POU domain, class 3, transcription factor 1 (Q21986671)

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mammalian protein found in Mus musculus

• Oct-6
• OTF-6
• octamer-binding protein 6
• octamer-binding transcription factor 6
• octamer binding factor oct6
• POU domain transcription factor SCIP
• Pou3f1

edit

Language	Label	Description	Also known as
English	POU domain, class 3, transcription factor 1	mammalian protein found in Mus musculus	Oct-6 OTF-6 octamer-binding protein 6 octamer-binding transcription factor 6 octamer binding factor oct6 POU domain transcription factor SCIP Pou3f1

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P21952

subclass of

protein

1 reference

stated in

UniProt

retrieved

19 January 2017

UniProt protein ID

P21952

part of

Lambda repressor-like, DNA-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P21952

POU-domain transcription factor, class 3

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P21952

Homeobox-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P21952

Homeobox domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

POU domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

POU-specific domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Homeobox, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

house mouse

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P21952

encoded by

Pou3f1

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P21952

molecular function

DNA-binding transcription factor activity

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IEA

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

determination method or standard

ISO

1 reference

retrieved

5 June 2018

stated in

Cooperative function of POU proteins and SOX proteins in glial cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21952&geneProductId=UniProtKB:P21952

determination method or standard

ISO

DNA binding

determination method or standard

IDA

IEA

3 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P21952

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IEA

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IEA

retrieved

14 February 2019

stated in

The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IDA

transcription coactivator activity

determination method or standard

IDA

2 references

retrieved

1 January 2018

stated in

Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors

GOA

curator

UniProt

UniProt protein ID

P21952

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21952&geneProductId=UniProtKB:P21952

determination method or standard

IDA

retrieved

14 February 2019

stated in

Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors

GOA

curator

UniProt

UniProt protein ID

P21952

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IDA

sequence-specific DNA binding

determination method or standard

IEA

ISO

3 references

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

ISO

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IEA

retrieved

14 February 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IEA

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

ISO

1 reference

retrieved

14 February 2019

stated in

Cooperative function of POU proteins and SOX proteins in glial cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

ISO

cell component

nucleus

determination method or standard

IDA

IEA

4 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P21952

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IEA

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IEA

retrieved

14 February 2019

stated in

The class III POU domain protein Brn-1 can fully replace the related Oct-6 during schwann cell development and myelination

GOA

curator

UniProt

UniProt protein ID

P21952

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IDA

retrieved

14 February 2019

stated in

Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IDA

transcription regulator complex

determination method or standard

IDA

1 reference

retrieved

14 February 2019

stated in

The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IDA

nucleoplasm

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IEA

biological process

regulation of transcription by RNA polymerase II

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IEA

positive regulation of transcription, DNA-templated

determination method or standard

IDA

1 reference

retrieved

14 February 2019

stated in

The class III POU domain protein Brn-1 can fully replace the related Oct-6 during schwann cell development and myelination

GOA

curator

UniProt

UniProt protein ID

P21952

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IDA

Schwann cell development

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IMP

forebrain development

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Replacement of related POU transcription factors leads to severe defects in mouse forebrain development

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IMP

myelination

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Cell autonomy of the mouse claw paw mutation

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IMP

brain development

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IEA

positive regulation of gene expression

determination method or standard

IDA

1 reference

retrieved

14 February 2019

stated in

The class III POU domain protein Brn-1 can fully replace the related Oct-6 during schwann cell development and myelination

GOA

curator

UniProt

UniProt protein ID

P21952

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IDA

regulation of transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IEA

transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

5 June 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P21952

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21952&geneProductId=UniProtKB:P21952

determination method or standard

IEA

myelination in peripheral nervous system

determination method or standard

IGI

1 reference

retrieved

14 February 2019

stated in

The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IGI

keratinocyte differentiation

determination method or standard

IGI

1 reference

retrieved

14 February 2019

stated in

Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IGI

epidermis development

determination method or standard

IGI

1 reference

retrieved

14 February 2019

stated in

Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

IGI

positive regulation of transcription by RNA polymerase II

determination method or standard

ISO

1 reference

retrieved

14 February 2019

stated in

Cooperative function of POU proteins and SOX proteins in glial cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21952

determination method or standard

ISO

transcription by RNA polymerase II

determination method or standard

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21952&geneProductId=UniProtKB:P21952

determination method or standard

IEA

has part(s)

Homeobox, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P21952

POU domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P21952

POU-specific domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P21952

Homeobox domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P21952

Identifiers

RefSeq protein ID

NP_035271

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

18991

UniProt protein ID

P21952

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

P21952

Ensembl protein ID

ENSMUSP00000137374

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000137374

PDB structure ID

2XSD

1 reference

stated in

UniProt

UniProt protein ID

P21952

retrieved

21 March 2016

language of work or name

English

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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