mammalian protein found in Mus musculus

• PGRP-L
• N-acetylmuramoyl-L-alanine amidase
• Pglyrp2
• peptidoglycan recognition protein long
• TagL

edit

Language	Label	Description	Also known as
English	Peptidoglycan recognition protein 2	mammalian protein found in Mus musculus	PGRP-L N-acetylmuramoyl-L-alanine amidase Pglyrp2 peptidoglycan recognition protein long TagL

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

12 September 2018

UniProt protein ID

Q8VCS0

part of

N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8VCS0

Peptidoglycan recognition protein

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8VCS0

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Peptidoglycan recognition protein family domain, metazoa/bacteria, protein family

1 reference

based on heuristic

inferred from protein domain or family

N-acetylmuramoyl-L-alanine amidase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

house mouse

1 reference

stated in

UniProt

retrieved

12 September 2018

UniProt protein ID

Q8VCS0

encoded by

Pglyrp2

1 reference

stated in

UniProt

retrieved

12 September 2018

UniProt protein ID

Q8VCS0

molecular function

zinc ion binding

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

hydrolase activity

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

peptidoglycan immune receptor activity

determination method or standard

ISS

IEA

ISO

3 references

retrieved

31 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISS

retrieved

31 January 2018

stated in

Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISO

retrieved

31 January 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

peptidoglycan binding

determination method or standard

ISS

IEA

ISO

3 references

retrieved

31 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISS

retrieved

31 January 2018

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISO

retrieved

31 January 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

metal ion binding

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

N-acetylmuramoyl-L-alanine amidase activity

determination method or standard

IEA

ISO

3 references

retrieved

31 January 2018

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISO

retrieved

31 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

retrieved

31 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

N-acetylmuramoyl-L-alanine amidase activity

determination method or standard

IBA

IEA

ISO

4 references

retrieved

10 September 2018

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISO

retrieved

10 September 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

retrieved

10 September 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

retrieved

10 September 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

IBA

peptidoglycan immune receptor activity

determination method or standard

IBA

IEA

ISO

ISS

4 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISS

retrieved

14 February 2019

stated in

Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISO

retrieved

14 February 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

retrieved

14 February 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IBA

peptidoglycan binding

determination method or standard

IBA

IEA

ISO

ISS

4 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISS

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISO

retrieved

14 February 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

retrieved

14 February 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IBA

N-acetylmuramoyl-L-alanine amidase activity

determination method or standard

IBA

IEA

3 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

retrieved

14 February 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IBA

cell component

extracellular region

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

membrane

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

extracellular space

determination method or standard

IBA

1 reference

retrieved

14 February 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IBA

biological process

defense response to Gram-positive bacterium

determination method or standard

ISS

IEA

ISO

3 references

retrieved

31 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISS

retrieved

31 January 2018

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISO

retrieved

31 January 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

negative regulation of natural killer cell differentiation involved in immune response

determination method or standard

IMP

1 reference

retrieved

31 January 2018

stated in

Peptidoglycan recognition proteins protect mice from experimental colitis by promoting normal gut flora and preventing induction of interferon-gamma

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8VCS0&geneProductId=UniProtKB:Q8VCS0

determination method or standard

IMP

negative regulation of interferon-gamma production

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Peptidoglycan recognition proteins protect mice from experimental colitis by promoting normal gut flora and preventing induction of interferon-gamma

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IMP

detection of bacterium

determination method or standard

ISS

IEA

ISO

3 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISS

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISO

retrieved

14 February 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

regulation of inflammatory response

determination method or standard

IMP

2 references

retrieved

14 February 2019

stated in

PGLYRP-2 and Nod2 are both required for peptidoglycan-induced arthritis and local inflammation

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IMP

retrieved

14 February 2019

stated in

Peptidoglycan recognition protein Pglyrp2 protects mice from psoriasis-like skin inflammation by promoting regulatory T cells and limiting Th17 responses

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IMP

immune system process

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

peptidoglycan catabolic process

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

pattern recognition receptor signaling pathway

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

antimicrobial humoral response

determination method or standard

IBA

1 reference

retrieved

14 February 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IBA

negative regulation of natural killer cell differentiation involved in immune response

determination method or standard

IBA

IMP

2 references

retrieved

14 February 2019

stated in

Peptidoglycan recognition proteins protect mice from experimental colitis by promoting normal gut flora and preventing induction of interferon-gamma

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IMP

retrieved

14 February 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IBA

defense response to Gram-positive bacterium

determination method or standard

IBA

IEA

ISO

ISS

4 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8VCS0

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISS

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

ISO

retrieved

14 February 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IEA

retrieved

14 February 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VCS0

determination method or standard

IBA

has part(s)

Peptidoglycan recognition protein family domain, metazoa/bacteria

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8VCS0

N-acetylmuramoyl-L-alanine amidase domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8VCS0

Identifiers

RefSeq protein ID

NP_001258405

1 reference

stated in

NCBI Gene

retrieved

18 March 2019

Entrez Gene ID

57757

NP_001258406

1 reference

stated in

NCBI Gene

retrieved

18 March 2019

Entrez Gene ID

57757

NP_001258407

1 reference

stated in

NCBI Gene

retrieved

18 March 2019

Entrez Gene ID

57757

NP_001258408

1 reference

stated in

NCBI Gene

retrieved

18 March 2019

Entrez Gene ID

57757

NP_067294

1 reference

stated in

NCBI Gene

retrieved

18 March 2019

Entrez Gene ID

57757

XP_006524773

1 reference

stated in

NCBI Gene

retrieved

18 March 2019

Entrez Gene ID

57757

XP_006524774

1 reference

stated in

NCBI Gene

retrieved

18 March 2019

Entrez Gene ID

57757

XP_006524775

1 reference

stated in

NCBI Gene

retrieved

18 March 2019

Entrez Gene ID

57757

XP_006524776

1 reference

stated in

NCBI Gene

retrieved

18 March 2019

Entrez Gene ID

57757

XP_006524777

1 reference

stated in

NCBI Gene

retrieved

18 March 2019

Entrez Gene ID

57757

UniProt protein ID

Q8VCS0

1 reference

stated in

UniProt

retrieved

12 September 2018

UniProt protein ID

Q8VCS0

Ensembl protein ID

ENSMUSP00000110099

1 reference

stated in

ensembl Release 95

Ensembl protein ID

ENSMUSP00000110099

ENSMUSP00000129964

1 reference

stated in

ensembl Release 95

Ensembl protein ID

ENSMUSP00000129964

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

edit

Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q21980088&oldid=2023193525"