Mitogen-activated protein kinase kinase kinase kinase 2 (Q21985111)

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mammalian protein found in Mus musculus

MEK kinase kinase 2
germinal center kinase
MAPK/ERK kinase kinase kinase 2
Map4k2
GCK
rab8-interacting protein
MEKKK 2
RAB8 interacting protein
mitogen-activated protein kinase kinase kinase kinase 2

Language	Label	Description	Also known as
English	Mitogen-activated protein kinase kinase kinase kinase 2	mammalian protein found in Mus musculus	MEK kinase kinase 2 germinal center kinase MAPK/ERK kinase kinase kinase 2 Map4k2 GCK rab8-interacting protein MEKKK 2 RAB8 interacting protein mitogen-activated protein kinase kinase kinase kinase 2

Statements

1 reference

25 May 2022

UniProt protein ID

mitogen-activated protein (MAP) kinase kinase kinase kinase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61161

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61161

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Citron homology (CNH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

transferase activity

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

nucleotide binding

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

protein kinase activity

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

kinase activity

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

determination method or standard

5 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

protein serine/threonine kinase activity

determination method or standard

3 references

protein serine/threonine kinase activity

determination method or standard

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

Golgi apparatus

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

plasma membrane

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

basolateral plasma membrane

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

biological process

intracellular signal transduction

determination method or standard

vesicle targeting

determination method or standard

1 reference

14 February 2019

In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

phosphorylation

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

immune system process

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

protein phosphorylation

determination method or standard

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

innate immune response

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

regulation of mitotic cell cycle

determination method or standard

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61161&geneProductId=UniProtKB:Q61161

determination method or standard

stress-activated protein kinase signaling cascade

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

regulation of apoptotic process

determination method or standard

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61161&geneProductId=UniProtKB:Q61161

determination method or standard

signal transduction

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

activation of protein kinase activity

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161

determination method or standard

Citron homology (CNH) domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61161

protein kinase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61161

protein kinase, ATP binding site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61161

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000025897

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000025897

ENSMUSP00000121375

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000121375

ENSMUSP00000121856

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000121856

ENSMUSP00000114243

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000114243

ENSMUSP00000115741

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000115741

ENSMUSP00000120123

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000120123

ENSMUSP00000158086

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000158086

ENSMUSP00000158007

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000158007

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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